Dr Stuart Snowden

  1. 2021
  2. Published

    Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease

    Whiley, L., Chappell, K., D'Hondt, E., Lewis, M., Jimenez, B., Snowden, S., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Swann, J., Hye, A., Lovestone, S., Legido-Quigley, C. & Holmes, E., 9 Jan 2021, In: Alzheimer's Research and Therapy. 13, 20.

    Research output: Contribution to journalArticlepeer-review

  3. E-pub ahead of print

    Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity

    Olga, L., van Diepen, JA., Bobeldijk-Pastorova, I., Gross, G., Prentice, PM., Snowden, S., Furse, S., Kooistra, T., Hughes, IA., Schoemaker, MH., van Tol, EAF., van Duyvenvoorde, W., Wielinga, PY., Ong, K. K., Dunger, DB., Kleemann, R. & Koulman, A., 7 Jan 2021, In: EbioMedicine. 63, 12 p., 103198.

    Research output: Contribution to journalArticlepeer-review

  4. 2020
  5. Published

    Development and Application of High-Throughput Single Cell Lipid Profiling: A Study of SNCA-A53T Human Dopamine Neurons

    Snowden, S. G., Fernandes, H. J. R., Kent, J., Foskolou, S., Tate, P., Field, S. F., Metzakopian, E. & Koulman, A., 20 Nov 2020, In: iScience. 23, 11, 31 p., 101703.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Combining lipidomics and machine learning to measure clinical lipids in dried blood spots

    Snowden, S., Korosi, A., de Rooji, S. & Koulman, A., 24 Jul 2020, In: Metabolomics. 16, 83.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders

    Ashton, N. J., Hye, A., Rajkumar, A. P., Leuzy, A., Snowden, S., Suárez-Calvet, M., Karikari, T. K., Schöll, M., La Joie, R., Rabinovici, G. D., Höglund, K. H., Ballard, C., Hortobágyi, T., Svenningsson, P., Blennow, K., Zetterberg, H. & Aarsland, D., May 2020, In: Nature Reviews Neurology. 16, p. 265-284 20 p.

    Research output: Contribution to journalArticlepeer-review

  8. 2019
  9. Published

    Neurotransmitter Imbalance in the Brain and Alzheimer’s Disease Pathology

    Snowden, S., Ebshiana, A. A., Hye, A., Pletnikova, O., O'Brien, R., Yang, A., Troncoso, J., Legido-Quigley, C. & Thambisetty, M., 29 Oct 2019, In: Journal of Alzheimer's Disease. 72, 1, p. 35-43 9 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism

    Furse, S., Snowden, S., Olga, L., Prentice, P., Ong, K. K., Hughes, I. A., Acerini, C. L., Dunger, D. B. & Koulman, A., 4 Oct 2019, In: Scientific Reports. 9, 10 p., 14321.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Relationship between the lipid composition of maternal plasma and infant plasma through breast milk

    Furse, S., Billing, G., Snowden, S., Smith, J., Goldberg, G. & Koulman, A., 25 Sep 2019, In: Metabolomics. 15, 129.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

    Kim, M., Snowden, S., Suvitaival, T., Ali, A., Merkler, D., Ahmad, T., Westwood, S., Baird, A., Proitsi, P., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S., Vandenberghe, R., Teunissen, C., Kate, M. T., Scheltens, P., Gabel, S., Meersmans, K., Blin, O. & 31 others, Richardson, J., De Roeck, E., Sleegers, K., Bordet, R., Rami, L., Kettunen, P., Tsolaki, M., Verhey, F., Sala, I., Lleo, A., Peyratout, G., tainta, M., Johannsen, P., Freund-Levi, Y., Frolich, L., Dobricic, V., Engelborghs, S., Frisoni, G., Molinuevo, J., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Barkhof, F., Ashton, N., Blennow, K., Zetterberg, H., Streffer, J., Visser, P., Lovestone, S. & Legido-Quigley, C., Jun 2019, In: Alzheimer's and Dementia. 15, 6, p. 817-827 11 p.

    Research output: Contribution to journalArticlepeer-review

  13. 2017
  14. Published

    Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease

    Kim, M., Nevado-Holgado, A., Whiley, L., Snowden, S., Soininen, H., Kloszewska, I., Mecocci, P., Toslaki, M., Vellas, B., Thambisetty, M., Dobson, R., Powell, J., Lupton, M., Simmons, A., Velayudhan, L., Lovestone, S., Proitsi, P. & Legido-Quigley, C., 3 Oct 2017, In: Journal of Alzheimer's Disease. 60, 3, p. 809-817 9 p.

    Research output: Contribution to journalArticlepeer-review

  15. E-pub ahead of print

    Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin–lysoPA axis in COPD

    Naz, S., Kolmert, J., Yang, M., Reinke, S. N., Kamleh, M. A., Snowden, S., Heyder, T., Levänen, B., Erle, D. J., Sköld, C. M., M. Wheelock, Å. & Wheelock, C. E., 22 Jun 2017, In: European Respiratory Journal. 49, 13 p., 1602322.

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

    Snowden, S., Ebshiana, A., Hye, A., An, Y., Pletnikova, O., O'Brien, R., Troncoso, J., Legido-Quigley, C. & Thambisetty, M., 21 Mar 2017, In: PLOS medicine. 14, 3, p. 1-19 19 p., e1002266.

    Research output: Contribution to journalArticlepeer-review

  17. 2016
  18. Published

    Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD

    Balgoma, D., Yang, M., Sjodin, M., Snowden, S., Snowden, S., Karimi, R., Levanen, B., Merikallio, H., Kaarteenaho, R., Palmberg, L., Larsson, K., Erle, D., Dahlen, S-E., Dahlen, B., Skold, M., Wheelock, A. & Wheelock, C., 31 May 2016, In: European Respiratory Journal. 47, 6, p. 1645-1656 12 p.

    Research output: Contribution to journalArticlepeer-review

  19. Published

    Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

    Chatterjee, P., Lim, W., Shui, G., Gupta, V., James, I., Fagan, A., Xiong, C., Sohrabi, H., Taddei, K., Brown, B., Benzinger, T., Masters, C., Snowden, S., Wenk, M., Bateman, R., Morris, J. & Martins, R., 2 Feb 2016, In: Journal of Alzheimer's Disease. 50, 3, p. 887-894 8 p.

    Research output: Contribution to journalArticlepeer-review

  20. 2015
  21. Published

    Metabolomic Method: UPLC-q-ToF Polar and Non-Polar Metabolites in the Healthy Rat Cerebellum Using an In-Vial Dual Extraction

    Ebshiana, A., Snowden, S., Thambisetty, M., Parsons, R., Hye, A. & Legido-Quigley, C., 8 Apr 2015, In: PLoS ONE. 10, 4, e0122883.

    Research output: Contribution to journalArticlepeer-review

  22. Published

    Metabolic Modifications in Human Biofluids Suggest the Involvement of Sphingolipid, Antioxidant, and Glutamate Metabolism in Alzheimer’s Disease Pathogenesis

    Ellis, B., Hye, A. & Snowden, S., 2015, In: Journal of Alzheimer's Disease. 46, 2, p. 313-327 15 p.

    Research output: Contribution to journalArticlepeer-review

  23. 2014
  24. Published

    LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNFα treatment

    Snowden, S., Kamleh, M. A., Grapov, D., Blackburn, G., Watson, D., Xu, N., Stahle, M. & Wheelock, C., 12 Nov 2014, In: Journal of Proteome Research. 14, 1, p. 557 566 p.

    Research output: Contribution to journalArticlepeer-review

  25. Published

    Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2

    van den Berk, L., Jansen, B., Snowden, S., Siebers-Vermeulen, K., Gilissen, C., Kogler, G., Figdor, C., Wheelock, C. & Torensma, R., 2014, In: Stem cells and Development. 14, p. 1582-1593

    Research output: Contribution to journalArticlepeer-review

  26. Published

    High-dose Simvastatin exhibits enhanced lipid-lowering effects relative to Simvastatin/Ezetimibe combination therapy

    Snowden, S., Grapov, D., Settergren, M., D'Alexandri, F. L., Haeggstrom, J., Fiehn, O., Hyotylainen, T., Pedersen, T., Newman, J., Oresic, M., Pernow, J. & Wheelock, C., 2014, In: Circulation and Cardivascular Genetics. 7, 6, p. 955-964

    Research output: Contribution to journalArticlepeer-review

  27. 2013
  28. Published

    Application of ‘omics technologies to biomarker discovery in inflammatory lung diseases

    Wheelock, C., Goss, V., Balgoma, D., Nicholas, B., Brandsma, J., Skipp, P., Snowden, S., Burg, D., D'Amico, A., Horvath, I., Chaiboonchoe, A., Ahmed, H., Ballereau, S., Rossios, C., Chung, K. F., Montuschi, P., Fowler, S., Adcock, I., Postle, A., Dahlen, S-E. & 4 others, Rowe, A., Sterk, P., Auffray, C. & Djukanovic, R., 2013, In: European Respiratory Journal. 42, p. 802-825

    Research output: Contribution to journalArticlepeer-review

  29. Published

    Dendritic cell reprogramming by endogenously produced lactic acid

    Nasi, A., Fekete, T., Krishnamurthy, A., Snowden, S., Rajnavolgyi, E., Catrina, A., Wheelock, C., Vivar, N. & Rethi, B., 2013, In: Journal of Immunology. 191, 6, p. 3090-3099

    Research output: Contribution to journalArticlepeer-review

  30. Published

    Quantitative metabolic profiling of lipid mediators

    Balgoma, D., Checa, A., Garcia Sar, D., Snowden, S. & Wheelock, C., 2013, In: Molecular Nutrition and Food Research . 57, 8, p. 1359-1377

    Research output: Contribution to journalArticlepeer-review

  31. 2012
  32. Published

    Application of metabolomics approaches to the study of respiratory diseases.

    Snowden, S., Dahlen, S-E. & Wheelock, C., 2012, In: Bioanalysis. 4, 18, p. 2265-2290

    Research output: Contribution to journalArticlepeer-review

  33. 2009
  34. Published

    Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour ‘rules’.

    Draper, J., Enot, D., Parker, D., Beckmann, M., Snowden, S., Lin, W. & Zubair, H., 2009, In: BMC Bioinformatics. 10, 227.

    Research output: Contribution to journalArticlepeer-review

  35. Published

    Metabolomic analysis reveals a common pattern of metabolic re-programming during invasion of three host plant species by Magnaporthe grisea

    Parker, D., Beckmann, M., Zubair, H., Enot, D., Caracuel-Rios, Z., Overy, D., Snowden, S., Talbot, N. & Draper, J., 2009, In: Plant Journal. 59, p. 723-737

    Research output: Contribution to journalArticlepeer-review