Does including the full CVLT-II and BVMT-R improve BICAMS? Evidence from a Belgian (Dutch) validation study. / Costers, Lars; Gielen, Jeroen; Eelen, Piet L.; Van Shependom, Jeroen; Laton, Jorne; Van Remoortel, Ann; Vanzeir, Ellen; Van Wijmeersch, Bart; Seeldrayers, Pierrette; Haelewyck, Marie-Claire; D'Haeseleer, Miguel; D'hooghe, Marie-Beatrice; Langdon, Dawn; Nagels, Guy.

In: Multiple sclerosis and related disorders, Vol. 18, 11.2017, p. 33-40.

Research output: Contribution to journalArticlepeer-review



  • Lars Costers
  • Jeroen Gielen
  • Piet L. Eelen
  • Jeroen Van Shependom
  • Jorne Laton
  • Ann Van Remoortel
  • Ellen Vanzeir
  • Bart Van Wijmeersch
  • Pierrette Seeldrayers
  • Marie-Claire Haelewyck
  • Miguel D'Haeseleer
  • Marie-Beatrice D'hooghe
  • Dawn Langdon
  • Guy Nagels



The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) is a fast, easy-to-administer and already widely validated neuropsychological battery for cognition in multiple sclerosis.


The goals of our study were to validate the BICAMS in a Belgian Dutch-speaking population and to investigate to what extent including extensive versions of two of the three BICAMS subtests improved its psychometric qualities.


Ninety-seven persons with MS and ninety-seven healthy controls were included and group-matched on age, education level and gender. All participants performed the BICAMS with an extensive version of the CVLT-II and BVMT-R.


The SDMT and BVMT-R were able to dissociate between the MS and healthy control group, while the CVLT-II was not. Distributions of CVLT-II scores suggest learning effects in the MS group, indicating the need for alternative word lists or the construction of an adapted version fitted for repeated administration. Including the full CVLT-II and BVMT-R did not markedly improve the psychometric qualities of the BICAMS.


This study validates the BICAMS in a Belgian Dutch-speaking population and facilitates the use of it in clinical practice, while providing evidence that including full versions of the CVLT-II and BVMT-R does not increase its psychometric qualities markedly.
Original languageEnglish
Pages (from-to)33-40
Number of pages8
JournalMultiple sclerosis and related disorders
Early online date7 Sep 2017
Publication statusPublished - Nov 2017
This open access research output is licenced under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.

ID: 28640939