Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

Andrew D White; Andy C. Tran; Laura Sibley; Charlotte Sarfas; Alexandra L Morrison; Steve Lawrence; Mike Dennis; Simon Clark; Sirine Zadi; Faye Lanni; Emma Rayner; Alastair Copland; Peter  Hart; Gil R Diogo; Mathew Paul; Miyoung Kim; Fergus Gleeson; Francisco Javier Salguero; Mahavir Singh; Matthias Stehr; Simon Cutting; Juan I Basile; Martin Rottenberg; Ann Williams; Sally A Sharpe; Rajko Reljic

doi:10.3389/fimmu.2023.1246826

Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

Andrew D White
, Andy C. Tran
, Laura Sibley
, Charlotte Sarfas
, Alexandra L Morrison
, Steve Lawrence
, Mike Dennis
, Simon Clark
, Sirine Zadi
, Faye Lanni
, Emma Rayner
, Alastair Copland
, Peter Hart
, Gil R Diogo
, Mathew Paul
, Miyoung Kim
, Fergus Gleeson
, Francisco Javier Salguero
, Mahavir Singh
, Matthias Stehr

Simon Cutting, Juan I Basile, Martin Rottenberg, Ann Williams, Sally A Sharpe, Rajko Reljic

Research output: Contribution to journal › Article › peer-review

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Original language	English
Journal	Frontiers in Immunology
Volume	14
DOIs	https://doi.org/10.3389/fimmu.2023.1246826
Publication status	Published - 10 Oct 2023

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SDG 3 Good Health and Well-being

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10.3389/fimmu.2023.1246826Licence: CC BY

Final ManuscriptFinal published version, 7.79 MBLicence: CC BY

Cite this

White, A. D., Tran, A. C., Sibley, L., Sarfas, C., Morrison, A. L., Lawrence, S., Dennis, M., Clark, S., Zadi, S., Lanni, F., Rayner, E., Copland, A., Hart, P., Diogo, G. R., Paul, M., Kim, M., Gleeson, F., Salguero, F. J., Singh, M., ... Reljic, R. (2023). Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1246826

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year = "2023",

month = oct,

day = "10",

doi = "10.3389/fimmu.2023.1246826",

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White, AD, Tran, AC, Sibley, L, Sarfas, C, Morrison, AL, Lawrence, S, Dennis, M, Clark, S, Zadi, S, Lanni, F, Rayner, E, Copland, A, Hart, P, Diogo, GR, Paul, M, Kim, M, Gleeson, F, Salguero, FJ, Singh, M, Stehr, M, Cutting, S, Basile, JI, Rottenberg, M, Williams, A, Sharpe, SA & Reljic, R 2023, 'Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates', Frontiers in Immunology, vol. 14. https://doi.org/10.3389/fimmu.2023.1246826

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T1 - Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

AU - White, Andrew D

AU - Tran, Andy C.

AU - Sibley, Laura

AU - Sarfas, Charlotte

AU - Morrison, Alexandra L

AU - Lawrence, Steve

AU - Dennis, Mike

AU - Clark, Simon

AU - Zadi, Sirine

AU - Lanni, Faye

AU - Rayner, Emma

AU - Copland, Alastair

AU - Hart, Peter

AU - Diogo, Gil R

AU - Paul, Mathew

AU - Kim, Miyoung

AU - Gleeson, Fergus

AU - Salguero, Francisco Javier

AU - Singh, Mahavir

AU - Stehr, Matthias

AU - Cutting, Simon

AU - Basile, Juan I

AU - Rottenberg, Martin

AU - Williams, Ann

AU - Sharpe, Sally A

AU - Reljic, Rajko

PY - 2023/10/10

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U2 - 10.3389/fimmu.2023.1246826

DO - 10.3389/fimmu.2023.1246826

M3 - Article

SN - 1664-3224

VL - 14

JO - Frontiers in Immunology

JF - Frontiers in Immunology

ER -