Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE

Julian D Harris, Ian R Graham, Silke Schepelmann, Anita K Stannard, Michael L Roberts, Bradley L Hodges, Vanessa Hill, Andrea Amalfitano, David G Hassall, James S Owen, George Dickson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)43-58
Number of pages16
JournalHuman Molecular Genetics
Issue number1
Publication statusPublished - 2002


  • Adenoviridae
  • Animals
  • Aorta
  • Apolipoproteins E
  • Arteriosclerosis
  • Blotting, Western
  • Cholesterol
  • DNA Primers
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Gene Transfer Techniques
  • Genetic Vectors
  • Humans
  • Lipids
  • Lipoproteins
  • Mice
  • Mice, Inbred C57BL
  • Mice, Mutant Strains
  • Muscle, Skeletal
  • Reverse Transcriptase Polymerase Chain Reaction

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