Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit

D. J. Wyllie, A. R. Johnston, D. Lipscombe, P. E. Chen

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)477-89
Number of pages13
JournalJournal of Physiology
Issue numberPt 2
Publication statusPublished - 2006


  • Animals Cells, Cultured Female Gene Expression Regulation Glutamic Acid/metabolism Ion Channel Gating/*genetics/physiology Membrane Potentials/drug effects/physiology Oocytes/metabolism Patch-Clamp Techniques *Point Mutation Protein Binding/physiology Protein Structure, Tertiary/*genetics/physiology Receptors, N-Methyl-D-Aspartate/chemistry/*genetics/metabolism Serine/*analysis/physiology Xenopus laevis

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