The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

Anju Paudyal, Christine Damrau, Victoria L Patterson, Alexander Ermakov, Caroline Formstone, Zuzanna Lalanne, Sara Wells, Xiaowei Lu, Dominic P Norris, Charlotte H Dean, Deborah J Henderson, Jennifer N Murdoch

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)87
JournalBMC Developmental Biology
Publication statusPublished - 2010


  • Animals
  • Cell Polarity
  • Disease Models, Animal
  • Ear, Inner
  • Ethylnitrosourea
  • Heart Defects, Congenital
  • Humans
  • Lung
  • Mice
  • Mutagenesis, Insertional
  • Nerve Tissue Proteins
  • Neural Crest
  • Neural Tube Defects
  • Receptor Protein-Tyrosine Kinases
  • Receptors, G-Protein-Coupled
  • Signal Transduction

Cite this