Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer. / Foster, Helen; Sharp, Paul S; Athanasopoulos, Takis; Trollet, Capucine; Graham, Ian R; Foster, Keith; Wells, Dominic J; Dickson, George.

In: Molecular Therapy, Vol. 16, No. 11, 2008, p. 1825-32.

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Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer. / Foster, Helen; Sharp, Paul S; Athanasopoulos, Takis; Trollet, Capucine; Graham, Ian R; Foster, Keith; Wells, Dominic J; Dickson, George.

In: Molecular Therapy, Vol. 16, No. 11, 2008, p. 1825-32.

Research output: Contribution to journalArticlepeer-review

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@article{42e9b5892c9645c3b7d5c8e43383a525,
title = "Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer",
keywords = "Animals, Codon, Dependovirus, Dystrophin, Gene Transfer Techniques, Genetic Vectors, Humans, Mice, Mice, Inbred mdx, Muscular Dystrophy, Animal, RNA, Messenger, Transgenes",
author = "Helen Foster and Sharp, {Paul S} and Takis Athanasopoulos and Capucine Trollet and Graham, {Ian R} and Keith Foster and Wells, {Dominic J} and George Dickson",
year = "2008",
doi = "10.1038/mt.2008.186",
language = "English",
volume = "16",
pages = "1825--32",
journal = "Molecular Therapy",
issn = "1525-0016",
publisher = "Nature Publishing Group",
number = "11",

}

RIS

TY - JOUR

T1 - Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer

AU - Foster, Helen

AU - Sharp, Paul S

AU - Athanasopoulos, Takis

AU - Trollet, Capucine

AU - Graham, Ian R

AU - Foster, Keith

AU - Wells, Dominic J

AU - Dickson, George

PY - 2008

Y1 - 2008

KW - Animals

KW - Codon

KW - Dependovirus

KW - Dystrophin

KW - Gene Transfer Techniques

KW - Genetic Vectors

KW - Humans

KW - Mice

KW - Mice, Inbred mdx

KW - Muscular Dystrophy, Animal

KW - RNA, Messenger

KW - Transgenes

U2 - 10.1038/mt.2008.186

DO - 10.1038/mt.2008.186

M3 - Article

C2 - 18766174

VL - 16

SP - 1825

EP - 1832

JO - Molecular Therapy

JF - Molecular Therapy

SN - 1525-0016

IS - 11

ER -