Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery

Radu Boitor; Kenny Kong; Dustin Shipp; Sandeep Varma; Alexey A. Koloydenko; Kusum Kulkarni; Somaia Elsheikh; Tom Schut; Peter Caspers; Gerwin Puppels; Martin van der Wolf; Elena Sokolova; T.E.C. Nijsten; Brogan Salence; Hywel Williams; Ioan Notingher

doi:10.1364/BOE.8.005749

Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery

Radu Boitor, Kenny Kong, Dustin Shipp, Sandeep Varma, Alexey A. Koloydenko, Kusum Kulkarni, Somaia Elsheikh, Tom Schut, Peter Caspers, Gerwin Puppels, Martin van der Wolf, Elena Sokolova, T.E.C. Nijsten, Brogan Salence, Hywel Williams, Ioan Notingher

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Abstract

We describe a multimodal spectral histopathology (MSH) prototype instrument combining two label-free optical techniques, tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), that allows detec

Original language	English
Pages (from-to)	5749-5766
Number of pages	18
Journal	Biomedical Optics Express
Volume	8
Issue number	12
DOIs	https://doi.org/10.1364/BOE.8.005749
Publication status	Published - 22 Nov 2017

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10.1364/BOE.8.005749Licence: CC BY

Accepted ManuscriptAccepted author manuscript, 7.01 MBLicence: CC BY

Cite this

Boitor, R., Kong, K., Shipp, D., Varma, S., Koloydenko, A. A., Kulkarni, K., Elsheikh, S., Schut, T., Caspers, P., Puppels, G., van der Wolf, M., Sokolova, E., Nijsten, T. E. C., Salence, B., Williams, H., & Notingher, I. (2017). Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery. Biomedical Optics Express, 8(12), 5749-5766. https://doi.org/10.1364/BOE.8.005749

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abstract = "We describe a multimodal spectral histopathology (MSH) prototype instrument combining two label-free optical techniques, tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), that allows detec",

author = "Radu Boitor and Kenny Kong and Dustin Shipp and Sandeep Varma and Koloydenko, {Alexey A.} and Kusum Kulkarni and Somaia Elsheikh and Tom Schut and Peter Caspers and Gerwin Puppels and {van der Wolf}, Martin and Elena Sokolova and T.E.C. Nijsten and Brogan Salence and Hywel Williams and Ioan Notingher",

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doi = "10.1364/BOE.8.005749",

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Boitor, R, Kong, K, Shipp, D, Varma, S, Koloydenko, AA, Kulkarni, K, Elsheikh, S, Schut, T, Caspers, P, Puppels, G, van der Wolf, M, Sokolova, E, Nijsten, TEC, Salence, B, Williams, H & Notingher, I 2017, 'Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery', Biomedical Optics Express, vol. 8, no. 12, pp. 5749-5766. https://doi.org/10.1364/BOE.8.005749

TY - JOUR

T1 - Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery

AU - Boitor, Radu

AU - Kong, Kenny

AU - Shipp, Dustin

AU - Varma, Sandeep

AU - Koloydenko, Alexey A.

AU - Kulkarni, Kusum

AU - Elsheikh, Somaia

AU - Schut, Tom

AU - Caspers, Peter

AU - Puppels, Gerwin

AU - van der Wolf, Martin

AU - Sokolova, Elena

AU - Nijsten, T.E.C.

AU - Salence, Brogan

AU - Williams, Hywel

AU - Notingher, Ioan

PY - 2017/11/22

Y1 - 2017/11/22

N2 - We describe a multimodal spectral histopathology (MSH) prototype instrument combining two label-free optical techniques, tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), that allows detec

AB - We describe a multimodal spectral histopathology (MSH) prototype instrument combining two label-free optical techniques, tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), that allows detec

U2 - 10.1364/BOE.8.005749

DO - 10.1364/BOE.8.005749

M3 - Article

SN - 2156-7085

VL - 8

SP - 5749

EP - 5766

JO - Biomedical Optics Express

JF - Biomedical Optics Express

IS - 12

ER -