Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

Andrew D White; Andy C. Tran; Laura Sibley; Charlotte Sarfas; Alexandra L Morrison; Steve Lawrence; Mike Dennis; Simon Clark; Sirine Zadi; Faye Lanni; Emma Rayner; Alastair Copland; Peter  Hart; Gil R Diogo; Mathew Paul; Miyoung Kim; Fergus Gleeson; Francisco Javier Salguero; Mahavir Singh; Matthias Stehr; Simon Cutting; Juan I Basile; Martin Rottenberg; Ann Williams; Sally A Sharpe; Rajko Reljic

doi:10.3389/fimmu.2023.1246826

Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

Andrew D White, Andy C. Tran, Laura Sibley, Charlotte Sarfas, Alexandra L Morrison, Steve Lawrence, Mike Dennis, Simon Clark, Sirine Zadi, Faye Lanni, Emma Rayner, Alastair Copland, Peter Hart, Gil R Diogo, Mathew Paul, Miyoung Kim, Fergus Gleeson, Francisco Javier Salguero, Mahavir Singh, Matthias StehrSimon Cutting, Juan I Basile, Martin Rottenberg, Ann Williams, Sally A Sharpe, Rajko Reljic

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Original language	English
Journal	Frontiers in Immunology
Volume	14
DOIs	https://doi.org/10.3389/fimmu.2023.1246826
Publication status	Published - 10 Oct 2023

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10.3389/fimmu.2023.1246826Licence: CC BY

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White, A. D., Tran, A. C., Sibley, L., Sarfas, C., Morrison, A. L., Lawrence, S., Dennis, M., Clark, S., Zadi, S., Lanni, F., Rayner, E., Copland, A., Hart, P., Diogo, G. R., Paul, M., Kim, M., Gleeson, F., Salguero, F. J., Singh, M., ... Reljic, R. (2023). Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1246826

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title = "Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates",

author = "White, {Andrew D} and Tran, {Andy C.} and Laura Sibley and Charlotte Sarfas and Morrison, {Alexandra L} and Steve Lawrence and Mike Dennis and Simon Clark and Sirine Zadi and Faye Lanni and Emma Rayner and Alastair Copland and Peter Hart and Diogo, {Gil R} and Mathew Paul and Miyoung Kim and Fergus Gleeson and Salguero, {Francisco Javier} and Mahavir Singh and Matthias Stehr and Simon Cutting and Basile, {Juan I} and Martin Rottenberg and Ann Williams and Sharpe, {Sally A} and Rajko Reljic",

year = "2023",

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doi = "10.3389/fimmu.2023.1246826",

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White, AD, Tran, AC, Sibley, L, Sarfas, C, Morrison, AL, Lawrence, S, Dennis, M, Clark, S, Zadi, S, Lanni, F, Rayner, E, Copland, A, Hart, P, Diogo, GR, Paul, M, Kim, M, Gleeson, F, Salguero, FJ, Singh, M, Stehr, M, Cutting, S, Basile, JI, Rottenberg, M, Williams, A, Sharpe, SA & Reljic, R 2023, 'Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates', Frontiers in Immunology, vol. 14. https://doi.org/10.3389/fimmu.2023.1246826

TY - JOUR

T1 - Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

AU - White, Andrew D

AU - Tran, Andy C.

AU - Sibley, Laura

AU - Sarfas, Charlotte

AU - Morrison, Alexandra L

AU - Lawrence, Steve

AU - Dennis, Mike

AU - Clark, Simon

AU - Zadi, Sirine

AU - Lanni, Faye

AU - Rayner, Emma

AU - Copland, Alastair

AU - Hart, Peter

AU - Diogo, Gil R

AU - Paul, Mathew

AU - Kim, Miyoung

AU - Gleeson, Fergus

AU - Salguero, Francisco Javier

AU - Singh, Mahavir

AU - Stehr, Matthias

AU - Cutting, Simon

AU - Basile, Juan I

AU - Rottenberg, Martin

AU - Williams, Ann

AU - Sharpe, Sally A

AU - Reljic, Rajko

PY - 2023/10/10

Y1 - 2023/10/10

U2 - 10.3389/fimmu.2023.1246826

DO - 10.3389/fimmu.2023.1246826

M3 - Article

SN - 1664-3224

VL - 14

JO - Frontiers in Immunology

JF - Frontiers in Immunology

ER -