Intramuscular injection of a plasmid vector expressing human apolipoprotein E limits progression of xanthoma and aortic atheroma in apoE-deficient mice

T Athanasopoulos, J S Owen, D Hassall, M G Dunckley, J Drew, J Goodman, A D Tagalakis, D R Riddell, G Dickson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2545-2551
Number of pages7
JournalHuman Molecular Genetics
Volume9
Issue number17
Publication statusPublished - 12 Oct 2000

Keywords

  • Animals
  • Apolipoprotein E2
  • Apolipoprotein E3
  • Apolipoproteins E
  • Arteriosclerosis
  • Cell Line
  • Disease Progression
  • Gene Expression
  • Gene Therapy
  • Gene Transfer Techniques
  • Genetic Vectors
  • Humans
  • Hyperlipidemias
  • Mice
  • Muscle, Skeletal
  • Plasmids
  • RNA, Messenger
  • Recombinant Proteins
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transfection
  • Xanthomatosis

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