1. 2014
  2. Published

    Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

    Lu-Nguyen, N., Broadstock, M., Schliesser, M. G., Bartholomae, C., von Kalle, C., Schmidt, M. & Yáñez-Muñoz, R. J. 18 Mar 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  3. Published

    Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors (IDLVs)

    Kymalainen, H., Appelt, J-U., Giordano, F. A., Davies, A. F., Ogilvie, C. M., Ahmed, S. G., Laufs, S., Schmidt, M., Bode, J., Yáñez-Muñoz, R. J. & Dickson, G. 2 Feb 2014 In : Human Gene Therapy.

    Research output: Contribution to journalArticle

  4. Published

    Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

    Sharma, P. & 26 others Malik, R., Bevan, S., Nalls, M. A., Holliday, E. G., Devan, W. J., Cheng, Y-C., Ibrahim-Verbaas, C. A., Verhaaren, B. F. J., Bis, J. C., Joon, A. Y., de Stefano, A. L., Fornage, M., Psaty, B. M., Ikram, M. A., Launer, L. J., van Duijn, C. M., Mitchell, B. D., Rosand, J., Meschia, J. F., Levi, C., Rothwell, P. M., Sudlow, C., Markus, H. S., Seshadri, S., Dichgans, M. & Wellcome Trust Case Control Consortium 2 Feb 2014 In : Stroke; a journal of cerebral circulation. 45, 2, p. 394-402 9 p.

    Research output: Contribution to journalArticle

  5. Published

    New developments in the use of gene therapy to treat Duchenne muscular dystrophy

    Jarmin, S., Kymalainen, H., Popplewell, L. & Dickson, G. Feb 2014 In : Expert Opinion on Biological Therapy. 14, 2, p. 209-30 22 p.

    Research output: Contribution to journalArticle

  6. Published

    Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid

    Chang, P., Walker, M. C. & Williams, R. Feb 2014 In : Neurobiology of Disease. 62, p. 296–306 10 p.

    Research output: Contribution to journalArticle

  7. Published
  8. Published

    Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

    Sharma, P. & 39 others Dichgans, M., Malik, R., König, I. R., Rosand, J., Clarke, R., Gretarsdottir, S., Thorleifsson, G., Mitchell, B. D., Assimes, T. L., Levi, C., O'Donnell, C. J., Fornage, M., Thorsteinsdottir, U., Psaty, B. M., Hengstenberg, C., Seshadri, S., Erdmann, J., Bis, J. C., Peters, A., Boncoraglio, G. B., März, W., Meschia, J. F., Kathiresan, S., Ikram, M. A., McPherson, R., Stefansson, K., Sudlow, C., Reilly, M. P., Thompson, J. R., Hopewell, J. C., Chambers, J. C., Watkins, H., Rothwell, P. M., Roberts, R., Markus, H. S., Samani, N. J., Farrall, M., Schunkert, H. & METASTROKE Consortium Jan 2014 In : Stroke; a journal of cerebral circulation. 45, 1, p. 24-36 13 p.

    Research output: Contribution to journalArticle

  9. Published

    A southern blot protocol to detect chimeric nuclease-mediated gene repair

    Rocca, C. J., Abdul-Razak, H. H., Holmes, M. C., Gregory, P. D. & Yáñez-Muñoz, R. J. 2014 In : Methods in Molecular Biology. 1114, p. 325-38 14 p.

    Research output: Contribution to journalArticle

  10. Published
  11. Published
  12. Published

    Design of Fast Chip Calorimetry Accessory for In-situ X-ray Nanobeam Experiments

    Odarchenko, Y., Rosenthal, M., Doblas, D., Hernandez, J., G, P., Di Cola, E., Burghammer, M., Soloviev, M. & Ivanov, D. A. 2014

    Research output: Contribution to conferenceAbstract

  13. Forthcoming

    Etiologic Ischemic Stroke Phenotypes in the NINDS Stroke Genetics Network

    Sharma, P. & 53 others Ay, H., Arsava, E. M., Andsberg, G., Benner, T., Brown, R., Chapman Smith, S., Cole, J., Delavaran, H., Dichgans, M., Engström, G., Giralt-Steinhauer, E., Grewal, R., Gwinn, K., Jern, C., Jimenez-Conde, J., Jood, K., Katsnelson, M., Kissela, B., Kittner, S., Kleindorfer, D., Labovitz, D., Lanfranconi, S., Lee, J-M., Lehm, M., Lemmens, R., Levi, C., Li, L., Lindgren, A., Markus, H., McArdle, P., Melander, O., Norrving, B., Reddy Peddareddygari, L., Pedersen, A., Pera, J., Rannikmäe, K., Rexrode, K., Rhodes, J., Rich, S., Roquer, J., Rosand, J., Rothwell, P., Rundek, T., Sacco, R., Schmidt, R., Schürks, M., Seiler, S., Slowik, A., Sudlow, C., N Thijs, V., Woodfield, R., Worrall, B. & Meschia, J. 2014 In : Stroke.

    Research output: Contribution to journalArticle

  14. Published

    Fusion of Ubiquitin to HIV Gag Impairs Human Monocyte-Derived Dendritic Cell Maturation and Reduces Ability to Induce Gag T Cell Responses

    Herath, S., Benlahrech, A., Papagatsias, T., Athanasopoulos, T., Bouzeboudjen, Z., Hervouet, C., Klavinskis, L., Meiser, A., Kelleher, P., Dickson, G. & Patterson, S. 2014 In : PLoS One. 9, 2, p. e88327

    Research output: Contribution to journalArticle

  15. Published

    Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

    Bartus, K., James, N. D., Didangelos, A., Bosch, K. D., Verhaagen, J., Yáñez (or Yáñez-Muñoz), R. J., Rogers, J. H., Schneider, B. L., Muir, E. M. & Bradbury, E. J. 2014 In : The Journal of Neuroscience. 34, 14, p. 4822– 4836

    Research output: Contribution to journalArticle

  16. Published

    Prediction of stroke thrombolysis outcome using CT brain machine learning

    Bentley, P., Ganesalingam, J., Carlton Jones, A. L., Mahady, K., Epton, S., Rinne, P., Sharma, P., Halse, O., Mehta, A. & Rueckert, D. 2014 In : NeuroImage. Clinical. 4, p. 635-40 6 p.

    Research output: Contribution to journalArticle

  17. 2013
  18. Published

    Lentiviral Vector-Mediated RNA Silencing in the Central Nervous System

    Hutson, T. H., Foster, E., Moon, L. D. F. & Yáñez-Muñoz, R. J. 1 Nov 2013 In : Human Gene Therapy. Methods.

    Research output: Contribution to journalArticle

  19. Published

    Genome-wide analysis of blood pressure variability and ischemic stroke

    Cotlarciuc, I. , Sharma, P. & 33 others Yadav, S., Munroe, P. B., Khan, M. S., Nalls, M. A., Bevan, S., Cheng, Y-C., Chen, W-M., Malik, R., McCarthy, N. S., Holliday, E. G., Speed, D., Hasan, N., Pucek, M., Rinne, P. E., Sever, P., Stanton, A., Shields, D. C., Maguire, J. M., McEvoy, M., Scott, R. J., Ferrucci, L., Macleod, M. J., Attia, J., Markus, H. S., Sale, M. M., Worrall, B. B., Mitchell, B. D., Dichgans, M., Sudlow, C., Meschia, J. F., Rothwell, P. M., Caulfield, M. & International Stroke Genetics Consortium Oct 2013 In : Stroke; a journal of cerebral circulation. 44, 10, p. 2703-9 7 p.

    Research output: Contribution to journalArticle

  20. Published

    Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes

    Sharma, P. & 40 others Meschia, J. F., Arnett, D. K., Ay, H., Brown, R. D., Benavente, O. R., Cole, J. W., de Bakker, P. I. W., Dichgans, M., Doheny, K. F., Fornage, M., Grewal, R. P., Gwinn, K., Jern, C., Conde, J. J., Johnson, J. A., Jood, K., Laurie, C. C., Lee, J-M., Lindgren, A., Markus, H. S., McArdle, P. F., McClure, L. A., Mitchell, B. D., Schmidt, R., Rexrode, K. M., Rich, S. S., Rosand, J., Rothwell, P. M., Rundek, T., Sacco, R. L., Shuldiner, A. R., Slowik, A., Wassertheil-Smoller, S., Sudlow, C., Thijs, V. N. S., Woo, D., Worrall, B. B., Wu, O., Kittner, S. J. & NINDS SiGN Study Oct 2013 In : Stroke; a journal of cerebral circulation. 44, 10, p. 2694-702 9 p.

    Research output: Contribution to journalArticle

  21. Published

    Transgene delivery to endothelial cultures derived from porcine carotid artery ex vivo

    Andoh, J., Sawyer, B., Szewczyk, K., Nortley, M., Rossetti, T., Loftus, I. M., Yáñez-Muñoz, R. J. & Hainsworth, A. H. Oct 2013 In : Translational Stroke Research. 4, 5, p. 507-14 8 p.

    Research output: Contribution to journalArticle

  22. Published

    Triple dissociation of attention networks in stroke according to lesion location

    Rinne, P., Hassan, M., Goniotakis, D., Chohan, K., Sharma, P., Langdon, D., Soto, D. & Bentley, P. 27 Aug 2013 In : Neurology. 81, 9, p. 812-20 9 p.

    Research output: Contribution to journalArticle

  23. Published

    Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in

    Popplewell, L., Koo, T., Leclerc, X., Duclert, A., Mamchaoui, K., Gouble, A., Mouly, V., Voit, T., Pâques, F., Cédrone, F., Isman, O., Yáñez (or Yáñez-Muñoz), R. J. & Dickson, G. Jul 2013 In : Human Gene Therapy. 24, 7, p. 692-701 10 p.

    Research output: Contribution to journalArticle

  24. Published

    Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

    Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., Yip, P., Wanisch, K., Caraballo-Miralles, V., Olmos, G., Lladó, J., McMahon, S. B. & Yáñez-Muñoz, R. J. Jun 2013 In : Gene Therapy. 20, p. 645-657

    Research output: Contribution to journalArticle

  25. Published

    Functional characterization of Clostridium difficile spore coat proteins

    Permpoonpattana, P., Phetcharaburanin, J., Mikelsone, A., Dembek, M., Tan, S., Brisson, M-C., La Ragione, R., Brisson, A. R., Fairweather, N., Hong, H. A. & Cutting, S. M. 1 Apr 2013 In : Journal of Bacteriology. 195, 7, p. 1492-1503 12 p.

    Research output: Contribution to journalArticle

  26. Published
  27. Published

    Elevated Transcription of the Gene QSOX1 Encoding Quiescin Q6 Sulfhydryl Oxidase 1 in Breast Cancer

    Soloviev, M., Esteves, M. P., Amiri, F., Crompton, M. R. & Rider, C. 27 Feb 2013 In : PLoS One. 8, 2, e57327

    Research output: Contribution to journalArticle

  28. Published
  29. Published

    Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases

    Dickson, J. G. & 50 others Tremblay, J. P., Xiao, X., Aartsma-Rus, A., Barbas, C., Blau, H. M., Bogdanove, A. J., Boycott, K., Braun, S., Breakefield, X. O., Bueren, J. A., Buschmann, M., Byrne, B. J., Calos, M., Cathomen, T., Chamberlain, J., Chuah, M., Cornetta, K., Davies, K. E., Duchateau, P., Flotte, T. R., Gaudet, D., Gersbach, C. A., Gilbert, R., Glorioso, J., Herzog, R. W., High, K. A., Huang, W., Huard, J., Joung, J. K., Liu, D., Liu, D., Lochmüller, H., Lustig, L., Martens, J., Massie, B., Mavilio, F., Mendell, J. R., Nathwani, A., Ponder, K., Porteus, M., Puymirat, J., Samulski, J., Takeda, S., Thrasher, A., VandenDriessche, T., Wei, Y., Wilson, J. M., Wilton, S. D., Wolfe, J. H. & Gao, G. Feb 2013 In : Molecular Therapy. 21, 2, p. 266-8 3 p.

    Research output: Contribution to journalArticle

  30. Published

    Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung

    Yates, L. L., Schnatwinkel, C., Hazelwood, L., Chessum, L., Paudyal, A., Hilton, H., Romero, M. R., Wilde, J., Bogani, D., Sanderson, J., Formstone, C., Murdoch, J. N., Niswander, L. A., Greenfield, A. & Dean, C. H. 15 Jan 2013 In : Developmental Biology. 373, 2, p. 267-280 14 p.

    Research output: Contribution to journalArticle

  31. Published

    A novel human receptor involved in bitter tastant detection identified using the model organism Dictyostelium discoideum

    Robery, S., Tyson, R., Dinh, C., Kuspa, A., Noegel, A., Bretschneider, T., Andrews, P. L. R. & Williams, R. S. B. 2013 In : Journal of Cell Science.

    Research output: Contribution to journalArticle

  32. Published

    Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

    Bachy, V., Hervouet, C., Becker, P. D., Chorro, L., Carlin, L. M., Herath, S., Papagatsias, T., Barbaroux, J-B., Oh, S-J., Benlahrech, A., Athanasopoulos, T., Dickson, G., Patterson, S., Kwon, S-Y., Geissmann, F. & Klavinskis, L. S. 2013 In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

  33. Published

    Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

    Novorol, C., Burkhardt, J., Wood, K. J., Iqbal, A., Roque, C., Coutts, N., Almeida, A. D., He, J., Wilkinson, C. J. & Harris, W. A. 2013 In : Open biology. 3, 10, p. 130065

    Research output: Contribution to journalArticle

  34. Published

    Mucosal Vaccination against Tuberculosis Using Inert Bioparticles

    Reljic, R., Sibley, L., Huang, J-M., Pepponi, I., Hoppe, A., Huynh, H. & Cutting, S. M. 2013 In : Infection and Immunity. 81, 11, p. 4071-4080

    Research output: Contribution to journalArticle

  35. Forthcoming

    Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner

    Waheed, A., Ludtmann, M., Pakes, N., Robery, S., Kuspa, A., Dinh, C., Baines, D. L., Williams, R. & Carew, M. 2013 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  36. Published

    Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy

    Raz, V., Sterrenburg, E., Routledge, S., Venema, A., van der Sluijs, B. M., Trollet, C., Dickson, G., van Engelen, B. G. M., van der Maarel, S. M. & Antoniou, M. N. 2013 In : BMC Neurology. 13, p. 70

    Research output: Contribution to journalArticle

  37. Forthcoming

    The search for better epilepsy treatments: from slime mould to coconuts

    Williams, R. & Walker, M. C. 2013 In : Biochemical Society Transactions. 41

    Research output: Contribution to journalLiterature review

  38. Published

    Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

    Pakes, N., Veltman, D. M. & Williams, R. 2013 In : Small GTPases. 4, 1, p. 1-6 6 p.

    Research output: Contribution to journalLiterature review

  39. 2012
  40. Published

    Fragmentation of SIV-gag Vaccine Induces Broader T Cell Responses

    Benlahrech, A., Meiser, A., Herath, S., Papagatsias, T., Athanasopoulos, T., Li, F., Self, S., Bachy, V., Hervouet, C., Logan, K., Klavinskis, L., Dickson, G. & Patterson, S. 31 Oct 2012 In : PLoS One. 7, 10, 13 p., ARTN e48038

    Research output: Contribution to journalArticle

  41. Published

    Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

    Cotlarciuc, I. , Sharma, P. & 58 others Holliday, E. G., Maguire, J. M., Evans, T-J., Koblar, S. A., Jannes, J., Sturm, J. W., Hankey, G. J., Baker, R., Golledge, J., Parsons, M. W., Malik, R., McEvoy, M., Biros, E., Lewis, M. D., Lincz, L. F., Peel, R., Oldmeadow, C., Smith, W., Moscato, P., Barlera, S., Bevan, S., Bis, J. C., Boerwinkle, E., Boncoraglio, G. B., Brott, T. G., Brown, R. D., Cheng, Y-C., Cole, J. W., Devan, W. J., Fornage, M., Furie, K. L., Grétarsdóttir, S., Gschwendtner, A., Ikram, M. A., Longstreth, W. T., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Parati, E. A., Psaty, B. M., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Traylor, M., Verhaaren, B. F. J., Wiggins, K. L., Worrall, B. B., Sudlow, C., Rothwell, P. M., Farrall, M., Dichgans, M., Rosand, J., Markus, H. S., Scott, R. J., Levi, C., Attia, J. & Australian Stroke Genetics Collaborative Oct 2012 In : Nature Genetics. 44, 10, p. 1147-51 5 p.

    Research output: Contribution to journalArticle

  42. Published

    Seizure control by ketogenic diet-associated medium chain fatty acids

    Chang, P., Terbach, N., Plant, N., Chen, P. E., Walker, M. C. & Williams, R. S. B. Jun 2012 In : Neuropharmacology. 69, p. 105-114

    Research output: Contribution to journalArticle

  43. Published

    The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium

    Pakes, N. K., Veltman, D. M., Rivero, F., Nasir, J., Insall, R. & Williams, R. S. B. 15 May 2012 In : Journal of Cell Science. 125, Pt 10, p. 2457-65 9 p.

    Research output: Contribution to journalArticle

  44. Published

    Highly potent delivery method of gp160 envelope vaccine combining lentivirus-like particles and DNA electrotransfer

    Vandermeulen, G., Athanasopoulos, T., Trundley, A., Foster, K., Préat, V., Yáñez-Muñoz, R. J. & Dickson, G. 10 May 2012 In : Journal of Controlled Release. 159, 3, p. 376–383

    Research output: Contribution to journalArticle

  45. Published

    Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds

    Elphick, L. M., Pawolleck, N., Guschina, I. A., Chaieb, L., Eikel, D., Nau, H., Harwood, J. L., Plant, N. J. & Williams, R. S. B. Mar 2012 In : Disease Models and Mechanisms. 5, 2, p. 231-240 10 p.

    Research output: Contribution to journalArticle

  46. Published

    Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

    Hutson, T. H., Verhaagen, J., Yáñez-Muñoz, R. J. & Moon, L. D. F. Jan 2012 In : Gene Therapy. 19, 1, p. 49-60 12 p.

    Research output: Contribution to journalArticle

  47. Published

    AMP-Activated Protein Kinase (AMPK) - Dependent and -Independent Pathways Regulate Hypoxic Inhibition of Transepithelial Na(+) Transport Across Human Airway Epithelial Cells

    Tan, C. D., Smolenski, R. T., Harhun, M. I., Patel, H. K., Ahmed, S. G., Wanisch, K., Yáñez (or Yáñez-Muñoz) , R. J. & Baines, D. L. 2012 In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  48. Published

    Amyloid-β Acts as a Regulator of Neurotransmitter Release Disrupting the Interaction between Synaptophysin and VAMP2

    Russell, C. L., Semerdjieva, S., Empson, R. M., Austen, B. M., Beesley, P. W. & Alifragis, P. 2012 In : PLoS One. 7, 8, p. e43201

    Research output: Contribution to journalArticle

  49. Published

    Assembly of protein building blocks using a short synthetic peptide

    Ferrari, E., Soloviev, M., Niranjan, D., Arsenault, J., Gu, C., Vallis, Y., O'Brien, J. & Davletov, B. 2012 In : Bioconjugate Chemistry. 23, 3, p. 479-84 6 p.

    Research output: Contribution to journalArticle

  50. Published

    Bio-repository of DNA in stroke: a study protocol of three ancestral populations

    Cotlarciuc, I., Khan, M. S., Maheshwari, A., Yadav, S., Khan, F. Y., Al-Hail, H., de Silva, R., Gorthi, S. P., Gupta, S., Sharma, S. R., Sylaja, P. N., Prasad, K. & Sharma, P. 2012 In : JRSM cardiovascular disease. 1, 4

    Research output: Contribution to journalArticle

  51. Published

    Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail

    Thoby-Brisson, M., Bouvier, J., Glasco, D. M., Stewart, M. E., Dean, C., Murdoch, J. N., Champagnat, J., Fortin, G. & Chandrasekhar, A. 2012 In : PLoS One. 7, 2, p. e31140

    Research output: Contribution to journalArticle

  52. Published

    Challenges for gene therapy of CNS disorders and implications for Parkinson's disease therapies

    Broadstock, M. & Yáñez (or Yáñez-Muñoz) , R. J. 2012 In : Human Gene Therapy. 23, 4, p. 340-3 4 p.

    Research output: Contribution to journalComment/debate

  53. Published

    Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

    Yáñez (or Yáñez-Muñoz) , R. J. , Dickson, G. , Popplewell, L. & 28 others Daboussi, F., Zaslavskiy, M., Poirot, L., Loperfido, M., Gouble, A., Guyot, V., Leduc, S., Galetto, R., Grizot, S., Oficjalska, D., Perez, C., Delacôte, F., Dupuy, A., Chion-Sotinel, I., Le Clerre, D., Lebuhotel, C., Danos, O., Lemaire, F., Oussedik, K., Cédrone, F., Epinat, J-C., Smith, J., Koo, T., Vandendriessche, T., Chuah, M. K., Duclert, A., Duchateau, P. & Pâques, F. 2012 In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  54. Published
  55. Published

    Effect of gold nanoparticle conjugation on the activity and stability of functional proteins

    Bailes, J., Gazi, S., Ivanova, R. & Soloviev, M. 2012 In : Methods in Molecular Biology. 906, p. 89-99 11 p.

    Research output: Contribution to journalArticle

  56. Published

    Evaluation of Bacillus subtilis strains as probiotics and their potential as a food ingredient

    Permpoonpattana, P., Hong, H. A., Khaneja, R. & Cutting, S. M. 2012 In : Beneficial microbes. 3, 2, p. 127-35 9 p.

    Research output: Contribution to journalArticle

  57. Published

    Genetic Therapeutic Approaches for Duchenne Muscular Dystrophy

    Foster, H., Popplewell, L. J. & Dickson, G. 2012 In : Human Gene Therapy.

    Research output: Contribution to journalLiterature review

  58. Published

    Gold nanoparticle antibody conjugates for use in competitive lateral flow assays

    Bailes, J., Mayoss, S., Teale, P. & Soloviev, M. 2012 In : Methods in Molecular Biology. 906, p. 45-55 11 p.

    Research output: Contribution to journalArticle

  59. Published

    Killed Bacillus subtilis spores as a mucosal adjuvant for an H5N1 vaccine

    Song, M., Hong, H. A., Huang, J-M., Colenutt, C., Khang, D. D., Nguyen, T. V. A., Park, S-M., Shim, B-S., Song, H. H., Cheon, I. S., Jang, J. E., Choi, J., Choi, Y. K., Stadler, K. & Cutting, S. M. 2012 In : Vaccine. 30, 22, p. 3266-77 12 p.

    Research output: Contribution to journalArticle

  60. Published

    Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones

    Hutson, T. H., Foster, E., Dawes, J. M., Hindges, R., Yáñez (or Yáñez-Muñoz) , R. J. & Moon, L. D. F. 2012 In : Journal of Gene Medicine. 14, 5, p. 299-315 17 p.

    Research output: Contribution to journalArticle

  61. Published

    Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in duchenne muscular dystrophy

    Popplewell, L. J., Abu-Dayya, A., Khana, T., Flinterman, M., Khalique, N. A., Raju, L., Opstad, C. L., Sliwka, H-R., Partali, V., Dickson, G. & Pungente, M. D. 2012 In : Molecules. 17, 2, p. 1138-48 11 p.

    Research output: Contribution to journalArticle

  62. Published

    Optimizing antisense oligonucleotides using phosphorodiamidate morpholino oligomers

    Popplewell, L. J., Malerba, A. & Dickson, G. 2012 In : Methods in Molecular Biology. 867, p. 143-67 25 p.

    Research output: Contribution to journalArticle

  63. Published

    Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

    de Klerk, E., Venema, A., Anvar, S. Y., Goeman, J. J., Hu, O., Trollet, C., Dickson, G., den Dunnen, J. T., van der Maarel, S. M., Raz, V. & 't Hoen, P. A. C. 2012 In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  64. Published

    Spores, sporulation and germination

    Prajapati, R. S. & Cutting, S. 2012 Molecular Medical Microbiology. Academic Press, p. 199 208 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  65. Published

    The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

    Chang, P., Orabi, B., Deranieh, R. M., Dham, M., Hoeller, O., Shimshoni, J. A., Yagen, B., Bialer, M., Greenberg, M. L., Walker, M. C. & Williams, R. S. B. 2012 In : Disease Models and Mechanisms. 5, p. 115-124

    Research output: Contribution to journalArticle

  66. Published
  67. Published

    The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium

    Stowe, T. R., Wilkinson, C. J., Iqbal, A. & Stearns, T. 2012 In : Molecular biology of the cell. 23, 17, p. 3322-35 14 p.

    Research output: Contribution to journalArticle

  68. Published

    The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled

    Glasco, D. M., Sittaramane, V., Bryant, W., Fritzsch, B., Sawant, A., Paudyal, A., Stewart, M., Andre, P., Cadete Vilhais-Neto, G., Yang, Y., Song, M-R., Murdoch, J. N. & Chandrasekhar, A. 2012 In : Developmental Biology. 369, 2, p. 211-22 12 p.

    Research output: Contribution to journalArticle

  69. Published

    The Use of EST Expression Matrixes for the Quality Control of Gene Expression Data

    Milnthorpe, A. T. & Soloviev, M. 2012 In : PLoS One. 7, 3, p. e32966

    Research output: Contribution to journalArticle

  70. Published

    Zizimin and Dock guanine nucleotide exchange factors in cell function and disease

    Pakes, N. K., Veltman, D. M. & Williams, R. 2012 In : Small GTPases. 4, 1

    Research output: Contribution to journalArticle

  71. 2011
  72. Published

    Surface layers of Clostridium difficile endospores

    Permpoonpattana, P., Tolls, E. H., Nadem, R., Tan, S., Brisson, A. & Cutting, S. M. Dec 2011 In : Journal of Bacteriology. 193, 23, p. 6461-6470 10 p.

    Research output: Contribution to journalArticle

  73. Published

    Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research

    Robery, S., Mukanowa, J., Percie du Sert, N., Andrews, P. L. R. & Williams, R. S. B. 8 Sep 2011 In : PLoS One. 6, 9, p. e24439

    Research output: Contribution to journalArticle

  74. Published

    Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog

    Koo, T., Okada, T., Athanasopoulos, T., Foster, H., Takeda, S. & Dickson, G. Sep 2011 In : Journal of Gene Medicine. 13, 9, p. 497-506 10 p.

    Research output: Contribution to journalArticle

  75. Published

    Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

    Cirak, S., Arechavala-Gomeza, V., Guglieri, M., Feng, L., Torelli, S., Anthony, K., Abbs, S., Garralda, M. E., Bourke, J., Wells, D. J., Dickson, G., Wood, M. J. A., Wilton, S. D., Straub, V., Kole, R., Shrewsbury, S. B., Sewry, C., Morgan, J. E., Bushby, K. & Muntoni, F. 13 Aug 2011 In : The Lancet. 378, 9791, p. 595-605 11 p.

    Research output: Contribution to journalArticle

  76. Published

    Bio-electrospraying and aerodynamically assisted bio-jetting the model eukaryotic Dictyostelium discoideum: assessing stress and developmental competency post treatment

    Pakes, N. K., Jayasinghe, S. N. & Williams, R. S. B. 7 Aug 2011 In : Journal of the Royal Society. Interface. 8, 61, p. 1185-1191 7 p.

    Research output: Contribution to journalArticle

  77. Published

    Getting to the Heart of Things in the Field of Cardiovascular Gene Therapy

    Dickson, G. Aug 2011 In : Human Gene Therapy. 22, 8, p. 911-912 2 p.

    Research output: Contribution to journalEditorial

  78. Published
  79. Published

    Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium

    Terbach, N., Shah, R., Kelemen, R., Klein, P. S., Gordienko, D., Brown, N. A., Wilkinson, C. J. & Williams, R. S. B. 1 Jul 2011 In : Journal of Cell Science. 124, Pt 13, p. 2267-2276 10 p.

    Research output: Contribution to journalArticle

  80. Published

    Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B

    Permpoonpattana, P., Hong, H. A., Phetcharaburanin, J., Huang, J-M., Cook, J., Fairweather, N. F. & Cutting, S. M. Jun 2011 In : Infection and Immunity. 79, 6, p. 2295-2302 8 p.

    Research output: Contribution to journalArticle

  81. Published

    Identification and the developmental formation of carotenoid pigments in the yellow/orange Bacillus spore-formers

    Perez-Fons, L., Steiger, S., Khaneja, R., Bramley, P. M., Cutting, S. M., Sandmann, G. & Fraser, P. D. Mar 2011 In : Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids . 1811, 3, p. 177-185 9 p.

    Research output: Contribution to journalArticle

  82. Published

    Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

    Malerba, A., Sharp, P. S., Graham, I. R., Arechavala-Gomeza, V., Foster, K., Muntoni, F., Wells, D. J. & Dickson, G. Feb 2011 In : Molecular Therapy. 19, 2, p. 345-354

    Research output: Contribution to journalArticle

  83. Published

    Molecular pharmacology in a simple model system: Implicating MAP kinase and phosphoinositide signalling in bipolar disorder

    Ludtmann, M. H. R., Boeckeler, K. & Williams, R. S. B. Feb 2011 In : Seminars in Cell and Developmental Biology. 22, 1, p. 105-113 9 p.

    Research output: Contribution to journalLiterature review

  84. Published
  85. Published

    Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle

    Evans, V. C., Graham, I. R., Athanasopoulos, T., Galley, D. J., Jackson, C. L., Simons, J. P., Dickson, G. & Owen, J. S. 2011 In : Metabolism: clinical and experimental. 60, 4, p. 491-8

    Research output: Contribution to journalArticle

  86. Published
  87. Published

    Bacillus probiotics

    Cutting, S. M. 2011 In : Food Microbiology. 28, 2, p. 214-20 7 p.

    Research output: Contribution to journalArticle

  88. Published

    Bioinformatic and Functional Optimization of Antisense Phosphorodiamidate Morpholino Oligomers (PMOs) for Therapeutic Modulation of RNA Splicing in Muscle

    Popplewell, L. J., Graham, I. R., Malerba, A. & Dickson, G. 2011 In : Methods in Molecular Biology. 709, p. 153-78 26 p.

    Research output: Contribution to journalArticle

  89. Published

    Carbohydrate-active enzymes from pigmented Bacilli: a genomic approach to assess carbohydrate utilization and degradation

    Manzo, N., D'Apuzzo, E., Coutinho, P. M., Cutting, S. M., Henrissat, B. & Ricca, E. 2011 In : BMC Microbiology. 11, p. 198

    Research output: Contribution to journalArticle

  90. Published

    Chip-Based Proteomics

    Bailes, J., Milnthorpe, A., Smieszek, S. & Soloviev, M. 2011 Molecular Analysis and Genome Discovery. Rapley, R. & Harbron, S. (eds.). 2nd ed. p. 193-218 Ch.9

    Research output: Chapter in Book/Report/Conference proceedingChapter

  91. Published

    Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer

    Mao, X., Boyd, L. K., Yáñez-Muñoz, R. J., Chaplin, T., Xue, L., Lin, D., Shan, L., Berney, D. M., Young, B. D. & Lu, Y. J. 2011 In : American Journal of Cancer Research. 1, p. 604-617

    Research output: Contribution to journalArticle

  92. Published

    Codon optimization of the microdystrophin gene for duchene muscular dystrophy gene therapy

    Athanasopoulos, T., Foster, H., Foster, K. & Dickson, G. 2011 In : Methods in Molecular Biology. 709, p. 21-37 17 p.

    Research output: Contribution to journalArticle

  93. Published

    Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

    Pichavant, C., Aartsma-Rus, A., Clemens, P. R., Davies, K. E., Dickson, G., Takeda, S., Wilton, S. D., Wolff, J. A., Wooddell, C. I., Xiao, X. & Tremblay, J. P. 2011 In : Molecular Therapy. 19, 5, p. 830-40 11 p.

    Research output: Contribution to journalLiterature review

  94. Published
  95. Published

    Deregulation of the ubiquitin-proteasome system is the predominant molecular pathology in OPMD animal models and patients

    Anvar, S. Y., 't Hoen, P. A., Venema, A., van der Sluijs, B., van Engelen, B., Snoeck, M., Vissing, J., Trollet, C., Dickson, G., Chartier, A., Simonelig, M., van Ommen, G-J. B., van der Maarel, S. M. & Raz, V. 2011 In : Skeletal Muscle. 1, 1, p. 15

    Research output: Contribution to journalArticle

  96. Published

    Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms

    Milnthorpe, A. T. & Soloviev, M. 2011 In : BMC Bioinformatics. 12, p. 97

    Research output: Contribution to journalArticle

  97. Published

    Lentiviral vector integration profiles differ in rodent postmitotic tissues

    Bartholomae, C. C., Arens, A., Balaggan, K. S., Yáñez-Muñoz, R. J., Montini, E., Howe, S. J., Paruzynski, A., Korn, B., Appelt, U., MacNeil, A., Cesana, D., Abel, U., Glimm, H., Naldini, L., Ali, R. R., Thrasher, A. J., von Kalle, C. & Schmidt, M. 2011 In : Molecular Therapy. 19, 4, p. 703-710

    Research output: Contribution to journalArticle

  98. Published

    Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

    Zhao, R-R., Muir, E. M., Alves, J. N., Rickman, H., Allan, A. Y., Kwok, J. C., Roet, K. C. D., Verhaagen, J., Schneider, B. L., Bensadoun, J-C., Ahmed, S. G., Yáñez (or Yáñez-Muñoz) , R. J., Keynes, R. J., Fawcett, J. W. & Rogers, J. H. 2011 In : Journal of Neuroscience Methods. 201, 1, p. 228-38 11 p.

    Research output: Contribution to journalArticle

  99. Published

    Lobe-specific functions of Ca2+·calmodulin in alphaCa2+·calmodulin-dependent protein kinase II activation

    Jama, A. M., Gabriel, J., Al-Nagar, A. J., Martin, S., Baig, S. Z., Soleymani, H., Chowdhury, Z., Beesley, P. & Török, K. 2011 In : Journal of Biological Chemistry. 286, 14, p. 12308-16 9 p.

    Research output: Contribution to journalArticle

  100. Published

    RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense

    Riyahi, T. Y., Frese, F., Steinert, M., Omosigho, N. N., Glöckner, G., Eichinger, L., Orabi, B., Williams, R. S. B. & Noegel, A. A. 2011 In : PLoS One. 6, 11, p. e27311

    Research output: Contribution to journalArticle

  101. Published

    Transcription Factor Rational Design Improves Directed Differentiation of Human Mesenchymal Stem Cells Into Skeletal Myocytes

    Gonçalves, M. A., Janssen, J. M., Nguyen, Q. G., Athanasopoulos, T., Hauschka, S. D., Dickson, G. & de Vries, A. A. 2011 In : Molecular Therapy. 19, 7, p. 1331-41

    Research output: Contribution to journalArticle

  102. 2010
  103. Published

    NanoLock polypeptide for the permanent immobilization of recombinant proteins on SNAP25 functionalized supports

    Ferrari, E., Darios, F., Soloviev, M. & Davletov, B. 1 Nov 2010 In : European Cells and Materials. 20, SUPPL.3, p. 80 1 p.

    Research output: Contribution to journalArticle

  104. Published

    Canine microdystrophin results in remarkable expression and improvement in muscle pathology in a canine model of Duchenne Muscular Dystrophy following AAV gene transfer

    Koo, T., Shin, J. H., Athanasopoulos, T., Takashi, O., Foster, H., Shin'ichi, T. & Dickson, G. Oct 2010 In : Human Gene Therapy. 21, 10, p. 1469-1470 2 p.

    Research output: Contribution to journalArticle

  105. Published

    Evaluation of the truncated products of exon and multiple exon skipping in DMD therapy

    Foster, K., Jarmin, S., Beley, C., Foster, H., Garcia, L. & Dickson, G. Oct 2010 In : Neuromuscular Disorders. 20, 9-10, p. 642 1 p.

    Research output: Contribution to journalArticle