1. 2015
  2. Published

    Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons

    Boza-Morán, M. G., Martínez-Hernández, R., Bernal, S., Wanisch, K., Also-Rallo, E., le Heron, A., Alías, L., Denis, C., Girard, M., Yee, J-K., Tizzano, E. F. & Yanez, R. 26 Jun 2015 In : Scientific reports. 5, 17 p., 11696

    Research output: Contribution to journalArticle

  3. Published

    Progress on gene therapy, cell therapy and pharmacological strategies towards the treatment of Oculopharyngeal Muscular Dystrophy

    Harish, P., Malerba, A., Dickson, G. & Bachtarzi, H. 19 May 2015 In : Human Gene Therapy. 26, 5, p. 286-292 7 p.

    Research output: Contribution to journalArticle

  4. Published
  5. Published

    Enhanced efficacy of the CDNF/MANF family by combined intranigral overexpression in the 6-OHDA rat model of Parkinson's disease

    Cordero-Llana, Ó., Houghton, B. C., Rinaldi, F., Taylor, H., Yáñez-Muñoz, R. J., Uney, J. B., Wong, L-F. & Caldwell, M. A. Feb 2015 In : Molecular Therapy. 23, 2, p. 244-54 11 p.

    Research output: Contribution to journalArticle

  6. Published

    Annotation and functional assignment of the genes for the C-30 carotenoid pathways from the genomes of two bacteria: Bacillus indicus and Bacillus firmus

    Steiger, S., Perez-Fons, L., Cutting, S. M., Fraser, P. D. & Sandmann, G. 1 Jan 2015 In : Microbiology (Reading, England). 161, 1, p. 194-202 9 p.

    Research output: Contribution to journalArticle

  7. Published

    Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy

    Athanasopoulos, T. , Dickson, G. & 19 others Rau, F., Lainé, J., Ramanoudjame, L., Ferry, A., Arandel, L., Delalande, O., Jollet, A., Dingli, F., Lee, K-Y., Peccate, C., Lorain, S., Kabashi, E., Koo, T., Loew, D., Swanson, M. S., Le Rumeur, E., Allamand, V., Marie, J. & Furling, D. 2015 In : Nature Communications. 6, 7205

    Research output: Contribution to journalArticle

  8. Published

    Adeno-Associated Virus (AAV) Mediated Dystrophin Gene Transfer Studies and Exon Skipping Strategies for Duchenne Muscular Dystrophy (DMD)

    Kawecka, K., Theodoulides, M., Hasoglu, Y., Jarmin, S., Kymalainen, H., Le-Heron, A., Popplewell, L., Malerba, A., Dickson, G. & Athanasopoulos, T. 2015 In : Current Gene Therapy. 15, 4, p. 395-415 21 p.

    Research output: Contribution to journalArticle

  9. Published
  10. Published

    Mitochondrial dysfunction reveals the role of mRNA poly(a) tail regulation in oculopharyngeal muscular dystrophy pathogenesis

    Chartier, A., Klein, P., Pierson, S., Barbezier, N., Gidaro, T., Casas, F., Carberry, S., Dowling, P., Maynadier, L., Bellec, M., Oloko, M., Jardel, C., Moritz, B., Dickson, G., Mouly, V., Ohlendieck, K., Butler-Browne, G., Trollet, C. & Simonelig, M. 2015 In : PLoS genetics. 11, 3, p. e1005092

    Research output: Contribution to journalArticle

  11. Published

    New experimental therapies for status epilepticus in pre-clinical development

    Walker, M. & Williams, R. 2015 In : Epilepsy and Behaviour.

    Research output: Contribution to journalScientific review

  12. Forthcoming

    Valproic acid protects against haemorrhagic shock-induced signalling changes via PPARγ activation in an in vitro model

    Zuckermann, A., LaRagione, R., Baines, D. & Williams, R. 2015 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  13. 2014
  14. Published

    Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors

    Patel, H., Chuckowree, I., Coxhead, P., Guille, M., Wang, M., Zuckermann, A., Williams, R., Librizzi, M., Paranal, R. M., Bradner, J. E. & Spencer, J. 1 Dec 2014 In : MedChemComm. 12, p. 1829-1833 5 p.

    Research output: Contribution to journalArticle

  15. Published

    Primary Chemical Sequence Ultimately Determines Crystal Thickness in Segmented All-Aliphatic Copolymers

    Odarchenko, Y. I., Anokhin, D. V., Doblas, D., Rosenthal, M., Hernandez, J. J., Vidal, L., Sijbrandi, N. J., Kimenai, A. J., Mes, E. P. C., Broos, R., Bar, G., Dijkstra, P. J., Feijen, J., Soloviev, M. & Ivanov, D. A. 25 Nov 2014 In : Macromolecules. 47, 22, p. 7890-7899 10 p.

    Research output: Contribution to journalArticle

  16. Published

    Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

    Murdoch, J. N., Damrau, C., Paudyal, A., Bogani, D., Wells, S., Greene, N. D. E., Stanier, P. & Copp, A. J. Oct 2014 In : Disease Models and Mechanisms. 7, 10, p. 1153-63 11 p.

    Research output: Contribution to journalArticle

  17. Published

    Genome-Wide Computational Analysis Reveals Cardiomyocyte-Specific Transcriptional CIS-Regulatory Motifs that Enable Efficient Cardiac Gene Therapy

    Rincon, M. Y., Sarcar, S., Danso-Abeam, D., Keyaerts, M., Matrai, J., Samara-Kuko, E., Acosta-Sanchez, A., Athanasopoulos, T., Dickson, G., Lahoutte, T., De Bleser, P., VandenDriessche, T. & Chuah, M. K. 8 Sep 2014 In : Molecular Therapy.

    Research output: Contribution to journalArticle

  18. Published

    Local Overexpression of the Myostatin Propeptide Increases Glucose Transporter Expression and Enhances Skeletal Muscle Glucose Disposal

    Cleasby, M. E., Jarmin, S., Eilers, W., Elashry, M., Andersen, D. K., Dickson, G. & Foster, K. 1 Apr 2014 In : American Journal of Physiology. Endocrinology and Metabolism.

    Research output: Contribution to journalArticle

  19. Published

    Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

    Lu-Nguyen, N. B., Broadstock, M., Schliesser, M. G., Bartholomae, C., von Kalle, C., Schmidt, M. & Yáñez-Muñoz, R. J. 18 Mar 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  20. Published

    Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors (IDLVs)

    Kymalainen, H., Appelt, J-U., Giordano, F. A., Davies, A. F., Ogilvie, C. M., Ahmed, S. G., Laufs, S., Schmidt, M., Bode, J., Yáñez-Muñoz, R. J. & Dickson, G. 2 Feb 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  21. Published

    New developments in the use of gene therapy to treat Duchenne muscular dystrophy

    Jarmin, S., Kymalainen, H., Popplewell, L. & Dickson, G. Feb 2014 In : Expert Opinion on Biological Therapy. 14, 2, p. 209-30 22 p.

    Research output: Contribution to journalArticle

  22. Published

    Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid

    Chang, P., Walker, M. C. & Williams, R. Feb 2014 In : Neurobiology of Disease. 62, p. 296–306 10 p.

    Research output: Contribution to journalArticle

  23. Published
  24. Published

    A southern blot protocol to detect chimeric nuclease-mediated gene repair

    Rocca, C. J., Abdul-Razak, H. H., Holmes, M. C., Gregory, P. D. & Yáñez-Muñoz, R. J. 2014 In : Methods in Molecular Biology. 1114, p. 325-38 14 p.

    Research output: Contribution to journalArticle

  25. Published
  26. Published
  27. Published

    Fusion of Ubiquitin to HIV Gag Impairs Human Monocyte-Derived Dendritic Cell Maturation and Reduces Ability to Induce Gag T Cell Responses

    Herath, S., Benlahrech, A., Papagatsias, T., Athanasopoulos, T., Bouzeboudjen, Z., Hervouet, C., Klavinskis, L., Meiser, A., Kelleher, P., Dickson, G. & Patterson, S. 2014 In : PLoS One. 9, 2, p. e88327

    Research output: Contribution to journalArticle

  28. Published

    Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

    Bartus, K., James, N. D., Didangelos, A., Bosch, K. D., Verhaagen, J., Yáñez (or Yáñez-Muñoz), R. J., Rogers, J. H., Schneider, B. L., Muir, E. M. & Bradbury, E. J. 2014 In : The Journal of Neuroscience. 34, 14, p. 4822– 4836

    Research output: Contribution to journalArticle

  29. 2013
  30. Published

    Lentiviral Vector-Mediated RNA Silencing in the Central Nervous System

    Hutson, T. H., Foster, E., Moon, L. D. F. & Yáñez-Muñoz, R. J. 1 Nov 2013 In : Human Gene Therapy. Methods.

    Research output: Contribution to journalArticle

  31. Published

    Transgene delivery to endothelial cultures derived from porcine carotid artery ex vivo

    Andoh, J., Sawyer, B., Szewczyk, K., Nortley, M., Rossetti, T., Loftus, I. M., Yáñez-Muñoz, R. J. & Hainsworth, A. H. Oct 2013 In : Translational Stroke Research. 4, 5, p. 507-14 8 p.

    Research output: Contribution to journalArticle

  32. Published

    Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in

    Popplewell, L., Koo, T., Leclerc, X., Duclert, A., Mamchaoui, K., Gouble, A., Mouly, V., Voit, T., Pâques, F., Cédrone, F., Isman, O., Yáñez (or Yáñez-Muñoz), R. J. & Dickson, G. Jul 2013 In : Human Gene Therapy. 24, 7, p. 692-701 10 p.

    Research output: Contribution to journalArticle

  33. Published

    Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

    Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., Yip, P., Wanisch, K., Caraballo-Miralles, V., Olmos, G., Lladó, J., McMahon, S. B. & Yáñez-Muñoz, R. J. Jun 2013 In : Gene Therapy. 20, p. 645-657

    Research output: Contribution to journalArticle

  34. Published

    Functional characterization of Clostridium difficile spore coat proteins

    Permpoonpattana, P., Phetcharaburanin, J., Mikelsone, A., Dembek, M., Tan, S., Brisson, M-C., La Ragione, R., Brisson, A. R., Fairweather, N., Hong, H. A. & Cutting, S. M. 1 Apr 2013 In : Journal of Bacteriology. 195, 7, p. 1492-1503 12 p.

    Research output: Contribution to journalArticle

  35. Published

    Elevated Transcription of the Gene QSOX1 Encoding Quiescin Q6 Sulfhydryl Oxidase 1 in Breast Cancer

    Soloviev, M., Esteves, M. P., Amiri, F., Crompton, M. R. & Rider, C. 27 Feb 2013 In : PLoS One. 8, 2, e57327

    Research output: Contribution to journalArticle

  36. Published
  37. Published

    Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases

    Dickson, J. G. & 50 others Tremblay, J. P., Xiao, X., Aartsma-Rus, A., Barbas, C., Blau, H. M., Bogdanove, A. J., Boycott, K., Braun, S., Breakefield, X. O., Bueren, J. A., Buschmann, M., Byrne, B. J., Calos, M., Cathomen, T., Chamberlain, J., Chuah, M., Cornetta, K., Davies, K. E., Duchateau, P., Flotte, T. R., Gaudet, D., Gersbach, C. A., Gilbert, R., Glorioso, J., Herzog, R. W., High, K. A., Huang, W., Huard, J., Joung, J. K., Liu, D., Liu, D., Lochmüller, H., Lustig, L., Martens, J., Massie, B., Mavilio, F., Mendell, J. R., Nathwani, A., Ponder, K., Porteus, M., Puymirat, J., Samulski, J., Takeda, S., Thrasher, A., VandenDriessche, T., Wei, Y., Wilson, J. M., Wilton, S. D., Wolfe, J. H. & Gao, G. Feb 2013 In : Molecular Therapy. 21, 2, p. 266-8 3 p.

    Research output: Contribution to journalArticle

  38. Published

    Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung

    Yates, L. L., Schnatwinkel, C., Hazelwood, L., Chessum, L., Paudyal, A., Hilton, H., Romero, M. R., Wilde, J., Bogani, D., Sanderson, J., Formstone, C., Murdoch, J. N., Niswander, L. A., Greenfield, A. & Dean, C. H. 15 Jan 2013 In : Developmental Biology. 373, 2, p. 267-280 14 p.

    Research output: Contribution to journalArticle

  39. Published

    A novel human receptor involved in bitter tastant detection identified using the model organism Dictyostelium discoideum

    Robery, S., Tyson, R., Dinh, C., Kuspa, A., Noegel, A., Bretschneider, T., Andrews, P. L. R. & Williams, R. S. B. 2013 In : Journal of Cell Science.

    Research output: Contribution to journalArticle

  40. Published

    Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

    Bachy, V., Hervouet, C., Becker, P. D., Chorro, L., Carlin, L. M., Herath, S., Papagatsias, T., Barbaroux, J-B., Oh, S-J., Benlahrech, A., Athanasopoulos, T., Dickson, G., Patterson, S., Kwon, S-Y., Geissmann, F. & Klavinskis, L. S. 2013 In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

  41. Published

    Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

    Novorol, C., Burkhardt, J., Wood, K. J., Iqbal, A., Roque, C., Coutts, N., Almeida, A. D., He, J., Wilkinson, C. J. & Harris, W. A. 2013 In : Open biology. 3, 10, p. 130065

    Research output: Contribution to journalArticle

  42. Published

    Mucosal Vaccination against Tuberculosis Using Inert Bioparticles

    Reljic, R., Sibley, L., Huang, J-M., Pepponi, I., Hoppe, A., Huynh, H. & Cutting, S. M. 2013 In : Infection and Immunity. 81, 11, p. 4071-4080

    Research output: Contribution to journalArticle

  43. Forthcoming

    Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner

    Waheed, A., Ludtmann, M., Pakes, N., Robery, S., Kuspa, A., Dinh, C., Baines, D. L., Williams, R. & Carew, M. 2013 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  44. Published

    Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy

    Raz, V., Sterrenburg, E., Routledge, S., Venema, A., van der Sluijs, B. M., Trollet, C., Dickson, G., van Engelen, B. G. M., van der Maarel, S. M. & Antoniou, M. N. 2013 In : BMC Neurology. 13, p. 70

    Research output: Contribution to journalArticle

  45. Forthcoming

    The search for better epilepsy treatments: from slime mould to coconuts

    Williams, R. & Walker, M. C. 2013 In : Biochemical Society Transactions. 41

    Research output: Contribution to journalScientific review

  46. Published

    Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

    Pakes, N., Veltman, D. M. & Williams, R. 2013 In : Small GTPases. 4, 1, p. 1-6 6 p.

    Research output: Contribution to journalScientific review

  47. 2012
  48. Published

    Fragmentation of SIV-gag Vaccine Induces Broader T Cell Responses

    Benlahrech, A., Meiser, A., Herath, S., Papagatsias, T., Athanasopoulos, T., Li, F., Self, S., Bachy, V., Hervouet, C., Logan, K., Klavinskis, L., Dickson, G. & Patterson, S. 31 Oct 2012 In : PLoS One. 7, 10, 13 p., ARTN e48038

    Research output: Contribution to journalArticle

  49. Published

    Seizure control by ketogenic diet-associated medium chain fatty acids

    Chang, P., Terbach, N., Plant, N., Chen, P. E., Walker, M. C. & Williams, R. S. B. Jun 2012 In : Neuropharmacology. 69, p. 105-114

    Research output: Contribution to journalArticle

  50. Published

    The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium

    Pakes, N. K., Veltman, D. M., Rivero, F., Nasir, J., Insall, R. & Williams, R. S. B. 15 May 2012 In : Journal of Cell Science. 125, Pt 10, p. 2457-65 9 p.

    Research output: Contribution to journalArticle

  51. Published

    Highly potent delivery method of gp160 envelope vaccine combining lentivirus-like particles and DNA electrotransfer

    Vandermeulen, G., Athanasopoulos, T., Trundley, A., Foster, K., Préat, V., Yáñez-Muñoz, R. J. & Dickson, G. 10 May 2012 In : Journal of Controlled Release. 159, 3, p. 376–383

    Research output: Contribution to journalArticle

  52. Published

    Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds

    Elphick, L. M., Pawolleck, N., Guschina, I. A., Chaieb, L., Eikel, D., Nau, H., Harwood, J. L., Plant, N. J. & Williams, R. S. B. Mar 2012 In : Disease Models and Mechanisms. 5, 2, p. 231-240 10 p.

    Research output: Contribution to journalArticle

  53. Published

    Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

    Hutson, T. H., Verhaagen, J., Yáñez-Muñoz, R. J. & Moon, L. D. F. Jan 2012 In : Gene Therapy. 19, 1, p. 49-60 12 p.

    Research output: Contribution to journalArticle

  54. Published

    AMP-Activated Protein Kinase (AMPK) - Dependent and -Independent Pathways Regulate Hypoxic Inhibition of Transepithelial Na(+) Transport Across Human Airway Epithelial Cells

    Tan, C. D., Smolenski, R. T., Harhun, M. I., Patel, H. K., Ahmed, S. G., Wanisch, K., Yáñez (or Yáñez-Muñoz) , R. J. & Baines, D. L. 2012 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

Previous 1 2 3 4 5 6 7 8 ...12 Next