Insertion of two independent enhancers in the long terminal repeat of a self-inactivating vector results in high-titer retroviral vectors with tissue-specific expression

A Fassati, A Bardoni, M Sironi, D J Wells, N Bresolin, G Scarlato, M Hatanaka, S Yamaoka, G Dickson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2459-68
Number of pages10
JournalHuman Gene Therapy
Issue number17
Publication statusPublished - 1998


  • 3T3 Cells
  • Animals
  • Base Sequence
  • Cell Line
  • DNA Primers
  • Enhancer Elements, Genetic
  • Gene Products, tax
  • Genes, Reporter
  • Genetic Complementation Test
  • Genetic Vectors
  • Human T-lymphotropic virus 1
  • Kanamycin Kinase
  • Lac Operon
  • Luciferases
  • Mice
  • Mice, Nude
  • Plasmids
  • Repetitive Sequences, Nucleic Acid
  • Retroviridae

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