Professor Pankaj Sharma

  1. 2021
  2. Forthcoming

    Antiplatelet therapy in cardiovascular disease: current status and future directions

    Ferro, A., Passacquale, G., Sharma, P. & Perera, D., 22 Nov 2021, (Accepted/In press) In: British journal of clinical pharmacology.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Genome-wide association study identifies first locus associated with susceptibility to cerebral venous thrombosis

    International Stroke Genetics Consortium & Bio-Repository to Establish the Aetiology of Sinovenous Thrombosis (BEAST) collaborators, Nov 2021, In: Annals of Neurology. 90, 5, p. 777-788 12 p.

    Research output: Contribution to journalArticlepeer-review

  4. Forthcoming

    Predicting stroke complications in hospital and functional status at discharge by clustering of cardiovascular diseases a multi-centre registry-based study of acute stroke

    Han, T., Fry, C., Fluck, D., Gulli, G., Affley, B., Robin, J., Kakar, P. & Sharma, P., 4 Oct 2021, (Accepted/In press) In: Journal of Stroke & Cerebrovascular Diseases.

    Research output: Contribution to journalArticlepeer-review

  5. E-pub ahead of print

    Characteristics and Outcomes of Patients With Cerebral Venous Sinus Thrombosis in SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia

    Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group & Sharma, P., 28 Sep 2021, (E-pub ahead of print) In: JAMA neurology. 78, 11, p. 1314-1323 10 p.

    Research output: Contribution to journalArticlepeer-review

  6. Forthcoming

    Association of risk of malnutrition with adverse outcomes and early support on discharge in acute stroke patients without prestroke disability: a multi-centre registry-based cohort study

    Fluck, D., Fry, C., Gulli, G., Affley, B., Robin, J., Kakar, P., Sharma, P. & Han, T., 19 Sep 2021, (Accepted/In press) In: Nutrition in Clinical Practice.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Adverse consequences of immediate thrombolysis-related complications: a multi-centre registry-based cohort study of acute stroke

    Han, T., Gulli, G., Fry, C., Affley, B., Robin, J., Fluck, D., Kakar, P. & Sharma, P., 13 Jul 2021, In: Journal of Thrombosis and Thrombolysis.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Markov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples

    Ken Dror, G. & Sharma, P., 10 Jul 2021, In: Malaria Journal. 20, 311.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Outcome after acute ischemic stroke is linked to sex-specific lesion patterns

    Bonkhoff, A. & Sharma, P., 2 Jun 2021, In: Nature Communications. 12, 3289.

    Research output: Contribution to journalArticlepeer-review

  10. E-pub ahead of print

    Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India

    Kumar, A., Chauhan, G., Sharma, S., Dabla, S., Sylaja, P. N., Chaudhary, N., Gupta, S., Agrawal, C. S., Anand, K. S., Srivastava, A. K., Vibha, D., Sagar, R., Raj, R., Maheshwari, A., Vivekanandhan, S., Kaul, B., Raghavan, S., Gorthi, S. P., Mohania, D., Kaushik, S. & 4 others, Yadav, R. K., Hazarika, A., Sharma, P. & Prasad, K., 24 May 2021, (E-pub ahead of print) In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  11. E-pub ahead of print

    SARS-CoV-2 antibody seroprevalence in NHS healthcare workers in a large double-sited UK hospital

    Ken Dror, G., Wade, C., Sharma, S., Irvin-Sellers, M., Robin, J., Fluck, D., Bentley, P. & Sharma, P., 23 Mar 2021, (E-pub ahead of print) In: Clinical Medicine.

    Research output: Contribution to journalArticlepeer-review

  12. E-pub ahead of print

    Continuous positive airway pressure therapy reduces the levels of catecholamines and blood pressure in pseudophaeochromocytoma with coexisting obstructive sleep apnoea

    Ken Dror, G., Wood, M., Fluck, D., Sharma, P., Fry, C. & Han, T., 17 Mar 2021, (E-pub ahead of print) In: JRSM cardiovascular disease. 10

    Research output: Contribution to journalArticlepeer-review

  13. E-pub ahead of print

    The smoking-dyslipidaemia dyad: a potent synergistic risk for atherosclerotic coronary artery disease

    Prakash, V., Jaker, S., Jacques, A., Fluck, D., Sharma, P., Fry, C. & Han, T., 15 Mar 2021, (E-pub ahead of print) In: JRSM cardiovascular disease.

    Research output: Contribution to journalArticlepeer-review

  14. Forthcoming

    Twelve loci provide insights into the genetic basis of lacunar stroke and small vessel disease: a meta-analysis of genome-wide association studies

    Traylor, M. & Sharma, P., 15 Jan 2021, (Accepted/In press) In: Lancet Neurology.

    Research output: Contribution to journalArticlepeer-review

  15. 2020
  16. E-pub ahead of print

    Covid-19 outcomes in UK centre within highest health and wealth band: a prospective cohort study

    Ken Dror, G., Wade, C., Sharma, S., Law, J., Russo, C., Sharma, A., Joy, E., John, J., Robin, J., John, S., Mahana, K., Fluck, D., Bentley, P. & Sharma, P., 16 Nov 2020, (E-pub ahead of print) In: BMJ Open. 10, 11, e042090.

    Research output: Contribution to journalArticlepeer-review

  17. E-pub ahead of print

    Meta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnea

    Green, M., Ken-Dror, G., Fluck, D., Sada, C., Sharma, P., Fry, C. H. & Han, T. S., 24 Sep 2020, (E-pub ahead of print) In: Journal of Clinical Hypertension.

    Research output: Contribution to journalArticlepeer-review

  18. E-pub ahead of print

    Meta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnoea

    Green, M., Ken-Dror, G., Fluck, D., Sada, C., Sharma, P., Fry, C. & Han, T. S., 24 Sep 2020, (E-pub ahead of print) In: Journal of Clinical Hypertension.

    Research output: Contribution to journalArticlepeer-review

  19. Published
  20. E-pub ahead of print

    White matter hyperintensity burden in acute stroke patients differs by ischemic stroke subtype

    International Stroke Genetics Consortium & on behalf of the MRI-GENIE Investigators, 3 Jun 2020, (E-pub ahead of print) In: Neurology. 95, 1

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Whole-genome sequencing of a sporadic primary immunodeficiency cohort

    Sharma, P., 6 May 2020, In: Nature. p. 1-28 28 p.

    Research output: Contribution to journalArticlepeer-review

  22. Published

    Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke

    MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, May 2020, In: Mayo Clinic Proceedings. 95, 5, p. 955-965 11 p.

    Research output: Contribution to journalArticlepeer-review

  23. E-pub ahead of print

    Sex differences in the agreement between left ventricular ejection fraction measured by myocardial perfusion scintigraphy and by echocardiography

    Jaker, S., Burgan, A., Prakash, V., Birkinshaw, A., Moosai, K., Jacques, A., Fluck, D., MacGregor, M., Lazariashvili, O., Sharma, P., Fry, C. & Han, T., 24 Mar 2020, (E-pub ahead of print) In: JRSM cardiovascular disease. 9, p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  24. Published

    Progestogen-only pill associates with false-positive aldosterone/renin ratio screening test

    Birkinshaw, A., Sharma, P. & Han, T., Mar 2020, In: British Journal of Cardiology. 27, p. 37-40 4 p.

    Research output: Contribution to journalArticlepeer-review

  25. Published

    Prestroke Disability Predicts Adverse Poststroke Outcome: A Registry-Based Prospective Cohort Study of Acute Stroke

    Han, T. S., Fry, C. H., Gulli, G., Affley, B., Robin, J., Irvin-Sellers, M., Fluck, D., Kakar, P., Sharma, S. & Sharma, P., Feb 2020, In: Stroke. 51, 2, p. 594-600 7 p.

    Research output: Contribution to journalArticlepeer-review

  26. 2019
  27. Published

    Associations of 4AT with mobility, length of stay and mortality in hospital and discharge destination among patients admitted with hip fractures

    Lisk, R., Sharma, P. & Han, T., 8 Dec 2019, In: Age and Ageing. p. 1-7 7 p., afz161.

    Research output: Contribution to journalArticlepeer-review

  28. Published

    The role of virtual reality on outcomes in rehabilitation of Parkinson’s disease: meta-analysis and systematic review in 1031 participants

    Triegaardt, J., Han, T., Sada, C., Sharma, S. & Sharma, P., 6 Dec 2019, In: Neurological Sciences. p. 1-8 8 p.

    Research output: Contribution to journalArticlepeer-review

  29. E-pub ahead of print

    A clinical perspective of parathyroid hormone related hypercalcaemia

    Han, C., Fry, C., Sharma, P. & Han, T., 3 Dec 2019, (E-pub ahead of print) In: Reviews in Endocrine and Metabolic Disorders. p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  30. E-pub ahead of print

    Life Expectancy of White and Non-White Elite Heavyweight Boxers

    Han, T., Gabe, J., Sharma, P. & Lean, M., 3 Dec 2019, (E-pub ahead of print) In: Journal of Racial and Ethnic Health Disparities. p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  31. E-pub ahead of print

    Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study

    The Stroke Genetics Network (SiGN), The International Stroke Genetics Consortium (ISGC) & The MRI-Genetics Interface Exploration (MRI-GENIE) Study, 11 Nov 2019, (E-pub ahead of print) In: Journal of Neurology. p. 1-10 10 p.

    Research output: Contribution to journalArticlepeer-review

  32. E-pub ahead of print

    Secular trends in adiposity and musculoskeletal dimensions of elite heavyweight boxers between 1889 and 2019

    Han, T. & Sharma, P., 5 Nov 2019, (E-pub ahead of print) In: Sport Sciences for Health. p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

  33. E-pub ahead of print

    Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures

    Kelleher, J. & Sharma, P., 31 Oct 2019, (E-pub ahead of print) In: Stem Cell Reports. p. 1-15 15 p.

    Research output: Contribution to journalArticlepeer-review

  34. Published

    Prothrombin Complex Concentrates are Superior to Fresh Frozen Plasma for Emergency Reversal of Vitamin K Antagonists: A Meta-Analysis in 2606 Subjects

    Hill, R., Han, T., Lubormirova, I., Math, N., Bentley, P. & Sharma, P., Sep 2019, In: Drugs. 79, 14, p. 1557-1565 9 p.

    Research output: Contribution to journalArticlepeer-review

  35. E-pub ahead of print

    Current status of stroke in Qatar: Including data from the BRAINS study

    Jallow, E., Han, T., Sharma, S. & Sharma, P., 18 Aug 2019, (E-pub ahead of print) In: JRSM cardiovascular disease. 8, p. 1-13 13 p.

    Research output: Contribution to journalArticlepeer-review

  36. Published

    Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data

    Sharma, P., 1 Jul 2019, In: Stroke. 50, 7, p. 1734-1741 8 p.

    Research output: Contribution to journalArticlepeer-review

  37. E-pub ahead of print

    White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts – The MRI-GENIE study

    on behalf of the MRI-GENIE Investigators, 29 May 2019, (E-pub ahead of print) In: NeuroImage: Clinical. 23, p. 1-13 13 p., 101884.

    Research output: Contribution to journalArticlepeer-review

  38. Published

    Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

    Chauhan, G. & Sharma, P., 29 Jan 2019, In: Neurology. 92, 5, p. 1-19 19 p.

    Research output: Contribution to journalArticlepeer-review

  39. 2018
  40. Published

    GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    MEGASTROKE Consortium, 3 Dec 2018, In: Nature Communications. 9, p. 1-14 14 p., 5141.

    Research output: Contribution to journalArticlepeer-review

  41. Published

    A family with PTEN mutations with malignancy and an unusually high number of offspring with autism spectrum disorder: a case report

    Gruhl, S., Sharma, P. & Han, T., 28 Nov 2018, In: Journal of Medical Case Reports. 12, p. 1-6 6 p., 353.

    Research output: Contribution to journalArticlepeer-review

  42. Published

    Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

    Sharma, P., METASTROKE Consortium of the ISGC & WTCCC-2 Consortium , 1 Nov 2018, In: PLoS ONE. 13, 11, p. 1-12 12 p., e0206554.

    Research output: Contribution to journalArticlepeer-review

  43. E-pub ahead of print

    Predictive model of length of stay in hospital among older patients

    Lisk, R., Uddin, M., Parbhoo, A., Yeong, K., Fluck, D., Sharma, P., Lean, M. & Han, T., 6 Sep 2018, (E-pub ahead of print) In: Aging Clinical and Experimental Research . p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

  44. Published

    Non-genetic and genetic risk factors for adult cerebral venous thrombosis

    Green, M., Styles, T., Russell, T., Sada, C., Jallow, E., Stewart, J., Lazariashvili1, O., Cotlarciuc, I., Han, T. & Sharma, P., Sep 2018, In: Thrombosis Research. 169, p. 15-22 8 p.

    Research output: Contribution to journalArticlepeer-review

  45. E-pub ahead of print

    Incidence and prevalence of cardiovascular disease in English primary care: a cross-sectional and follow-up study of the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC)

    Hinton, W., McGovern, A., Coyle, R., Han, T., Sharma, P., Correa, A., Ferreira, F. & de Lusignan, S., 20 Aug 2018, (E-pub ahead of print) In: BMJ Open. 8, p. 1-9 9 p., e020282.

    Research output: Contribution to journalArticlepeer-review

  46. Published

    Analysis of shared heritability in common disorders of the brain

    Sharma, P., 22 Jun 2018, In: Science. 360, 6395, p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  47. Published

    Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

    Sharma, P. & Cotlarciuc, I., 1 Apr 2018, In: Nature Genetics. 50, p. 524–537 14 p.

    Research output: Contribution to journalArticlepeer-review

  48. Published

    Impact of delay in early swallow screening on pneumonia, length of stay in hospital, disability and mortality in acute stroke patients

    Han, T., Fluck, D., Lean, M., Affley, B., Gulli, G., Patel, T., Barrett, C., Kakar, P., Sharma, S. & Sharma, P., 27 Mar 2018, In: European Journal of Clinical Nutrition. 72, p. 1548–1554 7 p.

    Research output: Contribution to journalArticlepeer-review

  49. Published

    Motor dexterity and strength depend upon integrity of the attention-control system

    Rinne, P., Hassan, M., Fernandes, C., Han, E., Hennessy, E., Waldman, A., Sharma, P., Soto, D., Leech, R., Malhotra, P. & Bentley, P., 16 Jan 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 3, p. E536-E545 10 p.

    Research output: Contribution to journalArticlepeer-review

  50. Published

    Anticoagulation therapy in patients with stroke and atrial fibrillation: a registry-based study of acute stroke care in Surrey, UK

    Han, T., Fry, C. H., Fluck, D., Affley, B., Gulli, G., Barrett, C., Kakar, P., Patel, T., Sharma, S. & Sharma, P., 2018, In: BMJ Open. 8, 7, p. 1-8 8 p., e022558.

    Research output: Contribution to journalArticlepeer-review

  51. 2017
  52. Published

    Evaluation of anticoagulation status for atrial fibrillation on early ischaemic stroke outcomes: a registry-based, prospective cohort study of acute stroke care in Surrey, UK

    Han, T., Fry, C., Fluck, D., Affley, B., Gulli, G., Barrett, C., Kakar, P., Patel, T. & Sharma, P., 14 Dec 2017, In: BMJ Open. 7, 12, p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

  53. E-pub ahead of print

    Impacts of undetected and inadequately treated hypertension on incident stroke in China

    Han, T., Wang, H., Wei, L., Pan, Y., Ying Ma, Y. M., Wang, Y., Wang, J., Hu, Z., Sharma, P. & Chen, R., 8 Oct 2017, (E-pub ahead of print) In: BMJ Open. 7, 10, p. 1-9 9 p., e016581.

    Research output: Contribution to journalArticlepeer-review

  54. Published

    Design and rationale for examining neuroimaging genetics in ischemic stroke: The MRI-GENIE study

    Giese, A. K., Schirmer, M. D., Donahue, K. L., Cloonan, L., Irie, R., Winzeck, S., Bouts, M. J. R. J., McIntosh, E. C., Mocking, S. J., Dalca, A. V., Sridharan, R., Xu, H., Frid, P., Giralt-Steinhauer, E., Holmegaard, L., Roquer, J., Wasselius, J., Cole, J. W., McArdle, P. F., Broderick, J. P. & 21 others, Jimenez-Conde, J., Jern, C., Kissela, B. M., Kleindorfer, D. O., Lemmens, R., Lindgren, A., Meschia, J. F., Rundek, T., Sacco, R. L., Schmidt, R., Sharma, P., Slowik, A., Thijs, V., Woo, D., Worrall, B. B., Kittner, S. J., Mitchell, B. D., Rosand, J., Golland, P., Wu, O. & Rost, N. S., 1 Oct 2017, In: Neurology: Genetics. 3, 5

    Research output: Contribution to journalArticlepeer-review

  55. Published

    Monitoring risk factors of cardiovascular disease in cancer survivors

    Kapoor, A., Pakash, V., Sekhar, M., Greenfield, D., Hatton, M., Lean, M., Sharma, P. & Han, T., 1 Aug 2017, In: Clinical Medicine. 17, 4, p. 293-297 5 p.

    Research output: Contribution to journalArticlepeer-review

  56. E-pub ahead of print

    Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients

    Crompton, E., Lubormirova, I., Cotlarciuc, I., Han, T., Sharma, S. & Sharma, P., 1 Apr 2017, (E-pub ahead of print) In: Critical Care Medicine. 45, 4, p. 575-583 9 p.

    Research output: Contribution to journalArticlepeer-review

  57. Published

    Genetic Variation at 16q24.2 is associated with small vessel stroke

    Traylor, M., Malik, R., Nalls, M., Cotlarciuc, I., Radmanesh, F., Thorleifsson, G., Hanscombe, K., Langefeld, C., Saleheen, D., Rost, N., Yet, I., Spector, T., Bell, J., Hannon, E., Mill, J., Chauhan, G., Debette, S., Bis, J., Longstreth, WT., Ikram, A. & 47 others, Launer, L., Seshadri, S., Hamilton Bruce, M. A., Jimenez-Conde, J., Cole, J., Schmidt, R., Słowik, A., Lemmens, R., Lindgren, A., Melander, O., Grewal, R., Sacco, R., Rundek, T., Rexrode, K., Arnett, D., Johnson, J., Benavente, O., Wasssertheil-Smoller, S., Lee, J-M., Pulit, S., Wong, Q., Rich, S., de Bakker, P., McArdle, P., Woo, D., Anderson, C., Xu, H., Heitsch, L., Fornage, M., Jern, C., Stefansson, K., Thorsteinsdottir, U., Gretarsdottir, S., Lewis, C., Sharma, P., Sudlow, C., Rothwell, P., Boncoraglio, G., Thijs, V., Levi, C., Meschia, J., Rosand, J., Kittner, S., Mitchell, B., Dichgans, M., Worrall, B. & Markus, H., 25 Mar 2017, In: Annals of Neurology. 81, 3, p. 383–394 12 p.

    Research output: Contribution to journalArticlepeer-review

  58. 2016
  59. Published

    Towards the genetic basis of cerebral venous thrombosis—the BEAST Consortium: a study protocol

    Cotlarciuc, I., Marjot, T., Khan, M., Hiltunen, S., Haapaniemi, E., Metso, T., Putaala, J., Zuurbier, S., Brouwer, M., Passamonti, S., Bucciarelli, P., Pappalardo, E., Patel, T., Costa, P., Colombi, M., Canhão, P., Tkach, A., Santacroce, R., Margaglione, M., Favuzzi, G. & 17 others, Grandone, E., Colaizzo, D., Spengos, K., Arauz, A., Hodge, A., Ditta, R., Debette, S., Zedde, M., Pare, G., Ferro, J., Thijs, V., Pezzini, A., Majersik, J., Martinelli, I., Coutinho, J., Tatlisumak, T. & Sharma, P., 22 Nov 2016, In: BMJ Open. 6, 11, p. 1-6 6 p.

    Research output: Contribution to journalArticlepeer-review

  60. Published

    Democratizing Neurorehabilitation: How Accessible are Low-Cost Mobile-Gaming Technologies for Self-Rehabilitation of Arm Disability in Stroke?

    Rinne, P., Mace, M., Nakornchai, T., Zimmerman, K., Fayer, S., Sharma, P., Liardon, J-L., Burdet, E. & Bentley, P., 5 Oct 2016, In: PLoS ONE. 11, 10, p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  61. Published

    Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies

    Sharma, P. & The Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, the Stroke Genetics Network (SiGN), and the International Stroke Genetics Consortium (ISGC)†, Jun 2016, In: Lancet Neurology. 15, 7, p. 695–707 13 p.

    Research output: Contribution to journalArticlepeer-review

  62. Published

    Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration

    Malik, R., Traylor, M., Pulit, S. L., Bevan, S., Hopewell, J. C., Holliday, E. G., Zhao, W., Abrantes, P., Amouyel, P., Attia, J. R., Battey, T. W. K., Berger, K., Boncoraglio, G. B., Chauhan, G., Cheng, Y-C., Chen, W-M., Clarke, R., Cotlarciuc, I., Debette, S., Falcone, G. J. & 30 others, Ferro, J. M., Gamble, D. M., Ilinca, A., Kittner, S. J., Kourkoulis, C. E., Lemmens, R., Levi, C. R., Lichtner, P., Lindgren, A., Liu, J., Meschia, J. F., Mitchell, B. D., Oliveira, S. A., Pera, J., Reiner, A. P., Rothwell, P. M., Sharma, P., Slowik, A., Sudlow, C. L. M., Tatlisumak, T., Thijs, V., Vicente, A. M., Woo, D., Seshadri, S., Saleheen, D., Rosand, J., Markus, H. S., Worrall, B. B., Dichgans, M. & ISGC Analysis Group, 29 Mar 2016, In: Neurology. 86, 13, p. 1217-26 10 p.

    Research output: Contribution to journalArticlepeer-review

  63. Published

    Candidate-gene analysis of white matter hyperintensities on neuroimaging

    Tran, T., Cotlarciuc, I., Yadav, S., Hasan, N., Bentley, P., Levi, C., Worrall, B. B., Meschia, J. F., Rost, N. & Sharma, P., 14 Feb 2016, In: Journal of Neurology, Neurosurgery and Psychiatry. 87, 3, p. 260-266 7 p.

    Research output: Contribution to journalArticlepeer-review

  64. Published

    Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

    Keenan, T., Zhao, W., Rasheed, A., Ho, W. K., Malik, R., Felix, J. F., Young, R., Shah, N., Samuel, M., Sheikh, N., Mucksavage, M. L., Shah, O., Li, J., Morley, M., Laser, A., Mallick, N. H., Zaman, K. S., Ishaq, M., Rasheed, S. Z., Memon, F-U-R. & 37 others, Ahmed, F., Hanif, B., Lakhani, M. S., Fahim, M., Ishaq, M., Shardha, N. K., Ahmed, N., Mahmood, K., Iqbal, W., Akhtar, S., Raheel, R., O'Donnell, C. J., Hengstenberg, C., März, W., Kathiresan, S., Samani, N., Goel, A., Hopewell, J. C., Chambers, J., Cheng, Y-C., Sharma, P., Yang, Q., Rosand, J., Boncoraglio, G. B., Kazmi, S. U., Hakonarson, H., Köttgen, A., Kalogeropoulos, A., Frossard, P., Kamal, A., Dichgans, M., Cappola, T., Reilly, M. P., Danesh, J., Rader, D. J., Voight, B. F. & Saleheen, D., 2 Feb 2016, In: Journal of the American College of Cardiology. 67, 4, p. 407-16 10 p.

    Research output: Contribution to journalArticlepeer-review

  65. Published

    Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study

    NINDS Stroke Genetics Network (SiGN), Sharma, P. & Cotlarciuc, I., 1 Feb 2016, In: Lancet Neurology. 15, 2, p. 174–184 11 p.

    Research output: Contribution to journalArticlepeer-review

  66. Published

    Quantifying the risk of heart disease following acute ischaemic stroke: a meta-analysis of over 50,000 subjects

    Gunnoo, T., Hasan, N., Saleem Khan, M., Slark, J., Bentley, P. & Sharma, P., 20 Jan 2016, In: BMJ Open. 6, p. 1-7 7 p., e009535.

    Research output: Contribution to journalArticlepeer-review

  67. E-pub ahead of print

    Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2

    Cheng, Y-C., Stanne, T. M., Giese, A-K., Ho, W. K., Traylor, M., Amouyel, P., Holliday, E. G., Malik, R., Xu, H., Kittner, S. J., Cole, J. W., O’Connell, J. R., Danesh, J., Rasheed, A., Zhao, W., Engelter, S., Grond-Ginsbach, C., Kamatani, Y., Lathrop, M., Leys, D. & 43 others, Thijs, V., Metso, T. M., Tatlisumak, T., Pezzini, A., Parati, E. A., Norrving, B., Bevan, S., Rothwell, P. M., Sudlow, C., Slowik, A., Lindgren, A., Walters, M. R., Jannes, J., Shen, J., Crosslin, D., Doheny, K., Laurie, C. C., Kanse, S. M., Bis, J. C., Fornage, M., Mosley, T. H., Hopewell, J. C., Strauch, K., Müller-Nurasyid, M., Gieger, C., Waldenberger, M., Peters, A., Meisinger, C., Ikram, M. A., Longstreth, WT., Meschia, J. F., Seshadri, S., Sharma, P., Worrall, B., Jern, C., Levi, C., Dichgans, M., Boncoraglio, G. B., Markus, H. S., Debette, S., Rolfs, A., Saleheen, D. & Mitchell, B. D., 5 Jan 2016, (E-pub ahead of print) In: Stroke. 47, 2, p. 307-316 10 p.

    Research output: Contribution to journalArticlepeer-review

  68. 2015
  69. E-pub ahead of print

    Estimating Weight of Patients With Acute Stroke When Dosing for Thrombolysis

    Barrow, T., Khan, M. S., Halse, O., Bentley, P. & Sharma, P., 10 Nov 2015, (E-pub ahead of print) In: Stroke. 47, 1, p. 228-231 4 p.

    Research output: Contribution to journalArticlepeer-review

  70. Published

    Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants

    Malik, R., Freilinger, T., Winsvold, B. S., Anttila, V., Vander Heiden, J., Traylor, M., de Vries, B., Holliday, E. G., Terwindt, G. M., Sturm, J., Bis, J. C., Hopewell, J. C., Ferrari, M. D., Rannikmae, K., Wessman, M., Kallela, M., Kubisch, C., Fornage, M., Meschia, J. F., Lehtimäki, T. & 31 others, Sudlow, C., Clarke, R., Chasman, D. I., Mitchell, B. D., Maguire, J., Kaprio, J., Farrall, M., Raitakari, O. T., Kurth, T., Ikram, M. A., Reiner, A. P., Longstreth, W. T., Rothwell, P. M., Strachan, D. P., Sharma, P., Seshadri, S., Quaye, L., Cherkas, L., Schürks, M., Rosand, J., Ligthart, L., Boncoraglio, G. B., Davey Smith, G., van Duijn, C. M., Stefansson, K., Worrall, B. B., Nyholt, D. R., Markus, H. S., van den Maagdenberg, A. M. J. M., Cotsapas, C. & International Headache Genetics Consortium, 26 May 2015, In: Neurology. 84, 21, p. 2132-2145 14 p.

    Research output: Contribution to journalArticlepeer-review

  71. Published

    The Genetics of Ischaemic Stroke

    Yadav, S. & Sharma, P., 15 Apr 2015, In: Advances in Clinical Neuroscience and Rehabilitation. 15, 1, p. 6-12 7 p.

    Research output: Contribution to journalArticlepeer-review

  72. Published

    Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial

    CADISS trial investigators, Apr 2015, In: Lancet Neurology. 14, 4, p. 361-367 7 p.

    Research output: Contribution to journalArticlepeer-review

  73. Published

    Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

    Rannikmäe, K., Davies, G., Thomson, P. A., Bevan, S., Devan, W. J., Falcone, G. J., Traylor, M., Anderson, C. D., Battey, T. W. K., Radmanesh, F., Deka, R., Woo, J. G., Martin, L. J., Jimenez-Conde, J., Selim, M., Brown, D. L., Silliman, S. L., Kidwell, C. S., Montaner, J., Langefeld, C. D. & 31 others, Slowik, A., Hansen, B. M., Lindgren, A. G., Meschia, J. F., Fornage, M., Bis, J. C., Debette, S., Ikram, M. A., Longstreth, W. T., Schmidt, R., Zhang, C. R., Yang, Q., Sharma, P., Kittner, S. J., Mitchell, B. D., Holliday, E. G., Levi, C. R., Attia, J., Rothwell, P. M., Poole, D. L., Boncoraglio, G. B., Psaty, B. M., Malik, R., Rost, N., Worrall, B. B., Dichgans, M., Van Agtmael, T., Woo, D., Markus, H. S., Seshadri, S. & METASTROKE Consortium, the CHARGE WMH Group, the ISGC ICH GWAS Study Collaboration, the WMH in Ischemic Stroke GWAS Study Collaboration, and the International Stroke Genetics Consortium, 3 Mar 2015, In: Neurology. 84, 9, p. 918-926 9 p.

    Research output: Contribution to journalArticlepeer-review

  74. Published

    Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke

    Holliday, E. G., Traylor, M., Malik, R., Bevan, S., Falcone, G., Hopewell, J. C., Cheng, Y-C., Cotlarciuc, I., Bis, J. C., Boerwinkle, E., Boncoraglio, G. B., Clarke, R., Cole, J. W., Fornage, M., Furie, K. L., Ikram, M. A., Jannes, J., Kittner, S. J., Lincz, L. F., Maguire, J. M. & 21 others, Meschia, J. F., Mosley, T. H., Nalls, M. A., Oldmeadow, C., Parati, E. A., Psaty, B. M., Rothwell, P. M., Seshadri, S., Scott, R. J., Sharma, P., Sudlow, C., Wiggins, K. L., Worrall, B. B., Rosand, J., Mitchell, B. D., Dichgans, M., Markus, H. S., Levi, C., Attia, J., Wray, N. R. & Australian Stroke Genetics Collaborative, the Wellcome Trust Case Control Consortium 2, and the International Stroke Genetics Consortium, Mar 2015, In: Stroke; a journal of cerebral circulation. 46, 3, p. 615-619 5 p.

    Research output: Contribution to journalArticlepeer-review

  75. Published

    Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection

    Debette, S., Kamatani, Y., Metso, T. M., Kloss, M., Chauhan, G., Engelter, S. T., Pezzini, A., Thijs, V., Markus, H. S., Dichgans, M., Wolf, C., Dittrich, R., Touzé, E., Southerland, A. M., Samson, Y., Abboud, S., Béjot, Y., Caso, V., Bersano, A., Gschwendtner, A. & 50 others, Sessa, M., Cole, J., Lamy, C., Medeiros, E., Beretta, S., Bonati, L. H., Grau, A. J., Michel, P., Majersik, J. J., Sharma, P., Kalashnikova, L., Nazarova, M., Dobrynina, L., Bartels, E., Guillon, B., van den Herik, E. G., Fernandez-Cadenas, I., Jood, K., Nalls, M. A., De Leeuw, F-E., Jern, C., Cheng, Y-C., Werner, I., Metso, A. J., Lichy, C., Lyrer, P. A., Brandt, T., Boncoraglio, G. B., Wichmann, H-E., Gieger, C., Johnson, A. D., Böttcher, T., Castellano, M., Arveiler, D., Ikram, M. A., Breteler, M. M. B., Padovani, A., Meschia, J. F., Kuhlenbäumer, G., Rolfs, A., Worrall, B. B., International Stroke Genetics Consortium, Ringelstein, E-B., Zelenika, D., Tatlisumak, T., Lathrop, M., Leys, D., the CADISP group, Amouyel, P. & Dallongeville, J., Jan 2015, In: Nature Genetics. 47, p. 78-83 6 p.

    Research output: Contribution to journalArticlepeer-review

  76. 2014
  77. Published

    Agreement between TOAST and CCS ischemic stroke classification: the NINDS SiGN study

    McArdle, P. F., Kittner, S. J., Ay, H., Brown, R. D., Meschia, J. F., Rundek, T., Wassertheil-Smoller, S., Woo, D., Andsberg, G., Biffi, A., Brenner, D. A., Cole, J. W., Corriveau, R., de Bakker, P. I. W., Delavaran, H., Dichgans, M., Grewal, R. P., Gwinn, K., Huq, M., Jern, C. & 27 others, Jimenez-Conde, J., Jood, K., Kaplan, R. C., Katschnig, P., Katsnelson, M., Labovitz, D. L., Lemmens, R., Li, L., Lindgren, A., Markus, H. S., Peddareddygari, L. R., Pedersén, A., Pera, J., Redfors, P., Roquer, J., Rosand, J., Rost, N. S., Rothwell, P. M., Sacco, R. L., Sharma, P., Slowik, A., Sudlow, C., Thijs, V., Tiedt, S., Valenti, R., Worrall, B. B. & NINDS SiGN Study, 28 Oct 2014, In: Neurology. 83, 18, p. 1653-60 8 p.

    Research output: Contribution to journalArticlepeer-review

  78. Published

    Lesion locations influencing baseline severity and early recovery in ischaemic stroke

    Bentley, P., Kumar, G., Rinne, P., Buddha, S., Kallingal, J., Hookway, C., Sharma, P., Mehta, A. & Beckmann, C., Sep 2014, In: European journal of neurology : the official journal of the European Federation of Neurological Societies. 21, 9, p. 1226-32 7 p.

    Research output: Contribution to journalArticlepeer-review

  79. Published

    Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12

    Kilarski, L. L., Achterberg, S., Devan, W. J., Traylor, M., Malik, R., Lindgren, A., Pare, G., Sharma, P., Slowik, A., Thijs, V., Walters, M., Worrall, B. B., Sale, M. M., Algra, A., Kappelle, L. J., Wijmenga, C., Norrving, B., Sandling, J. K., Rönnblom, L., Goris, A. & 29 others, Franke, A., Sudlow, C., Rothwell, P. M., Levi, C., Holliday, E. G., Fornage, M., Psaty, B., Gretarsdottir, S., Thorsteinsdottir, U., Seshadri, S., Mitchell, B. D., Kittner, S., Clarke, R., Hopewell, J. C., Bis, J. C., Boncoraglio, G. B., Meschia, J., Ikram, M. A., Hansen, B. M., Montaner, J., Thorleifsson, G., Stefanson, K., Rosand, J., de Bakker, P. I. W., Farrall, M., Dichgans, M., Markus, H. S., Bevan, S. & GARNET Collaborative Research Group, Wellcome Trust Case Control Consortium 2, Australian Stroke Genetic Collaborative, the METASTROKE Consortium, and the International Stroke Genetics Consortium, 19 Aug 2014, In: Neurology. 83, 8, p. 678-85 8 p.

    Research output: Contribution to journalArticlepeer-review

  80. Published

    Increased platelet expression of glycoprotein IIIa following aspirin treatment in aspirin-resistant but not aspirin-sensitive subjects

    Floyd, C. N., Goodman, T., Becker, S., Chen, N., Mustafa, A., Schofield, E., Campbell, J., Ward, M., Sharma, P. & Ferro, A., Aug 2014, In: British journal of clinical pharmacology. 78, 2, p. 320-8 9 p.

    Research output: Contribution to journalArticlepeer-review

  81. Published

    Knowledge of blood pressure in a U.K. general public population

    Slark, J., Khan, M. S., Bentley, P. & Sharma, P., Aug 2014, In: Journal of human hypertension. 28, 8, p. 500-3 4 p.

    Research output: Contribution to journalArticlepeer-review

  82. Published

    A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

    Traylor, M., Mäkelä, K-M., Kilarski, L. L., Holliday, E. G., Devan, W. J., Nalls, M. A., Wiggins, K. L., Zhao, W., Cheng, Y-C., Achterberg, S., Malik, R., Sudlow, C., Bevan, S., Raitoharju, E., Oksala, N., Thijs, V., Lemmens, R., Lindgren, A., Slowik, A., Maguire, J. M. & 19 others, Walters, M., Algra, A., Sharma, P., Attia, J. R., Boncoraglio, G. B., Rothwell, P. M., de Bakker, P. I. W., Bis, J. C., Saleheen, D., Kittner, S. J., Mitchell, B. D., Rosand, J., Meschia, J. F., Levi, C., Dichgans, M., Lehtimäki, T., Lewis, C. M., Markus, H. S. & METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2), Jul 2014, In: PLoS genetics. 10, 7, p. e1004469

    Research output: Contribution to journalArticlepeer-review

  83. Published

    Effect of genetic variants associated with plasma homocysteine levels on stroke risk

    Cotlarciuc, I., Malik, R., Holliday, E. G., Ahmadi, K. R., Paré, G., Psaty, B. M., Fornage, M., Hasan, N., Rinne, P. E., Ikram, M. A., Markus, H. S., Rosand, J., Mitchell, B. D., Kittner, S. J., Meschia, J. F., van Meurs, J. B. J., Uitterlinden, A. G., Worrall, B. B., Dichgans, M., Sharma, P. & 1 others, METASTROKE and the International Stroke Genetics Consortium, Jul 2014, In: Stroke; a journal of cerebral circulation. 45, 7, p. 1920-4 5 p.

    Research output: Contribution to journalArticlepeer-review

  84. Published

    Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

    Malik, R., Bevan, S., Nalls, M. A., Holliday, E. G., Devan, W. J., Cheng, Y-C., Ibrahim-Verbaas, C. A., Verhaaren, B. F. J., Bis, J. C., Joon, A. Y., de Stefano, A. L., Fornage, M., Psaty, B. M., Ikram, M. A., Launer, L. J., van Duijn, C. M., Sharma, P., Mitchell, B. D., Rosand, J., Meschia, J. F. & 7 others, Levi, C., Rothwell, P. M., Sudlow, C., Markus, H. S., Seshadri, S., Dichgans, M. & Wellcome Trust Case Control Consortium 2, Feb 2014, In: Stroke; a journal of cerebral circulation. 45, 2, p. 394-402 9 p.

    Research output: Contribution to journalArticlepeer-review

  85. Published

    Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

    Dichgans, M., Malik, R., König, I. R., Rosand, J., Clarke, R., Gretarsdottir, S., Thorleifsson, G., Mitchell, B. D., Assimes, T. L., Levi, C., O'Donnell, C. J., Fornage, M., Thorsteinsdottir, U., Psaty, B. M., Hengstenberg, C., Seshadri, S., Erdmann, J., Bis, J. C., Peters, A., Boncoraglio, G. B. & 20 others, März, W., Meschia, J. F., Kathiresan, S., Ikram, M. A., McPherson, R., Stefansson, K., Sudlow, C., Reilly, M. P., Thompson, J. R., Sharma, P., Hopewell, J. C., Chambers, J. C., Watkins, H., Rothwell, P. M., Roberts, R., Markus, H. S., Samani, N. J., Farrall, M., Schunkert, H. & METASTROKE Consortium, Jan 2014, In: Stroke; a journal of cerebral circulation. 45, 1, p. 24-36 13 p.

    Research output: Contribution to journalArticlepeer-review

  86. Forthcoming

    Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network

    Ay, H., Arsava, E. M., Andsberg, G., Benner, T., Brown, R., Chapman Smith, S., Cole, J., Delavaran, H., Dichgans, M., Engström, G., Giralt-Steinhauer, E., Grewal, R., Gwinn, K., Jern, C., Jimenez-Conde, J., Jood, K., Katsnelson, M., Kissela, B., Kittner, S., Kleindorfer, D. & 34 others, Labovitz, D., Lanfranconi, S., Lee, J-M., Lehm, M., Lemmens, R., Levi, C., Li, L., Lindgren, A., Markus, H., McArdle, P., Melander, O., Norrving, B., Reddy Peddareddygari, L., Pedersen, A., Pera, J., Rannikmäe, K., Rexrode, K., Rhodes, J., Rich, S., Roquer, J., Rosand, J., Rothwell, P., Rundek, T., Sacco, R., Schmidt, R., Schürks, M., Seiler, S., Sharma, P., Slowik, A., Sudlow, C., N Thijs, V., Woodfield, R., Worrall, B. & Meschia, J., 2014, (Accepted/In press) In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  87. Published

    Prediction of stroke thrombolysis outcome using CT brain machine learning

    Bentley, P., Ganesalingam, J., Carlton Jones, A. L., Mahady, K., Epton, S., Rinne, P., Sharma, P., Halse, O., Mehta, A. & Rueckert, D., 2014, In: NeuroImage. Clinical. 4, p. 635-40 6 p.

    Research output: Contribution to journalArticlepeer-review

  88. 2013
  89. Published

    Genome-wide analysis of blood pressure variability and ischemic stroke

    Yadav, S., Cotlarciuc, I., Munroe, P. B., Khan, M. S., Nalls, M. A., Bevan, S., Cheng, Y-C., Chen, W-M., Malik, R., McCarthy, N. S., Holliday, E. G., Speed, D., Hasan, N., Pucek, M., Rinne, P. E., Sever, P., Stanton, A., Shields, D. C., Maguire, J. M., McEvoy, M. & 15 others, Scott, R. J., Ferrucci, L., Macleod, M. J., Attia, J., Markus, H. S., Sale, M. M., Worrall, B. B., Mitchell, B. D., Dichgans, M., Sudlow, C., Meschia, J. F., Rothwell, P. M., Caulfield, M., Sharma, P. & International Stroke Genetics Consortium, Oct 2013, In: Stroke; a journal of cerebral circulation. 44, 10, p. 2703-9 7 p.

    Research output: Contribution to journalArticlepeer-review

  90. Published

    Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes

    Meschia, J. F., Arnett, D. K., Ay, H., Brown, R. D., Benavente, O. R., Cole, J. W., de Bakker, P. I. W., Dichgans, M., Doheny, K. F., Fornage, M., Grewal, R. P., Gwinn, K., Jern, C., Conde, J. J., Johnson, J. A., Jood, K., Laurie, C. C., Lee, J-M., Lindgren, A., Markus, H. S. & 21 others, McArdle, P. F., McClure, L. A., Mitchell, B. D., Schmidt, R., Rexrode, K. M., Rich, S. S., Rosand, J., Rothwell, P. M., Rundek, T., Sacco, R. L., Sharma, P., Shuldiner, A. R., Slowik, A., Wassertheil-Smoller, S., Sudlow, C., Thijs, V. N. S., Woo, D., Worrall, B. B., Wu, O., Kittner, S. J. & NINDS SiGN Study, Oct 2013, In: Stroke; a journal of cerebral circulation. 44, 10, p. 2694-702 9 p.

    Research output: Contribution to journalArticlepeer-review

  91. Published

    Triple dissociation of attention networks in stroke according to lesion location

    Rinne, P., Hassan, M., Goniotakis, D., Chohan, K., Sharma, P., Langdon, D., Soto, D. & Bentley, P., 27 Aug 2013, In: Neurology. 81, 9, p. 812-20 9 p.

    Research output: Contribution to journalArticlepeer-review

  92. 2012
  93. Published

    Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

    Holliday, E. G., Maguire, J. M., Evans, T-J., Koblar, S. A., Jannes, J., Sturm, J. W., Hankey, G. J., Baker, R., Golledge, J., Parsons, M. W., Malik, R., McEvoy, M., Biros, E., Lewis, M. D., Lincz, L. F., Peel, R., Oldmeadow, C., Smith, W., Moscato, P., Barlera, S. & 31 others, Bevan, S., Bis, J. C., Boerwinkle, E., Boncoraglio, G. B., Brott, T. G., Brown, R. D., Cheng, Y-C., Cole, J. W., Cotlarciuc, I., Devan, W. J., Fornage, M., Furie, K. L., Grétarsdóttir, S., Gschwendtner, A., Ikram, M. A., Longstreth, W. T., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Parati, E. A., Psaty, B. M., Sharma, P., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Traylor, M., Verhaaren, B. F. J., Wiggins, K. L., Worrall, B. B. & Australian Stroke Genetics Collaborative, Oct 2012, In: Nature Genetics. 44, 10, p. 1147-51 5 p.

    Research output: Contribution to journalArticlepeer-review

  94. Published

    Bio-repository of DNA in stroke: a study protocol of three ancestral populations

    Cotlarciuc, I., Khan, M. S., Maheshwari, A., Yadav, S., Khan, F. Y., Al-Hail, H., de Silva, R., Gorthi, S. P., Gupta, S., Sharma, S. R., Sylaja, P. N., Prasad, K. & Sharma, P., 2012, In: JRSM cardiovascular disease. 1, 4

    Research output: Contribution to journalArticlepeer-review