The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

M. B. Goncalves, E. J. Williams, P. Yip, R. J. Yáñez-Muñoz, G. Williams, P. Doherty

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1118-25
Number of pages8
JournalBritish Journal of Pharmacology
Issue number5
Early online date5 Feb 2010
Publication statusPublished - 2010


  • Animals Brain/drug effects/metabolism Cell Proliferation/drug effects Cyclooxygenase 2/genetics Cyclooxygenase 2 Inhibitors/*pharmacology Female Gene Expression Regulation, Enzymologic Mice Mice, Inbred C57BL Neurogenesis/*drug effects Neurons/drug effects/metabolism Stem Cells/metabolism Sulfonamides/*pharmacology Thiazines/*pharmacology Thiazoles/*pharmacology

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