Solar system bodies like comets, asteroids, meteorites and dust particles contain organic matter with different abundances, structures and chemical composition. This chapter compares the similarities and differences of the organic composition in these planetary bodies. Furthermore, these links are explored in the context of detecting the most pristine organic material, either by on-site analysis or sample return missions. Finally, we discuss the targets of potential future sample return missions, as well as the contamination controls that should be in place in order to successfully study pristine organic matter.