Impacts of undetected and inadequately treated hypertension on incident stroke in China. / Han, Thang ; Wang, Harry ; Wei, Li ; Pan, Yuesong ; Ying Ma, Ying Ma; Wang, Yu ; Wang, Jiaji ; Hu, Zhi ; Sharma, Pankaj; Chen, Ruoling .

In: BMJ Open, Vol. 7, No. 10, e016581, 08.10.2017, p. 1-9.

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E-pub ahead of print

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Impacts of undetected and inadequately treated hypertension on incident stroke in China. / Han, Thang ; Wang, Harry ; Wei, Li ; Pan, Yuesong ; Ying Ma, Ying Ma; Wang, Yu ; Wang, Jiaji ; Hu, Zhi ; Sharma, Pankaj; Chen, Ruoling .

In: BMJ Open, Vol. 7, No. 10, e016581, 08.10.2017, p. 1-9.

Research output: Contribution to journalArticlepeer-review

Harvard

Han, T, Wang, H, Wei, L, Pan, Y, Ying Ma, YM, Wang, Y, Wang, J, Hu, Z, Sharma, P & Chen, R 2017, 'Impacts of undetected and inadequately treated hypertension on incident stroke in China', BMJ Open, vol. 7, no. 10, e016581, pp. 1-9. https://doi.org/10.1136/bmjopen-2017-016581

APA

Han, T., Wang, H., Wei, L., Pan, Y., Ying Ma, Y. M., Wang, Y., Wang, J., Hu, Z., Sharma, P., & Chen, R. (2017). Impacts of undetected and inadequately treated hypertension on incident stroke in China. BMJ Open, 7(10), 1-9. [e016581]. https://doi.org/10.1136/bmjopen-2017-016581

Vancouver

Han T, Wang H, Wei L, Pan Y, Ying Ma YM, Wang Y et al. Impacts of undetected and inadequately treated hypertension on incident stroke in China. BMJ Open. 2017 Oct 8;7(10):1-9. e016581. https://doi.org/10.1136/bmjopen-2017-016581

Author

Han, Thang ; Wang, Harry ; Wei, Li ; Pan, Yuesong ; Ying Ma, Ying Ma ; Wang, Yu ; Wang, Jiaji ; Hu, Zhi ; Sharma, Pankaj ; Chen, Ruoling . / Impacts of undetected and inadequately treated hypertension on incident stroke in China. In: BMJ Open. 2017 ; Vol. 7, No. 10. pp. 1-9.

BibTeX

@article{ecf82953b348419db2e4022f730d4108,
title = "Impacts of undetected and inadequately treated hypertension on incident stroke in China",
abstract = "Objectives China carries the greatest burden of stroke given its largest volume of people with hypertension. This study assessed the impacts of suboptimal controls of hypertension on incident stroke and projected the number of patients with stroke saved after the control of blood pressure improved in population.Setting Anhui, China.Participants We examined data from the Anhui cohort of 2001–2011, consisting of 3336 participants aged ≥60 years who were randomly recruited from the urban and rural Anhui. 2852 participants (89.2%) had hypertensive status measured and no stroke at baseline, and were followed up until 2011 in three surveys using a standard method of interview.Results At baseline, 1646 participants (57.7%) were identified to have hypertension, among whom 912 (55.4%) were previously undetected, 115 (7.0%) detected but not treated, 452 (27.5%) treated but not controlled and only 127 (7.7%) controlled. During the 10-year follow-up, 211 incident stroke cases (12.8/1000 person-years) occurred. Compared with normotensive individuals at baseline, multivariate adjusted HR for having stroke increased in those with undetected hypertension by 1.63 (95%CI 1.15 to 2.32), untreated by 2.21 (1.26–3.85) and uncontrolled hypertension by 3.34 (2.28–4.88), but did not differ from those with controlled hypertension (1.34; 0.60–2.99). Based on a two-fold increase in the detection and management of current levels of hypertension and algorithms on the current situation in China, approximately 250 000 incident stroke cases could be prevented annually.Conclusions In China, hypertension is frequently undetected or inadequately treated. With appropriate management of hypertension, a substantial number of people could be saved form stroke.",
author = "Thang Han and Harry Wang and Li Wei and Yuesong Pan and {Ying Ma}, {Ying Ma} and Yu Wang and Jiaji Wang and Zhi Hu and Pankaj Sharma and Ruoling Chen",
year = "2017",
month = oct,
day = "8",
doi = "10.1136/bmjopen-2017-016581",
language = "English",
volume = "7",
pages = "1--9",
journal = "BMJ Open",
issn = "2044-6055",
publisher = "BMJ Publishing Group",
number = "10",

}

RIS

TY - JOUR

T1 - Impacts of undetected and inadequately treated hypertension on incident stroke in China

AU - Han, Thang

AU - Wang, Harry

AU - Wei, Li

AU - Pan, Yuesong

AU - Ying Ma, Ying Ma

AU - Wang, Yu

AU - Wang, Jiaji

AU - Hu, Zhi

AU - Sharma, Pankaj

AU - Chen, Ruoling

PY - 2017/10/8

Y1 - 2017/10/8

N2 - Objectives China carries the greatest burden of stroke given its largest volume of people with hypertension. This study assessed the impacts of suboptimal controls of hypertension on incident stroke and projected the number of patients with stroke saved after the control of blood pressure improved in population.Setting Anhui, China.Participants We examined data from the Anhui cohort of 2001–2011, consisting of 3336 participants aged ≥60 years who were randomly recruited from the urban and rural Anhui. 2852 participants (89.2%) had hypertensive status measured and no stroke at baseline, and were followed up until 2011 in three surveys using a standard method of interview.Results At baseline, 1646 participants (57.7%) were identified to have hypertension, among whom 912 (55.4%) were previously undetected, 115 (7.0%) detected but not treated, 452 (27.5%) treated but not controlled and only 127 (7.7%) controlled. During the 10-year follow-up, 211 incident stroke cases (12.8/1000 person-years) occurred. Compared with normotensive individuals at baseline, multivariate adjusted HR for having stroke increased in those with undetected hypertension by 1.63 (95%CI 1.15 to 2.32), untreated by 2.21 (1.26–3.85) and uncontrolled hypertension by 3.34 (2.28–4.88), but did not differ from those with controlled hypertension (1.34; 0.60–2.99). Based on a two-fold increase in the detection and management of current levels of hypertension and algorithms on the current situation in China, approximately 250 000 incident stroke cases could be prevented annually.Conclusions In China, hypertension is frequently undetected or inadequately treated. With appropriate management of hypertension, a substantial number of people could be saved form stroke.

AB - Objectives China carries the greatest burden of stroke given its largest volume of people with hypertension. This study assessed the impacts of suboptimal controls of hypertension on incident stroke and projected the number of patients with stroke saved after the control of blood pressure improved in population.Setting Anhui, China.Participants We examined data from the Anhui cohort of 2001–2011, consisting of 3336 participants aged ≥60 years who were randomly recruited from the urban and rural Anhui. 2852 participants (89.2%) had hypertensive status measured and no stroke at baseline, and were followed up until 2011 in three surveys using a standard method of interview.Results At baseline, 1646 participants (57.7%) were identified to have hypertension, among whom 912 (55.4%) were previously undetected, 115 (7.0%) detected but not treated, 452 (27.5%) treated but not controlled and only 127 (7.7%) controlled. During the 10-year follow-up, 211 incident stroke cases (12.8/1000 person-years) occurred. Compared with normotensive individuals at baseline, multivariate adjusted HR for having stroke increased in those with undetected hypertension by 1.63 (95%CI 1.15 to 2.32), untreated by 2.21 (1.26–3.85) and uncontrolled hypertension by 3.34 (2.28–4.88), but did not differ from those with controlled hypertension (1.34; 0.60–2.99). Based on a two-fold increase in the detection and management of current levels of hypertension and algorithms on the current situation in China, approximately 250 000 incident stroke cases could be prevented annually.Conclusions In China, hypertension is frequently undetected or inadequately treated. With appropriate management of hypertension, a substantial number of people could be saved form stroke.

U2 - 10.1136/bmjopen-2017-016581

DO - 10.1136/bmjopen-2017-016581

M3 - Article

VL - 7

SP - 1

EP - 9

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 10

M1 - e016581

ER -