Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization

M Oliynyk, C B Stark, A Bhatt, MA Jones, Z A Hughes-Thomas, C Wilkinson, Z Oliynyk, Y Demydchuk, J Staunton, P F Leadlay

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1179-90
Number of pages12
JournalMol Microbiol
Volume49
Issue number5
Publication statusPublished - 2003

Keywords

  • Multienzyme Complexes Fatty Acid Synthetase Complex Gene Order Genes, Regulator Steroid Isomerases Gene Expression Regulation, Bacterial Thiolester Hydrolases Cyclization Oxidoreductases Molecular Sequence Data Monensin Epoxide Hydrolases Base Sequence Methyltransferases DNA, Bacterial Streptomyces Gene Deletion Mixed Function Oxygenases Oxidation-Reduction Genes, Bacterial Drug Resistance, Bacterial

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