Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E

J D Harris, S Schepelmann, T Athanasopoulos, I R Graham, A K Stannard, Z Mohri, V Hill, D G Hassall, J S Owen, G Dickson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)21-29
Number of pages9
JournalHuman Gene Therapy
Volume9
Issue number1
DOIs
Publication statusPublished - 31 Jan 2002

Keywords

  • gene therapy
  • apolipoprotein E
  • atherosclerosis
  • AAV
  • BONE-MARROW-TRANSPLANTATION
  • DIRECTED GENE-TRANSFER
  • COAGULATION FACTOR-IX
  • SEVERE HYPERCHOLESTEROLEMIA
  • INTRAMUSCULAR INJECTION
  • VIRAL VECTORS
  • CHOLESTEROL ACYLTRANSFERASE
  • CARDIOVASCULAR-DISEASE
  • TRANSGENE EXPRESSION
  • PLATELET-AGGREGATION

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