Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties

Celestine Lockhart; Joanna Bright; Yasmin Ahmadzadeh; Gerome Breen; Shannon Bristow; Andy Boyd; Johnny Downs; Matthew Hotopf; Elisavet Palaiologou; Kaili Rimfeld; Jessye Maxwell; Margherita Malanchini; Tom A McAdams; Andrew McMillan; Robert Plomin; Thalia C Eley

doi:10.1002/jcv2.12154

Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties

Celestine Lockhart, Joanna Bright, Yasmin Ahmadzadeh, Gerome Breen, Shannon Bristow, Andy Boyd, Johnny Downs, Matthew Hotopf, Elisavet Palaiologou, Kaili Rimfeld, Jessye Maxwell, Margherita Malanchini, Tom A McAdams, Andrew McMillan, Robert Plomin, Thalia C Eley

Health & Social Care

Research output: Contribution to journal › Article › peer-review

Abstract

The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.

Original language	English
Article number	e12154
Journal	JCPP Advances
Volume	3
Issue number	2
Early online date	30 Mar 2023
DOIs	https://doi.org/10.1002/jcv2.12154
Publication status	Published - Jun 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/jcv2.12154Licence: CC BY

Cite this

Lockhart, C., Bright, J., Ahmadzadeh, Y., Breen, G., Bristow, S., Boyd, A., Downs, J., Hotopf, M., Palaiologou, E., Rimfeld, K., Maxwell, J., Malanchini, M., McAdams, T. A., McMillan, A., Plomin, R., & Eley, T. C. (2023). Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties. JCPP Advances, 3(2), Article e12154. https://doi.org/10.1002/jcv2.12154

@article{5e5495f7a966437cace059bf0eccbd72,

title = "Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties",

abstract = "The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.",

author = "Celestine Lockhart and Joanna Bright and Yasmin Ahmadzadeh and Gerome Breen and Shannon Bristow and Andy Boyd and Johnny Downs and Matthew Hotopf and Elisavet Palaiologou and Kaili Rimfeld and Jessye Maxwell and Margherita Malanchini and McAdams, {Tom A} and Andrew McMillan and Robert Plomin and Eley, {Thalia C}",

note = "{\textcopyright} 2023 The Authors. JCPP Advances published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.",

year = "2023",

month = jun,

doi = "10.1002/jcv2.12154",

language = "English",

volume = "3",

journal = "JCPP Advances",

issn = "2692-9384",

publisher = "Wiley",

number = "2",

}

Lockhart, C, Bright, J, Ahmadzadeh, Y, Breen, G, Bristow, S, Boyd, A, Downs, J, Hotopf, M, Palaiologou, E, Rimfeld, K, Maxwell, J, Malanchini, M, McAdams, TA, McMillan, A, Plomin, R & Eley, TC 2023, 'Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties', JCPP Advances, vol. 3, no. 2, e12154. https://doi.org/10.1002/jcv2.12154

TY - JOUR

T1 - Twins Early Development Study (TEDS)

T2 - A genetically sensitive investigation of mental health outcomes in the mid-twenties

AU - Lockhart, Celestine

AU - Bright, Joanna

AU - Ahmadzadeh, Yasmin

AU - Breen, Gerome

AU - Bristow, Shannon

AU - Boyd, Andy

AU - Downs, Johnny

AU - Hotopf, Matthew

AU - Palaiologou, Elisavet

AU - Rimfeld, Kaili

AU - Maxwell, Jessye

AU - Malanchini, Margherita

AU - McAdams, Tom A

AU - McMillan, Andrew

AU - Plomin, Robert

AU - Eley, Thalia C

PY - 2023/6

Y1 - 2023/6

N2 - The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.

AB - The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.

U2 - 10.1002/jcv2.12154

DO - 10.1002/jcv2.12154

M3 - Article

C2 - 37753150

SN - 2692-9384

VL - 3

JO - JCPP Advances

JF - JCPP Advances

IS - 2

M1 - e12154

ER -