Metabolite Profiling : A Tool for the Biochemical Characterisation of Mycobacterium sp. / Drapal, Margit; Fraser, Paul.

In: Microorganisms, Vol. 7, No. 5, 148, 25.05.2019, p. 1-10.

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Metabolite Profiling : A Tool for the Biochemical Characterisation of Mycobacterium sp. / Drapal, Margit; Fraser, Paul.

In: Microorganisms, Vol. 7, No. 5, 148, 25.05.2019, p. 1-10.

Research output: Contribution to journalReview article

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@article{3618a0180f4a4a91b68ae1ab82dd7fd8,
title = "Metabolite Profiling: A Tool for the Biochemical Characterisation of Mycobacterium sp.",
abstract = "Over the last few decades, the occurrence of drug-resistance in Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, has increased in prevalence. These findings have rekindled interest in elucidating the unique adaptive molecular and biochemistry physiology of Mycobacterium. The use of metabolite profiling independently or in combination with other levels of “omic” analysis has proven an effective approach for the elucidation of key physiological/biochemical properties associated with Mtb throughout the infection. The following review will discuss the use of metabolite profiling in tuberculosis research, future approaches and the technical and logistical limitations of methodology to date.",
author = "Margit Drapal and Paul Fraser",
year = "2019",
month = may,
day = "25",
doi = "10.3390/microorganisms7050148",
language = "English",
volume = "7",
pages = "1--10",
journal = "Microorganisms",
issn = "2076-2607",
publisher = "MDPI AG",
number = "5",

}

RIS

TY - JOUR

T1 - Metabolite Profiling

T2 - A Tool for the Biochemical Characterisation of Mycobacterium sp.

AU - Drapal, Margit

AU - Fraser, Paul

PY - 2019/5/25

Y1 - 2019/5/25

N2 - Over the last few decades, the occurrence of drug-resistance in Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, has increased in prevalence. These findings have rekindled interest in elucidating the unique adaptive molecular and biochemistry physiology of Mycobacterium. The use of metabolite profiling independently or in combination with other levels of “omic” analysis has proven an effective approach for the elucidation of key physiological/biochemical properties associated with Mtb throughout the infection. The following review will discuss the use of metabolite profiling in tuberculosis research, future approaches and the technical and logistical limitations of methodology to date.

AB - Over the last few decades, the occurrence of drug-resistance in Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, has increased in prevalence. These findings have rekindled interest in elucidating the unique adaptive molecular and biochemistry physiology of Mycobacterium. The use of metabolite profiling independently or in combination with other levels of “omic” analysis has proven an effective approach for the elucidation of key physiological/biochemical properties associated with Mtb throughout the infection. The following review will discuss the use of metabolite profiling in tuberculosis research, future approaches and the technical and logistical limitations of methodology to date.

U2 - 10.3390/microorganisms7050148

DO - 10.3390/microorganisms7050148

M3 - Review article

VL - 7

SP - 1

EP - 10

JO - Microorganisms

JF - Microorganisms

SN - 2076-2607

IS - 5

M1 - 148

ER -