Barriers to living donor kidney transplantation in the United Kingdom : a national observational study. / Wu, Diana; Robb, Matthew L; Watson, Christopher JE; Forsythe, John LR; Tomson, Charles RV; Cairns, John; Roderick, Paul; Johnson, Rachel J; Ravanan, Rommel; Fogarty, Damian; Bradley, Clare; Gibbons, Andrea; Metcalfe, Wendy ; Draper, Heather; Bradley, J Andrew ; Oniscu, Gabriel C.

In: Nephrology, Dialysis, Transplantation, Vol. 32, No. 5, 01.05.2017, p. 890–900.

Research output: Contribution to journalArticle

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Barriers to living donor kidney transplantation in the United Kingdom : a national observational study. / Wu, Diana; Robb, Matthew L; Watson, Christopher JE; Forsythe, John LR; Tomson, Charles RV; Cairns, John; Roderick, Paul; Johnson, Rachel J; Ravanan, Rommel; Fogarty, Damian; Bradley, Clare; Gibbons, Andrea; Metcalfe, Wendy ; Draper, Heather; Bradley, J Andrew ; Oniscu, Gabriel C.

In: Nephrology, Dialysis, Transplantation, Vol. 32, No. 5, 01.05.2017, p. 890–900.

Research output: Contribution to journalArticle

Harvard

Wu, D, Robb, ML, Watson, CJE, Forsythe, JLR, Tomson, CRV, Cairns, J, Roderick, P, Johnson, RJ, Ravanan, R, Fogarty, D, Bradley, C, Gibbons, A, Metcalfe, W, Draper, H, Bradley, JA & Oniscu, GC 2017, 'Barriers to living donor kidney transplantation in the United Kingdom: a national observational study', Nephrology, Dialysis, Transplantation, vol. 32, no. 5, pp. 890–900. https://doi.org/10.1093/ndt/gfx036

APA

Wu, D., Robb, M. L., Watson, C. JE., Forsythe, J. LR., Tomson, C. RV., Cairns, J., Roderick, P., Johnson, R. J., Ravanan, R., Fogarty, D., Bradley, C., Gibbons, A., Metcalfe, W., Draper, H., Bradley, J. A., & Oniscu, G. C. (2017). Barriers to living donor kidney transplantation in the United Kingdom: a national observational study. Nephrology, Dialysis, Transplantation, 32(5), 890–900. https://doi.org/10.1093/ndt/gfx036

Vancouver

Wu D, Robb ML, Watson CJE, Forsythe JLR, Tomson CRV, Cairns J et al. Barriers to living donor kidney transplantation in the United Kingdom: a national observational study. Nephrology, Dialysis, Transplantation. 2017 May 1;32(5):890–900. https://doi.org/10.1093/ndt/gfx036

Author

Wu, Diana ; Robb, Matthew L ; Watson, Christopher JE ; Forsythe, John LR ; Tomson, Charles RV ; Cairns, John ; Roderick, Paul ; Johnson, Rachel J ; Ravanan, Rommel ; Fogarty, Damian ; Bradley, Clare ; Gibbons, Andrea ; Metcalfe, Wendy ; Draper, Heather ; Bradley, J Andrew ; Oniscu, Gabriel C. / Barriers to living donor kidney transplantation in the United Kingdom : a national observational study. In: Nephrology, Dialysis, Transplantation. 2017 ; Vol. 32, No. 5. pp. 890–900.

BibTeX

@article{9157272c3e404dd497ecc7e5a54900e1,
title = "Barriers to living donor kidney transplantation in the United Kingdom: a national observational study",
abstract = "Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK.Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified.Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08–0.17], P < 0.0001 for 65–75 years versus 18–34 years}; Asian ethnicity [OR 0.55 (95% CI 0.39–0.77), P = 0.0006 versus White]; Black ethnicity [OR 0.64 (95% CI 0.42–0.99), P = 0.047 versus White]; divorced, separated or widowed [OR 0.63 (95% CI 0.46–0.88), P = 0.030 versus married]; no qualifications [OR 0.55 (95% CI 0.42–0.74), P < 0.0001 versus higher education qualifications]; no car ownership [OR 0.51 (95% CI 0.37–0.72), P = 0.0001] and no home ownership [OR 0.65 (95% CI 0.85–0.79), P = 0.002]. The odds of LDKT varied significantly between countries in the UK.Conclusions. Among patients undergoing kidney transplantation in the UK, there are significant age, ethnic, socio-economic and geographic disparities in the utilization of LDKT. Further work is needed to explore the potential for targeted interventions to improve equity in living donor transplantation.",
author = "Diana Wu and Robb, {Matthew L} and Watson, {Christopher JE} and Forsythe, {John LR} and Tomson, {Charles RV} and John Cairns and Paul Roderick and Johnson, {Rachel J} and Rommel Ravanan and Damian Fogarty and Clare Bradley and Andrea Gibbons and Wendy Metcalfe and Heather Draper and Bradley, {J Andrew} and Oniscu, {Gabriel C}",
year = "2017",
month = may,
day = "1",
doi = "10.1093/ndt/gfx036",
language = "English",
volume = "32",
pages = "890–900",
journal = "Nephrology, Dialysis, Transplantation",
issn = "0931-0509",
publisher = "Oxford University Press",
number = "5",

}

RIS

TY - JOUR

T1 - Barriers to living donor kidney transplantation in the United Kingdom

T2 - a national observational study

AU - Wu, Diana

AU - Robb, Matthew L

AU - Watson, Christopher JE

AU - Forsythe, John LR

AU - Tomson, Charles RV

AU - Cairns, John

AU - Roderick, Paul

AU - Johnson, Rachel J

AU - Ravanan, Rommel

AU - Fogarty, Damian

AU - Bradley, Clare

AU - Gibbons, Andrea

AU - Metcalfe, Wendy

AU - Draper, Heather

AU - Bradley, J Andrew

AU - Oniscu, Gabriel C

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK.Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified.Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08–0.17], P < 0.0001 for 65–75 years versus 18–34 years}; Asian ethnicity [OR 0.55 (95% CI 0.39–0.77), P = 0.0006 versus White]; Black ethnicity [OR 0.64 (95% CI 0.42–0.99), P = 0.047 versus White]; divorced, separated or widowed [OR 0.63 (95% CI 0.46–0.88), P = 0.030 versus married]; no qualifications [OR 0.55 (95% CI 0.42–0.74), P < 0.0001 versus higher education qualifications]; no car ownership [OR 0.51 (95% CI 0.37–0.72), P = 0.0001] and no home ownership [OR 0.65 (95% CI 0.85–0.79), P = 0.002]. The odds of LDKT varied significantly between countries in the UK.Conclusions. Among patients undergoing kidney transplantation in the UK, there are significant age, ethnic, socio-economic and geographic disparities in the utilization of LDKT. Further work is needed to explore the potential for targeted interventions to improve equity in living donor transplantation.

AB - Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK.Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified.Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08–0.17], P < 0.0001 for 65–75 years versus 18–34 years}; Asian ethnicity [OR 0.55 (95% CI 0.39–0.77), P = 0.0006 versus White]; Black ethnicity [OR 0.64 (95% CI 0.42–0.99), P = 0.047 versus White]; divorced, separated or widowed [OR 0.63 (95% CI 0.46–0.88), P = 0.030 versus married]; no qualifications [OR 0.55 (95% CI 0.42–0.74), P < 0.0001 versus higher education qualifications]; no car ownership [OR 0.51 (95% CI 0.37–0.72), P = 0.0001] and no home ownership [OR 0.65 (95% CI 0.85–0.79), P = 0.002]. The odds of LDKT varied significantly between countries in the UK.Conclusions. Among patients undergoing kidney transplantation in the UK, there are significant age, ethnic, socio-economic and geographic disparities in the utilization of LDKT. Further work is needed to explore the potential for targeted interventions to improve equity in living donor transplantation.

U2 - 10.1093/ndt/gfx036

DO - 10.1093/ndt/gfx036

M3 - Article

VL - 32

SP - 890

EP - 900

JO - Nephrology, Dialysis, Transplantation

JF - Nephrology, Dialysis, Transplantation

SN - 0931-0509

IS - 5

ER -