High T-c SQUID systems for magnetophysiology

E. J. Tarte; P. E. Magnelind; A. Y. Tzalenchuk; A. Lohmus; D. A. Ansell; M. G. Blamire; Z. G. Ivanov; R. E. Dyball

High T-c SQUID systems for magnetophysiology

E. J. Tarte, P. E. Magnelind, A. Y. Tzalenchuk, A. Lohmus, D. A. Ansell, M. G. Blamire, Z. G. Ivanov, R. E. Dyball

Department of Physics

Research output: Contribution to journal › Article › peer-review

Abstract

Magnetophysiology is the use of a superconducting quantum interference device (SQUID) based instrument to detect neuromagnetic fields evoked by electrical stimulation of brain tissue slices. In this paper we show, that a SQUID based on high temperature superconductors (HTSs) would have considerable advantages over a low T-c device in this application. We construct a model of electrical activity in a hippocampal brain slice, which enables the neuromagnetic field to be determined as a function of position and distance from the tissue. We then describe the design of HTS SQUID systems for magnetophysiology and the two styles of system we are developing. Finally we use our model to show that an existing HTS SQUID magnetometer would give a superior signal to noise ratio compared to a low T-c system for the hippocampal brain slice preparation at least. (C) 2001 Published by Elsevier Science B.V.

Original language	English
Pages (from-to)	50-54
Number of pages	5
Journal	Physica C: Superconductivity and its Applications
Volume	368
Issue number	1-4
Publication status	Published - 2002

Cite this

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title = "High T-c SQUID systems for magnetophysiology",

abstract = "Magnetophysiology is the use of a superconducting quantum interference device (SQUID) based instrument to detect neuromagnetic fields evoked by electrical stimulation of brain tissue slices. In this paper we show, that a SQUID based on high temperature superconductors (HTSs) would have considerable advantages over a low T-c device in this application. We construct a model of electrical activity in a hippocampal brain slice, which enables the neuromagnetic field to be determined as a function of position and distance from the tissue. We then describe the design of HTS SQUID systems for magnetophysiology and the two styles of system we are developing. Finally we use our model to show that an existing HTS SQUID magnetometer would give a superior signal to noise ratio compared to a low T-c system for the hippocampal brain slice preparation at least. (C) 2001 Published by Elsevier Science B.V.",

author = "Tarte, {E. J.} and Magnelind, {P. E.} and Tzalenchuk, {A. Y.} and A. Lohmus and Ansell, {D. A.} and Blamire, {M. G.} and Ivanov, {Z. G.} and Dyball, {R. E.}",

year = "2002",

language = "English",

volume = "368",

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journal = "Physica C: Superconductivity and its Applications",

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TY - JOUR

T1 - High T-c SQUID systems for magnetophysiology

AU - Tarte, E. J.

AU - Magnelind, P. E.

AU - Tzalenchuk, A. Y.

AU - Lohmus, A.

AU - Ansell, D. A.

AU - Blamire, M. G.

AU - Ivanov, Z. G.

AU - Dyball, R. E.

PY - 2002

Y1 - 2002

N2 - Magnetophysiology is the use of a superconducting quantum interference device (SQUID) based instrument to detect neuromagnetic fields evoked by electrical stimulation of brain tissue slices. In this paper we show, that a SQUID based on high temperature superconductors (HTSs) would have considerable advantages over a low T-c device in this application. We construct a model of electrical activity in a hippocampal brain slice, which enables the neuromagnetic field to be determined as a function of position and distance from the tissue. We then describe the design of HTS SQUID systems for magnetophysiology and the two styles of system we are developing. Finally we use our model to show that an existing HTS SQUID magnetometer would give a superior signal to noise ratio compared to a low T-c system for the hippocampal brain slice preparation at least. (C) 2001 Published by Elsevier Science B.V.

AB - Magnetophysiology is the use of a superconducting quantum interference device (SQUID) based instrument to detect neuromagnetic fields evoked by electrical stimulation of brain tissue slices. In this paper we show, that a SQUID based on high temperature superconductors (HTSs) would have considerable advantages over a low T-c device in this application. We construct a model of electrical activity in a hippocampal brain slice, which enables the neuromagnetic field to be determined as a function of position and distance from the tissue. We then describe the design of HTS SQUID systems for magnetophysiology and the two styles of system we are developing. Finally we use our model to show that an existing HTS SQUID magnetometer would give a superior signal to noise ratio compared to a low T-c system for the hippocampal brain slice preparation at least. (C) 2001 Published by Elsevier Science B.V.

M3 - Article

SN - 1873-2143

VL - 368

SP - 50

EP - 54

JO - Physica C: Superconductivity and its Applications

JF - Physica C: Superconductivity and its Applications

IS - 1-4

ER -