Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice

Taeyoung Koo; Alberto Malerba; Takis Athanasopoulos; Capucine Trollet; Luisa Boldrin; Arnaud Ferry; Linda J Popplewell; Helen Foster; Keith Foster; George Dickson

doi:10.1089/hum.2011.020

Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice

Taeyoung Koo, Alberto Malerba, Takis Athanasopoulos, Capucine Trollet, Luisa Boldrin, Arnaud Ferry, Linda J Popplewell, Helen Foster, Keith Foster, George Dickson

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Human Gene Therapy
DOIs	https://doi.org/10.1089/hum.2011.020
Publication status	Published - 2011

Access to Document

10.1089/hum.2011.020

Cite this

Koo, T., Malerba, A., Athanasopoulos, T., Trollet, C., Boldrin, L., Ferry, A., Popplewell, L. J., Foster, H., Foster, K., & Dickson, G. (2011). Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice. Human Gene Therapy. https://doi.org/10.1089/hum.2011.020

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title = "Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice",

author = "Taeyoung Koo and Alberto Malerba and Takis Athanasopoulos and Capucine Trollet and Luisa Boldrin and Arnaud Ferry and Popplewell, {Linda J} and Helen Foster and Keith Foster and George Dickson",

year = "2011",

doi = "10.1089/hum.2011.020",

language = "English",

journal = "Human Gene Therapy",

issn = "1557-7422",

publisher = "Mary Ann Liebert Inc.",

}

Koo, T, Malerba, A, Athanasopoulos, T, Trollet, C, Boldrin, L, Ferry, A, Popplewell, LJ, Foster, H, Foster, K & Dickson, G 2011, 'Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice', Human Gene Therapy. https://doi.org/10.1089/hum.2011.020

Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice. / Koo, Taeyoung; Malerba, Alberto; Athanasopoulos, Takis et al.
In: Human Gene Therapy, 2011.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice

AU - Koo, Taeyoung

AU - Malerba, Alberto

AU - Athanasopoulos, Takis

AU - Trollet, Capucine

AU - Boldrin, Luisa

AU - Ferry, Arnaud

AU - Popplewell, Linda J

AU - Foster, Helen

AU - Foster, Keith

AU - Dickson, George

PY - 2011

Y1 - 2011

U2 - 10.1089/hum.2011.020

DO - 10.1089/hum.2011.020

M3 - Article

C2 - 21453126

SN - 1557-7422

JO - Human Gene Therapy

JF - Human Gene Therapy

ER -

Koo T, Malerba A, Athanasopoulos T, Trollet C, Boldrin L, Ferry A et al. Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice. Human Gene Therapy. 2011. doi: 10.1089/hum.2011.020