1. 2021
  2. Forthcoming

    Efficacy of mirror therapy and virtual reality therapy in alleviating phantom limb pain: a meta-analysis and systematic review

    Rajendram, C., Ken Dror, G., Han, T. & Sharma, P., 28 Dec 2021, (Accepted/In press) In: BMJ Military Health.

    Research output: Contribution to journalArticlepeer-review

  3. Forthcoming

    Sex-specific lesion topographies explain outcomes after acute ischemic stroke

    MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, 20 Dec 2021, (Accepted/In press) In: Brain Communications.

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Restoration of Normal NF1 Function with Antisense Morpholino Treatment of Recurrent Pathogenic Patient-Specific Variant c.1466A>G; p.Y489C

    Awad, E., Moore, M., Liu, H., Ciszewski, L., Lambert, L., Korf, B. R., Popplewell, L., Kesterson, R. & Wallis, D., 7 Dec 2021, In: Journal of Personalized Medicine. 11, 12, 1320.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2

    Chaytow, H., Sethw Hassan, I., Akbar, S., Popplewell, L., Dickson, G. & Chen, P., 1 Dec 2021, In: Journal of Neuroscience Methods. 364, 109357.

    Research output: Contribution to journalArticlepeer-review

  6. Forthcoming

    Antiplatelet therapy in cardiovascular disease: current status and future directions

    Ferro, A., Passacquale, G., Sharma, P. & Perera, D., 22 Nov 2021, (Accepted/In press) In: British journal of clinical pharmacology.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Genome-wide association study identifies first locus associated with susceptibility to cerebral venous thrombosis

    International Stroke Genetics Consortium & Bio-Repository to Establish the Aetiology of Sinovenous Thrombosis (BEAST) collaborators, Nov 2021, In: Annals of Neurology. 90, 5, p. 777-788 12 p.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Decanoic Acid Stimulates Autophagy in D. discoideum

    Warren, E., Kramar, P., Lloyd-Jones, K. & Williams, R. S., 29 Oct 2021, In: Cells. 10, 11, 15 p., 2946.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Predicting stroke complications in hospital and functional status at discharge by clustering of cardiovascular diseases a multi-centre registry-based study of acute stroke

    Han, T., Fry, C., Fluck, D., Gulli, G., Affley, B., Robin, J., Kakar, P. & Sharma, P., 22 Oct 2021, In: Journal of Stroke & Cerebrovascular Diseases. 31, 1, 106162.

    Research output: Contribution to journalArticlepeer-review

  10. E-pub ahead of print

    Association of risk of malnutrition with adverse outcomes and early support on discharge in acute stroke patients without prestroke disability: a multicenter, registry-based cohort study

    Fluck, D., Fry, C., Gulli, G., Affley, B., Robin, J., Kakar, P., Sharma, P. & Han, T., 19 Oct 2021, (E-pub ahead of print) In: Nutrition in Clinical Practice.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Assessing Fast Structure Formation Processes in Isotactic Polypropylene with a Combination of Nanofocus X-ray Diffraction and In Situ Nanocalorimetry

    Odarchenko, Y., Rosenthal, M., Hernandez, J. J., Doblas, D., Di Cola, E., Soloviev, M. & Ivanov, D. A., 9 Oct 2021, In: Nanomaterials. 11, 10, 2652.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Systematic review and meta-analysis determining the benefits of in vivo genetic therapy in spinal muscular atrophy rodent models

    Chilcott, E., Muiruri, E., Hirst, T. C. & Yáñez-Muñoz, R. J., 6 Oct 2021, In: Gene Therapy.

    Research output: Contribution to journalArticlepeer-review

  13. E-pub ahead of print

    Characteristics and Outcomes of Patients With Cerebral Venous Sinus Thrombosis in SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia

    Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group & Sharma, P., 28 Sep 2021, (E-pub ahead of print) In: JAMA neurology. 78, 11, p. 1314-1323 10 p.

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Using Dictyostelium to advance our understanding of the role of medium chain fatty acids in health and disease

    Pain, E., Shinhmar, S. & Williams, R. S., 13 Sep 2021, In: Frontiers in Cell and Developmental Biology. 9, 722066.

    Research output: Contribution to journalLiterature reviewpeer-review

  15. Published

    Micellar Antibiotics of Bacillus

    Ferreira, W., Huynh, H., Hess, M., Adams, J., Wood, H., Bakun, K., Tan, S., Baccigalupi, L., Ferrari, E., Brisson, A., Ricca, E., Rejas, M. T., Meijer, W., Soloviev, M. & Cutting, S., 19 Aug 2021, In: Pharmaceutics . 13, 8, 1296.

    Research output: Contribution to journalArticlepeer-review

  16. Published

    K.Vita: a feasibility study of a blend of medium chain triglycerides to manage drug-resistant epilepsy

    Schoeler, N., Orford, M., Vivekananda, U., Simpson, Z., Van de Bor, B., Smith, H., Balestrini, S., Rutherford, T., Brennan, E., McKenna, J., Lambert, B., Barker, T., Jackson, R., Williams, R. S., Sisodiya, S., Eaton, S., Heales, S., Cross, J. H. & Walker, M., 23 Jul 2021, In: Brain Communications. fcab160.

    Research output: Contribution to journalArticlepeer-review

  17. Published

    Adverse consequences of immediate thrombolysis-related complications: a multi-centre registry-based cohort study of acute stroke

    Han, T., Gulli, G., Fry, C., Affley, B., Robin, J., Fluck, D., Kakar, P. & Sharma, P., 13 Jul 2021, In: Journal of Thrombosis and Thrombolysis.

    Research output: Contribution to journalArticlepeer-review

  18. Published

    Markov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples

    Ken Dror, G. & Sharma, P., 10 Jul 2021, In: Malaria Journal. 20, 311.

    Research output: Contribution to journalArticlepeer-review

  19. Published

    Outcome after acute ischemic stroke is linked to sex-specific lesion patterns

    Bonkhoff, A. & Sharma, P., 2 Jun 2021, In: Nature Communications. 12, 3289.

    Research output: Contribution to journalArticlepeer-review

  20. E-pub ahead of print

    Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India

    Kumar, A., Chauhan, G., Sharma, S., Dabla, S., Sylaja, P. N., Chaudhary, N., Gupta, S., Agrawal, C. S., Anand, K. S., Srivastava, A. K., Vibha, D., Sagar, R., Raj, R., Maheshwari, A., Vivekanandhan, S., Kaul, B., Raghavan, S., Gorthi, S. P., Mohania, D., Kaushik, S. & 4 others, Yadav, R. K., Hazarika, A., Sharma, P. & Prasad, K., 24 May 2021, (E-pub ahead of print) In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  21. Published

    RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

    Gudiño, V., Pohl, S. Ö-G., Billard, C. V., Cammareri, P., Bolado, A., Aitken, S., Stevenson, D., Hall, A. E., Agostino, M., Cassidy, J., Nixon, C., von Kriegsheim, A., Freile, P., Popplewell, L., Dickson, G., Murphy, L., Wheeler, A., Dunlop, M., Din, F., Strathdee, D. & 2 others, Sansom, O. J. & Myant, K. B., 20 Apr 2021, In: Nature Communications. 12, 1, 2335.

    Research output: Contribution to journalArticlepeer-review

  22. E-pub ahead of print

    Dose-dependent microdystrophin expression enhancement in cardiac muscle by a cardiac specific regulatory element

    Malerba, A., Sidoli, C., Lu-Nguyen, N. B., Herath, S., Le Heron, A., Abdul-Razak, H., Jarmin, S., Vandendriessche, T., Chuah, M. K. L., Dickson, G. & Popplewell, L. J., 26 Mar 2021, (E-pub ahead of print) In: Human Gene Therapy.

    Research output: Contribution to journalArticlepeer-review

  23. E-pub ahead of print

    Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies

    Traylor, M. & Sharma, P., 25 Mar 2021, (E-pub ahead of print) In: Lancet Neurology. 20, 5, p. 351-161 11 p.

    Research output: Contribution to journalArticlepeer-review

  24. E-pub ahead of print

    SARS-CoV-2 antibody seroprevalence in NHS healthcare workers in a large double-sited UK hospital

    Ken Dror, G., Wade, C., Sharma, S., Irvin-Sellers, M., Robin, J., Fluck, D., Bentley, P. & Sharma, P., 23 Mar 2021, (E-pub ahead of print) In: Clinical Medicine.

    Research output: Contribution to journalArticlepeer-review

  25. E-pub ahead of print

    Continuous positive airway pressure therapy reduces the levels of catecholamines and blood pressure in pseudophaeochromocytoma with coexisting obstructive sleep apnoea

    Ken Dror, G., Wood, M., Fluck, D., Sharma, P., Fry, C. & Han, T., 17 Mar 2021, (E-pub ahead of print) In: JRSM cardiovascular disease. 10

    Research output: Contribution to journalArticlepeer-review

  26. E-pub ahead of print

    The smoking-dyslipidaemia dyad: a potent synergistic risk for atherosclerotic coronary artery disease

    Prakash, V., Jaker, S., Jacques, A., Fluck, D., Sharma, P., Fry, C. & Han, T., 15 Mar 2021, (E-pub ahead of print) In: JRSM cardiovascular disease.

    Research output: Contribution to journalArticlepeer-review

  27. Published

    Phytocannabinoid-dependent mTORC1 regulation is dependent upon IPMK activity

    Damstra-Oddy, J., Warren, E., Perry, C., Desfougères, Y., Fitzpatrick, J-M. K., Schaf, J., Costelloe, L., Hind, W., Downer, E. J., Saiardi, A. & Williams BSc PhD FRSB, R. SB., Mar 2021, In: British Journal of Pharmacology. 178, 5, p. 1149-1163 15 p.

    Research output: Contribution to journalArticlepeer-review

  28. Published

    Thermo-responsive tag for on demand release of immobilized proteins

    Saccardo, A., Soloviev, M. & Ferrari, E., 11 Jan 2021.

    Research output: Contribution to conferenceOther

  29. 2020
  30. E-pub ahead of print

    Covid-19 outcomes in UK centre within highest health and wealth band: a prospective cohort study

    Ken Dror, G., Wade, C., Sharma, S., Law, J., Russo, C., Sharma, A., Joy, E., John, J., Robin, J., John, S., Mahana, K., Fluck, D., Bentley, P. & Sharma, P., 16 Nov 2020, (E-pub ahead of print) In: BMJ Open. 10, 11, e042090.

    Research output: Contribution to journalArticlepeer-review

  31. Published

    Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome

    Iqbal, A., Baldrighi, M., Murdoch, J., Fleming, A. & Wilkinson, C., 5 Oct 2020, In: Biology Open. 9, 10, p. 1-10 10 p., bio054338.

    Research output: Contribution to journalArticlepeer-review

  32. E-pub ahead of print

    Meta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnea

    Green, M., Ken-Dror, G., Fluck, D., Sada, C., Sharma, P., Fry, C. H. & Han, T. S., 24 Sep 2020, (E-pub ahead of print) In: Journal of Clinical Hypertension.

    Research output: Contribution to journalArticlepeer-review

  33. E-pub ahead of print

    Meta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnoea

    Green, M., Ken-Dror, G., Fluck, D., Sada, C., Sharma, P., Fry, C. & Han, T. S., 24 Sep 2020, (E-pub ahead of print) In: Journal of Clinical Hypertension.

    Research output: Contribution to journalArticlepeer-review

  34. Published

    Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling

    Warren, E., Dooves, S., Lugara, E., Damstra-Oddy, J., Schaf, J., Heine, V., Walker, M. & Williams BSc PhD FRSB, R. SB., 22 Sep 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 38, p. 23617-23625 9 p.

    Research output: Contribution to journalArticlepeer-review

  35. E-pub ahead of print

    Structural basis of AMPA receptor inhibition by trans‐4‐butylcyclohexane carboxylic acid

    Yelshanskaya, M., Singh, A., Narangoda, C., Williams BSc PhD FRSB, R. SB., Kurnikova, M. & Sobolevsky, A., 22 Sep 2020, (E-pub ahead of print) In: British Journal of Pharmacology.

    Research output: Contribution to journalArticlepeer-review

  36. E-pub ahead of print

    The Saturation Game: Teaching Protein–Ligand Binding with a Playing Card Analogy

    McEvoy, J. & Kay, A., 1 Sep 2020, (E-pub ahead of print) In: Journal of Chemical Education. 4 p.

    Research output: Contribution to journalArticlepeer-review

  37. Published

    Loss of both CDKN2A and CDKN2B allows for centrosome overduplication in melanoma

    Patel, S., Wilkinson, C. & Sviderskaya, E., Sep 2020, In: Journal of Investigative Dermatology. 140, 9, p. 1837-1846.e1 11 p.

    Research output: Contribution to journalArticlepeer-review

  38. Published
  39. Published

    Mutation-Directed Therapeutics for Neurofibromatosis Type I

    Leier, A., Bedwell, D. M., Chen, A. T., Dickson, G., Keeling, K. M., Kesterson, R. A., Korf, B. R., Marquez Lago, T. T., Müller, U. F., Popplewell, L., Zhou, J. & Wallis, D., 5 Jun 2020, In: Molecular therapy. Nucleic acids. 20, p. 739-753 15 p.

    Research output: Contribution to journalReview articlepeer-review

  40. E-pub ahead of print

    White matter hyperintensity burden in acute stroke patients differs by ischemic stroke subtype

    International Stroke Genetics Consortium & on behalf of the MRI-GENIE Investigators, 3 Jun 2020, (E-pub ahead of print) In: Neurology. 95, 1

    Research output: Contribution to journalArticlepeer-review

  41. Published

    Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile

    Whittingham, J. L., Hanai, S., Brannigan, J. A., Ferreira, W. T., Dodson, E. J., Turkenburg, J. P., Cartwright, J., Cutting, S. M. & Wilkinson, A. J., Jun 2020, In: Acta crystallographica. Section F, Structural biology communications. 76, 6, p. 241-249 9 p.

    Research output: Contribution to journalArticlepeer-review

  42. Published

    Whole-genome sequencing of a sporadic primary immunodeficiency cohort

    Sharma, P., 6 May 2020, In: Nature. p. 1-28 28 p.

    Research output: Contribution to journalArticlepeer-review

  43. Published

    Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke

    MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, May 2020, In: Mayo Clinic Proceedings. 95, 5, p. 955-965 11 p.

    Research output: Contribution to journalArticlepeer-review

  44. Published

    From pKa to the pH of weak base solutions

    McEvoy, J., May 2020, In: Biochemistry and Molecular Biology Education. p. 1-3 3 p.

    Research output: Contribution to journalArticlepeer-review

  45. Published

    Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice

    Ahlskog, N., Hayler-Pountney, D., Krueger, A., Kubinski, S., Claus, P., Hammond, S. M., Wood, M. J. A., Yáñez-Muñoz, R. J. & Bowerman, M., 20 Apr 2020, In: Gene Therapy. p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  46. E-pub ahead of print

    A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins

    Saccardo, A., Soloviev, M. & Ferrari, E., 1 Apr 2020, (E-pub ahead of print) In: Biomaterials science. 8, 9, p. 2673-2681 9 p.

    Research output: Contribution to journalArticlepeer-review

  47. E-pub ahead of print

    A Dictyostelium discoideum mitochondrial fluorescent tagging vector that does not affect respiratory function

    Perry, C., Warren, E., Oddy, J., Storey, C., Francione, L., annesley, S., Fisher, P., Muller-Taubenberger, A. & Williams BSc PhD FRSB, R. SB., 25 Mar 2020, (E-pub ahead of print) In: Biochemistry and Biophysics Reports. 22, p. 1-5 5 p., 100751.

    Research output: Contribution to journalArticlepeer-review

  48. Published

    G-quadruplex ligands mediate downregulation of DUX4 expression

    Ciszewski, L., Lu-Nguyen, N., Slater, A., Brennan, A., Williams, H. E. L., Dickson, G., Searle, M. S. & Popplewell, L., 17 Mar 2020, In: Nucleic Acids Research. 48, 8, p. 4179-4194 16 p., gkaa146.

    Research output: Contribution to journalArticlepeer-review

  49. E-pub ahead of print

    Directed and Modular Protein Immobilization on Gold and Silver Nanoparticles

    Saccardo, A., Ma, W., Soloviev, M. & Ferrari, E., 10 Mar 2020, (E-pub ahead of print) In: Methods in Molecular Biology. 2118, p. 227-234 8 p.

    Research output: Contribution to journalArticlepeer-review

  50. E-pub ahead of print

    Oriented Immobilization on Gold Nanoparticles of a Recombinant Therapeutic Zymogen

    Dosadina, E., Agyeiwaa, C., Ferreira, W., Cutting, S., Jibawi, A., Ferrari, E. & Soloviev, M., 10 Mar 2020, (E-pub ahead of print) In: Methods in Molecular Biology. 2118, p. 213-225 13 p.

    Research output: Contribution to journalArticlepeer-review

  51. E-pub ahead of print

    Protein Immobilization on Gold Nanoparticles: Quantitative Analysis

    Decker, E., Bai, C., Nelless, L., Ferrari, E. & Soloviev, M., 10 Mar 2020, (E-pub ahead of print) In: Methods in Molecular Biology. 2118, p. 199-211 13 p.

    Research output: Contribution to journalArticlepeer-review

  52. E-pub ahead of print

    Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy

    on behalf of the SKIP-NMD Study Group, 5 Mar 2020, (E-pub ahead of print) In: Neurology. 94, 21, p. e2270-e2282 13 p.

    Research output: Contribution to journalArticlepeer-review

  53. Published

    Inhibition of Myostatin Reduces Collagen Deposition in a Mouse Model of Oculopharyngeal Muscular Dystrophy (OPMD) With Established Disease

    Harish, P., Forrest, L., Herath, S., Dickson, G., Malerba, A. & Popplewell, L., 5 Mar 2020, In: Frontiers in Physiology. 11, p. 1-8 8 p., 184.

    Research output: Contribution to journalArticlepeer-review

  54. Published

    Progestogen-only pill associates with false-positive aldosterone/renin ratio screening test

    Birkinshaw, A., Sharma, P. & Han, T., Mar 2020, In: British Journal of Cardiology. 27, p. 37-40 4 p.

    Research output: Contribution to journalArticlepeer-review

  55. Published

    A new mechanism for cannabidiol in regulating the one‐carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models

    Perry, C., Finch, P., Muller-Taubenberger, A., Leung, K-Y., Warren, E., Damstra-Oddy, J., Sharma, D., patra, P., glyn, S., boberska, J., Stewart, B., baldwin, A., piscitelli, F., Harvey, R., harwood, A., Thompson, C., claus, S., Greene, N., McNeish, A., williams, C. & 2 others, whalley, B. & Williams, R., Feb 2020, In: British Journal of Pharmacology. 177, 4, p. 912-928 17 p.

    Research output: Contribution to journalArticlepeer-review

  56. Published

    Prestroke Disability Predicts Adverse Poststroke Outcome: A Registry-Based Prospective Cohort Study of Acute Stroke

    Han, T. S., Fry, C. H., Gulli, G., Affley, B., Robin, J., Irvin-Sellers, M., Fluck, D., Kakar, P., Sharma, S. & Sharma, P., Feb 2020, In: Stroke. 51, 2, p. 594-600 7 p.

    Research output: Contribution to journalArticlepeer-review

  57. Published

    Antimicrobial Applications of Silver Nanoparticles to E. coli Colony Biofilms

    McEvoy, J., Genc, K., Loi, P. & Walker, W. J., 2020, Nanoparticles in Biology and Medicine. Ferrari, E. & Soloviev, M. (eds.). Springer, p. 21-28 (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  58. 2019
  59. E-pub ahead of print

    Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction

    Pegge, J., Tatsinkam, A. J., Rider, C. C. & Bell, E., 25 Dec 2019, (E-pub ahead of print) In: Developmental Biology. p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

  60. Published

    Associations of 4AT with mobility, length of stay and mortality in hospital and discharge destination among patients admitted with hip fractures

    Lisk, R., Sharma, P. & Han, T., 8 Dec 2019, In: Age and Ageing. p. 1-7 7 p., afz161.

    Research output: Contribution to journalArticlepeer-review

  61. Published

    The role of virtual reality on outcomes in rehabilitation of Parkinson’s disease: meta-analysis and systematic review in 1031 participants

    Triegaardt, J., Han, T., Sada, C., Sharma, S. & Sharma, P., 6 Dec 2019, In: Neurological Sciences. p. 1-8 8 p.

    Research output: Contribution to journalArticlepeer-review

  62. E-pub ahead of print

    A clinical perspective of parathyroid hormone related hypercalcaemia

    Han, C., Fry, C., Sharma, P. & Han, T., 3 Dec 2019, (E-pub ahead of print) In: Reviews in Endocrine and Metabolic Disorders. p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

  63. E-pub ahead of print

    Life Expectancy of White and Non-White Elite Heavyweight Boxers

    Han, T., Gabe, J., Sharma, P. & Lean, M., 3 Dec 2019, (E-pub ahead of print) In: Journal of Racial and Ethnic Health Disparities. p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  64. Published

    Biofilms facilitate cheating and social exploitation of β-lactam resistance in Escherichia coli

    Amanatidou, E., Matthews, A., Kuhlicke, U., Neu, T., McEvoy, J. & Raymond, B., 29 Nov 2019, In: npj Biofilms and Microbiomes. 5, p. 1-10 10 p., 36.

    Research output: Contribution to journalArticlepeer-review

  65. E-pub ahead of print

    Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study

    The Stroke Genetics Network (SiGN), The International Stroke Genetics Consortium (ISGC) & The MRI-Genetics Interface Exploration (MRI-GENIE) Study, 11 Nov 2019, (E-pub ahead of print) In: Journal of Neurology. p. 1-10 10 p.

    Research output: Contribution to journalArticlepeer-review

  66. E-pub ahead of print

    Secular trends in adiposity and musculoskeletal dimensions of elite heavyweight boxers between 1889 and 2019

    Han, T. & Sharma, P., 5 Nov 2019, (E-pub ahead of print) In: Sport Sciences for Health. p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

  67. E-pub ahead of print

    Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures

    Kelleher, J. & Sharma, P., 31 Oct 2019, (E-pub ahead of print) In: Stem Cell Reports. p. 1-15 15 p.

    Research output: Contribution to journalArticlepeer-review

  68. Published

    Single-tube, dual channel pentaplexing for the identification of Candida strains associated with human infection

    Jainlabdin, M. H., Batra, A., Sánchez Paredes, E., Hernández Hernández, F., Fu, G. & Tovar-Torres, J., 11 Oct 2019, In: Scientific Reports. 9, p. 1-14 14 p., 14692.

    Research output: Contribution to journalArticlepeer-review

  69. Published

    Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knock-down and replacement of mutant expanded PABPN1

    Malerba, A., Klein, P., Lu-Nguyen, N., Cappellari, O., Strings-Ufombah, V., Harbaran, S., Roelvink, P., Suhy, D., Trollet, C. & Dickson, G., 1 Oct 2019, In: Human Molecular Genetics. p. 1-24 24 p., ddz167.

    Research output: Contribution to journalArticlepeer-review

  70. Published

    A study to assess a novel automated electrocardiogram technology in screening for atrial fibrillation

    Sabar, M. I., Ara, F., Henderson, A., Ahmed, O., Potter, C., John, I., Mitchell, A. R. J., Yáñez-Muñoz, R. J. & Kaba, R. A., Oct 2019, In: Pacing and clinical electrophysiology : PACE. 42, 10, p. 1383-1389 7 p.

    Research output: Contribution to journalArticlepeer-review

  71. Published

    Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD)

    Harish, P., Malerba, A., Lu-Nguyen, N., Forrest, L., Cappellari, O., Roth, F., Trollet, C., Popplewell, L. & Dickson, G., Oct 2019, In: Journal of Cachexia, Sarcopenia and Muscle. 10, 5, p. 1016-1026 11 p.

    Research output: Contribution to journalArticlepeer-review

  72. E-pub ahead of print

    Safety and probiotic evaluation of two Bacillus strains producing antioxidant compounds

    Kotowicz, N., Bhardwaj, R. K., Ferreira, W., Huynh, H., Olender, A., Ramirez, J. & Cutting, S., 16 Sep 2019, (E-pub ahead of print) In: Beneficial microbes. 10, 7, p. 759-771 13 p.

    Research output: Contribution to journalArticlepeer-review

  73. Published

    Prothrombin Complex Concentrates are Superior to Fresh Frozen Plasma for Emergency Reversal of Vitamin K Antagonists: A Meta-Analysis in 2606 Subjects

    Hill, R., Han, T., Lubormirova, I., Math, N., Bentley, P. & Sharma, P., Sep 2019, In: Drugs. 79, 14, p. 1557-1565 9 p.

    Research output: Contribution to journalArticlepeer-review

  74. E-pub ahead of print

    Current status of stroke in Qatar: Including data from the BRAINS study

    Jallow, E., Han, T., Sharma, S. & Sharma, P., 18 Aug 2019, (E-pub ahead of print) In: JRSM cardiovascular disease. 8, p. 1-13 13 p.

    Research output: Contribution to journalArticlepeer-review

  75. E-pub ahead of print

    Vaccination of macaques with DNA followed by adenoviral vectors encoding SIV gag alone delays infection by repeated mucosal challenge with SIV

    Almond, N., Berry, N., Stebbings, R., Preston, M., Ham, C., Page, M., Ferguson, D., Rose, N., Li, B., Mee, E. T., Hassall, M., Stahl-Hennig, C., Athanasopoulos, T., Papagatsias, T., Herath, S., Benlahrech, A., Dickson, G., Meiser, A. & Patterson, S., 14 Aug 2019, (E-pub ahead of print) In: Journal of virology. p. 1-38 38 p.

    Research output: Contribution to journalArticlepeer-review

  76. Published

    Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data

    Sharma, P., 1 Jul 2019, In: Stroke. 50, 7, p. 1734-1741 8 p.

    Research output: Contribution to journalArticlepeer-review

  77. E-pub ahead of print

    Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

    Lu-Nguyen, N., Ferry, A., Schnell, F. J., Hanson, G. J., Popplewell, L., Dickson, G. & Malerba, A., 10 Jun 2019, (E-pub ahead of print) In: Human Molecular Genetics. ddz125.

    Research output: Contribution to journalArticlepeer-review

  78. Published

    Overexpression of the dopamine receptor‐interacting protein Alix/AIP1 modulates NMDA receptor‐triggered cell death

    Syed Salim, S., Nasir, J. & Chen, P., Jun 2019, In: FEBS Letters. 593, 12, p. 1381-1391 11 p.

    Research output: Contribution to journalArticlepeer-review

  79. Published

    Removing epoxy underfill between neighbouring components using acid for component chip-off

    Heckmann, T., McEvoy, J., Markantonakis, K., Akram, R. N. & Naccache, D., Jun 2019, In: digital investigation. 29, p. 198-209 12 p.

    Research output: Contribution to journalArticlepeer-review

  80. Published

    Zebrafish otolith biomineralization requires polyketide synthase

    Thiessen, K. D., Grzegorski, S. J., Chin, Y., Higuchi, L. N., Wilkinson, C. J., Shavit, J. A. & Kramer, K. L., Jun 2019, In: MECHANISMS OF DEVELOPMENT. 157, p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  81. E-pub ahead of print

    White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts – The MRI-GENIE study

    on behalf of the MRI-GENIE Investigators, 29 May 2019, (E-pub ahead of print) In: NeuroImage: Clinical. 23, p. 1-13 13 p., 101884.

    Research output: Contribution to journalArticlepeer-review

  82. Published

    Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy

    Malerba, A., Roth, F., Harish, P., Dhiab, J., Lu-Nguyen, N., Cappellari, O., Jarmin, S., Mahoudeau, A., Ythier, V., Laine, J., Negroni, E., Abgueguen, E., Simonelig, M., Guedat, P., Mouly, V., Butler-Browne, G., Voisset, C., Dickson, G. & Trollet, C., 15 May 2019, In: Human Molecular Genetics. 28, 10, p. 1694-1708 15 p., ddz007.

    Research output: Contribution to journalArticlepeer-review

  83. E-pub ahead of print

    Advice on avoiding the Valley of Death: insights from a 3Rs model of aversive and emetic compound identification

    Williams, R. & Andrews, P., 2 Apr 2019, (E-pub ahead of print) In: ALTEX. p. 1-4 4 p.

    Research output: Contribution to journalLetterpeer-review

  84. E-pub ahead of print

    Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function

    Sharma, D., Otto, G., Warren, E., Beesley, P., King, J. S. & Williams, R., 26 Feb 2019, (E-pub ahead of print) In: Autophagy. 15, 8, p. 1407-1418 12 p.

    Research output: Contribution to journalArticlepeer-review

  85. Published

    Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

    Chauhan, G. & Sharma, P., 29 Jan 2019, In: Neurology. 92, 5, p. 1-19 19 p.

    Research output: Contribution to journalArticlepeer-review

  86. Published

    Dictyostelium discoideum as a pharmacological model system to study the mechanisms of medicinal drugs and natural products

    Schaf, J., Damstra-Oddy, J. & Williams, R. S. B., 2019, In: International Journal of Developmental Biology. 63, p. 541-550 10 p.

    Research output: Contribution to journalArticlepeer-review

  87. Published

    Titanium Kirschner Wires Resist Biofilms Better Than Stainless Steel and Hydroxyapatite-coated Wires: An In Vitro Study

    McEvoy, J., Martin, P., Khaleel, A. & Dissanayeke, S., 2019, In: Strategies in Trauma and Limb Reconstruction. 14, 2, p. 57-64 8 p.

    Research output: Contribution to journalArticlepeer-review

  88. 2018
  89. E-pub ahead of print

    Two-electron redox chemistry of p-nitro- and p-cyanobenzene diazohydroxides

    McEvoy, J., Pham, N., Le, H., Fernandez, M., Farmer, R. & Mahapatro, S., 13 Dec 2018, (E-pub ahead of print) In: Rsc advances. 8, 73, p. 41762-41766 5 p.

    Research output: Contribution to journalArticlepeer-review

  90. Published

    GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    MEGASTROKE Consortium, 3 Dec 2018, In: Nature Communications. 9, p. 1-14 14 p., 5141.

    Research output: Contribution to journalArticlepeer-review

  91. Published

    Ingestion of plastic by fish: A comparison of Thames Estuary and Firth of Clyde populations

    McGoran, A. R., Cowie, P. R., Clark, P. F., McEvoy, J. & Morritt, D., Dec 2018, In: Marine Pollution Bulletin. 137, p. 12-23 12 p.

    Research output: Contribution to journalArticlepeer-review

  92. Published

    A family with PTEN mutations with malignancy and an unusually high number of offspring with autism spectrum disorder: a case report

    Gruhl, S., Sharma, P. & Han, T., 28 Nov 2018, In: Journal of Medical Case Reports. 12, p. 1-6 6 p., 353.

    Research output: Contribution to journalArticlepeer-review

  93. Published

    Impact of Bacillus spp. spores and gentamicin on the gastrointestinal microbiota of suckling and newly weaned piglets

    Cutting, S., 27 Nov 2018, In: PLoS ONE. 13, 11, p. 1-22 22 p., e0207382.

    Research output: Contribution to journalArticlepeer-review

  94. Published

    Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

    Sharma, P., METASTROKE Consortium of the ISGC & WTCCC-2 Consortium , 1 Nov 2018, In: PLoS ONE. 13, 11, p. 1-12 12 p., e0206554.

    Research output: Contribution to journalArticlepeer-review

  95. Published

    Perampanel and decanoic acid show synergistic action against AMPA receptors and seizures

    Augustin, K., Williams, S., Cunningham, M., Anita, D., Friedrich, M., Jayasekera, A., Hussain, M., Holliman, D., Mitchell, P., Jenkins, A., Chen, P., Walker, M. & Williams, R., Nov 2018, In: Epilepsia. 59, 11, p. e172-e178 7 p.

    Research output: Contribution to journalArticlepeer-review

  96. Published

    A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures

    Hiller, M., Falzarano, M. S., Garcia-Jimenez, I., Sardone, V., Verheul, R. C., Popplewell, L., Anthony, K., Ruiz-Del-Yerro, E., Osman, H., Goeman, J. J., Mamchaoui, K., Dickson, G., Ferlini, A., Muntoni, F., Aartsma-Rus, A., Arechavala-Gomeza, V., Datson, N. A. & Spitali, P., 2 Oct 2018, In: PLoS ONE. 13, 10, p. 1-15 15 p., e0204485.

    Research output: Contribution to journalArticlepeer-review

  97. Published
  98. Published

    The localisation of the heparin binding sites of human and murine interleukin-12 within the carboxyterminal domain of the P40 subunit

    Garnier, P., Mummery, R., Forster, M. J., Mulloy, B., Gibbs, R. V. & Rider, C. C., Oct 2018, In: Cytokine. 110, p. 159-168 10 p.

    Research output: Contribution to journalArticlepeer-review

  99. Published

    Editorial of the Special Issue: Antisense Therapies

    Popplewell, L. J., 27 Sep 2018, In: Biomedicines. 6, 4, p. 1-2 2 p., 95.

    Research output: Contribution to journalArticlepeer-review

  100. E-pub ahead of print

    Impact of early-life events on the susceptibility to Clostridium difficile colonisation and infection in the offspring of the pig

    Grześkowiak, Ł., Pieper, R., Huynh, H., Cutting, S., Vahjen, W. & Zentek, J., 25 Sep 2018, (E-pub ahead of print) In: Gut Microbes. 10, 2, p. 251-259 9 p.

    Research output: Contribution to journalArticlepeer-review

  101. Published

    Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria

    Passmore, I., Letertre, M., Preston, M., Bianconi, I., Harrison, M. A., Nasher, F., Kaur, H., Hong, H., Baines, S., Cutting, S., Swann, J., Wren, B. & Dawson, L. F., 12 Sep 2018, In: PLoS Pathogens. 14, 9, p. 1-31 31 p., e1007191.

    Research output: Contribution to journalArticlepeer-review

  102. E-pub ahead of print

    Predictive model of length of stay in hospital among older patients

    Lisk, R., Uddin, M., Parbhoo, A., Yeong, K., Fluck, D., Sharma, P., Lean, M. & Han, T., 6 Sep 2018, (E-pub ahead of print) In: Aging Clinical and Experimental Research . p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

  103. E-pub ahead of print

    Antisense Oligonucleotide Targeting of 3'-UTR of mRNA for Expression Knockdown

    Golshirazi, G., Ciszewski, L., Lu-Nguyen, N. & Popplewell, L., 1 Sep 2018, (E-pub ahead of print) In: Methods in Molecular Biology. 1828, p. 91-124 34 p.

    Research output: Contribution to journalArticlepeer-review

  104. E-pub ahead of print

    Systemic Intravenous Administration of Antisense Therapeutics for Combinatorial Dystrophin and Myostatin Exon Splice Modulation

    Lu-Nguyen, N., Dickson, G. & Malerba, A., 1 Sep 2018, (E-pub ahead of print) In: Methods in Molecular Biology. 1828, p. 343-354 12 p.

    Research output: Contribution to journalArticlepeer-review

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