Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

Katalin Bartus; Nicholas D James; Athanasios Didangelos; Karen D Bosch; Joost Verhaagen; Rafael J. Yáñez (or Yáñez-Muñoz); John H Rogers; Bernard L Schneider; Elizabeth M Muir; Elizabeth J. Bradbury

doi:10.1523/JNEUROSCI.4369-13.2014

Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

Katalin Bartus
, Nicholas D James
, Athanasios Didangelos
, Karen D Bosch
, Joost Verhaagen
, Rafael J. Yáñez (or Yáñez-Muñoz)
, John H Rogers
, Bernard L Schneider
, Elizabeth M Muir
, Elizabeth J. Bradbury

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	4822– 4836
Journal	The Journal of Neuroscience
Volume	34
Issue number	14
Early online date	2 Apr 2014
DOIs	https://doi.org/10.1523/JNEUROSCI.4369-13.2014
Publication status	Published - 2014

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10.1523/JNEUROSCI.4369-13.2014

Cite this

Bartus, K., James, N. D., Didangelos, A., Bosch, K. D., Verhaagen, J., Yáñez (or Yáñez-Muñoz), R. J., Rogers, J. H., Schneider, B. L., Muir, E. M., & Bradbury, E. J. (2014). Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury. The Journal of Neuroscience, 34(14), 4822– 4836. https://doi.org/10.1523/JNEUROSCI.4369-13.2014

@article{2fecaedc550b4c40af3657a4150e0582,

title = "Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury",

author = "Katalin Bartus and James, \{Nicholas D\} and Athanasios Didangelos and Bosch, \{Karen D\} and Joost Verhaagen and \{Y{\'a}{\~n}ez (or Y{\'a}{\~n}ez-Mu{\~n}oz)\}, \{Rafael J.\} and Rogers, \{John H\} and Schneider, \{Bernard L\} and Muir, \{Elizabeth M\} and Bradbury, \{Elizabeth J.\}",

year = "2014",

doi = "10.1523/JNEUROSCI.4369-13.2014",

language = "English",

volume = "34",

pages = "4822– 4836",

journal = "The Journal of Neuroscience",

issn = "0270-6474",

publisher = "Society for Neuroscience",

number = "14",

}

Bartus, K, James, ND, Didangelos, A, Bosch, KD, Verhaagen, J, Yáñez (or Yáñez-Muñoz), RJ, Rogers, JH, Schneider, BL, Muir, EM & Bradbury, EJ 2014, 'Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury', The Journal of Neuroscience, vol. 34, no. 14, pp. 4822– 4836. https://doi.org/10.1523/JNEUROSCI.4369-13.2014

Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury. / Bartus, Katalin; James, Nicholas D; Didangelos, Athanasios et al.
In: The Journal of Neuroscience, Vol. 34, No. 14, 2014, p. 4822– 4836.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

AU - Bartus, Katalin

AU - James, Nicholas D

AU - Didangelos, Athanasios

AU - Bosch, Karen D

AU - Verhaagen, Joost

AU - Yáñez (or Yáñez-Muñoz), Rafael J.

AU - Rogers, John H

AU - Schneider, Bernard L

AU - Muir, Elizabeth M

AU - Bradbury, Elizabeth J.

PY - 2014

Y1 - 2014

U2 - 10.1523/JNEUROSCI.4369-13.2014

DO - 10.1523/JNEUROSCI.4369-13.2014

M3 - Article

SN - 0270-6474

VL - 34

SP - 4822

EP - 4836

JO - The Journal of Neuroscience

JF - The Journal of Neuroscience

IS - 14

ER -

Bartus K, James ND, Didangelos A, Bosch KD, Verhaagen J, Yáñez (or Yáñez-Muñoz) RJ et al. Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury. The Journal of Neuroscience. 2014;34(14):4822– 4836. Epub 2014 Apr 2. doi: 10.1523/JNEUROSCI.4369-13.2014