Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration

Olga Isman, Michael L Roberts, Jennifer E Morgan, Ian R Graham, Kirstin Goldring, Diana J Lawrence-Watt, Qi Long Lu, Matthew G Dunckley, Andrew C G Porter, Terence A Partridge, George Dickson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1000-8
Number of pages9
JournalHuman Gene Therapy
Volume19
Issue number10
DOIs
Publication statusPublished - 2008

Keywords

  • Adenoviridae
  • Animals
  • DNA Replication
  • Dermis
  • Dystrophin
  • Embryonic Stem Cells
  • Fibroblasts
  • Gene Targeting
  • Gene Therapy
  • Genetic Vectors
  • Humans
  • Mice
  • Mice, Inbred mdx
  • Muscular Dystrophy, Duchenne
  • Mutation
  • Myoblasts
  • Quantitative Trait Loci
  • Virus Integration

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