Long-term follow-up of the original interferon-beta1b trial in multiple sclerosis: design and lessons from a 16-year observational study

George C Ebers, Anthony T Reder, Anthony Traboulsee, David Li, Dawn Langdon, Douglas S Goodin, Christian Wolf, Karola Beckmann, Andreas Konieczny, Investigators of the 16-Year Long-Term Follow-Up Study

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1724-36
Number of pages13
JournalClinical Therapeutics
Issue number8
Publication statusPublished - Aug 2009


  • Adjuvants, Immunologic
  • Adult
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Female
  • Follow-Up Studies
  • Humans
  • Interferon-beta
  • Male
  • Multiple Sclerosis, Relapsing-Remitting
  • Patient Dropouts
  • Randomized Controlled Trials as Topic
  • Retrospective Studies
  • Validation Studies as Topic
  • Young Adult

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