We theorized and tested the relationship of personal value systems with unethical attitudes and behavior. Results from three studies using 16 diverse multi-national samples (N = 107,087) demonstrated the complexity of motivations underlying unethicality. Across contexts and cultures, for attitudes (Study 1 meta-analysis) and behaviors in the lab (Study 2) and in real-life (Study 3), we consistently found that the values theory circumplex structure predicted the inhibition and motivation of unethicality. Unethicality was positively associated with self-enhancement values and negatively associated with self-transcendence and conservation values. However, self-transcendence and conservation values were associated with the inhibition of different types of unethicality. The relationship of openness-to-change values with unethicality was generally positive but the effect size varied depending on context.