Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

Ngoc Lu-Nguyen; Martin Broadstock; Maximilian G Schliesser; Cynthia Bartholomae; Christof von Kalle; Manfred Schmidt; Rafael J Yáñez-Muñoz

doi:10.1089/hum.2014.003

Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

Ngoc Lu-Nguyen
, Martin Broadstock
, Maximilian G Schliesser
, Cynthia Bartholomae
, Christof von Kalle
, Manfred Schmidt
, Rafael J Yáñez-Muñoz

Research output: Contribution to journal › Article › peer-review

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Original language	English
Journal	Human Gene Therapy
DOIs	https://doi.org/10.1089/hum.2014.003
Publication status	Published - 18 Mar 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1089/hum.2014.003

LuNguyenHGT_GDNF_Complete_PureUploadAccepted author manuscript, 1.2 MB

Integration-deficient lentiviral vectors delivering neurotrophic factors for gene therapy of Parkinson’s disease
Lu-Nguyen, N. (Student), Broadstock, M. (Fellow) & Yáñez-Muñoz, R. J. (PI)
1/10/09 → 1/07/13
Project: Research

10th Annual Conference of The BSGCT (UK)
Lu-Nguyen, N. (Speaker)
2013
Activity: Talk, presentation or media contribution › Oral presentation
Parkinson’s UK Research Conference (UK)
Lu-Nguyen, N. (Speaker)
2012
Activity: Talk, presentation or media contribution › Oral presentation

College overseas research scholarship - RHUL
Lu-Nguyen, N. (Recipient), 2009
Prize: Prize (including medals and awards)
Poster prize and Fairbairn Award nomination - British Society for Gene and Cell Therapy
Lu-Nguyen, N. (Recipient), 2013
Prize: Prize (including medals and awards)
Travel Grant - Parkinson's UK
Lu-Nguyen, N. (Recipient), 2012
Prize: Prize (including medals and awards)

Cite this

Lu-Nguyen, N., Broadstock, M., Schliesser, M. G., Bartholomae, C., von Kalle, C., Schmidt, M., & Yáñez-Muñoz, R. J. (2014). Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease. Human Gene Therapy. https://doi.org/10.1089/hum.2014.003

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title = "Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease",

author = "Ngoc Lu-Nguyen and Martin Broadstock and Schliesser, \{Maximilian G\} and Cynthia Bartholomae and \{von Kalle\}, Christof and Manfred Schmidt and Y{\'a}{\~n}ez-Mu{\~n}oz, \{Rafael J\}",

year = "2014",

month = mar,

day = "18",

doi = "10.1089/hum.2014.003",

language = "English",

journal = "Human Gene Therapy",

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publisher = "SAGE Publications Ltd",

}

TY - JOUR

T1 - Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

AU - Lu-Nguyen, Ngoc

AU - Broadstock, Martin

AU - Schliesser, Maximilian G

AU - Bartholomae, Cynthia

AU - von Kalle, Christof

AU - Schmidt, Manfred

AU - Yáñez-Muñoz, Rafael J

PY - 2014/3/18

Y1 - 2014/3/18

U2 - 10.1089/hum.2014.003

DO - 10.1089/hum.2014.003

M3 - Article

C2 - 24635742

SN - 1043-0342

JO - Human Gene Therapy

JF - Human Gene Therapy

ER -

Transgenic expression of human glial cell line-derived neurotrophic factor (hGDNF) from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease

UN SDGs

Access to Document

Projects

Integration-deficient lentiviral vectors delivering neurotrophic factors for gene therapy of Parkinson’s disease

Activities

10th Annual Conference of The BSGCT (UK)

Parkinson’s UK Research Conference (UK)

Prizes

College overseas research scholarship - RHUL

Poster prize and Fairbairn Award nomination - British Society for Gene and Cell Therapy

Travel Grant - Parkinson's UK

Cite this