Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery. / Boitor, Radu; Kong, Kenny; Shipp, Dustin; Varma, Sandeep; Koloydenko, Alexey A.; Kulkarni, Kusum; Elsheikh, Somaia; Schut, Tom; Caspers, Peter; Puppels, Gerwin; van der Wolf, Martin; Sokolova, Elena; Nijsten, T.E.C.; Salence, Brogan; Williams, Hywel; Notingher, Ioan.

In: Biomedical Optics Express, Vol. 8, No. 12, 22.11.2017, p. 5749-5766.

Research output: Contribution to journalArticlepeer-review



  • Radu Boitor
  • Kenny Kong
  • Dustin Shipp
  • Sandeep Varma
  • Alexey A. Koloydenko
  • Kusum Kulkarni
  • Somaia Elsheikh
  • Tom Schut
  • Peter Caspers
  • Gerwin Puppels
  • Martin van der Wolf
  • Elena Sokolova
  • T.E.C. Nijsten
  • Brogan Salence
  • Hywel Williams
  • Ioan Notingher


We describe a multimodal spectral histopathology (MSH) prototype instrument combining two label-free optical techniques, tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), that allows detec
Original languageEnglish
Pages (from-to)5749-5766
Number of pages18
JournalBiomedical Optics Express
Issue number12
Publication statusPublished - 22 Nov 2017
This open access research output is licenced under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.

ID: 28895641