Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E

J D  Harris; S  Schepelmann; T  Athanasopoulos; I R  Graham; A K  Stannard; Z  Mohri; V  Hill; D G  Hassall; J S  Owen; G  Dickson

doi:10.1038/sj.gt.3301615

Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E

J D Harris
, S Schepelmann
, T Athanasopoulos
, I R Graham
, A K Stannard
, Z Mohri
, V Hill
, D G Hassall
, J S Owen
, G Dickson

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	21-29
Number of pages	9
Journal	Human Gene Therapy
Volume	9
Issue number	1
DOIs	https://doi.org/10.1038/sj.gt.3301615
Publication status	Published - 31 Jan 2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

gene therapy
apolipoprotein E
atherosclerosis
AAV
BONE-MARROW-TRANSPLANTATION
DIRECTED GENE-TRANSFER
COAGULATION FACTOR-IX
SEVERE HYPERCHOLESTEROLEMIA
INTRAMUSCULAR INJECTION
VIRAL VECTORS
CHOLESTEROL ACYLTRANSFERASE
CARDIOVASCULAR-DISEASE
TRANSGENE EXPRESSION
PLATELET-AGGREGATION

Access to Document

10.1038/sj.gt.3301615

Cite this

Harris, J. D., Schepelmann, S., Athanasopoulos, T., Graham, I. R., Stannard, A. K., Mohri, Z., Hill, V., Hassall, D. G., Owen, J. S., & Dickson, G. (2002). Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E. Human Gene Therapy, 9(1), 21-29. https://doi.org/10.1038/sj.gt.3301615

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keywords = "gene therapy, apolipoprotein E, atherosclerosis, AAV, BONE-MARROW-TRANSPLANTATION, DIRECTED GENE-TRANSFER, COAGULATION FACTOR-IX, SEVERE HYPERCHOLESTEROLEMIA, INTRAMUSCULAR INJECTION, VIRAL VECTORS, CHOLESTEROL ACYLTRANSFERASE, CARDIOVASCULAR-DISEASE, TRANSGENE EXPRESSION, PLATELET-AGGREGATION",

author = "Harris, \{J D\} and S Schepelmann and T Athanasopoulos and Graham, \{I R\} and Stannard, \{A K\} and Z Mohri and V Hill and Hassall, \{D G\} and Owen, \{J S\} and G Dickson",

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Harris, JD, Schepelmann, S, Athanasopoulos, T, Graham, IR, Stannard, AK, Mohri, Z, Hill, V, Hassall, DG, Owen, JS & Dickson, G 2002, 'Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E', Human Gene Therapy, vol. 9, no. 1, pp. 21-29. https://doi.org/10.1038/sj.gt.3301615

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AU - Harris, J D

AU - Schepelmann, S

AU - Athanasopoulos, T

AU - Graham, I R

AU - Stannard, A K

AU - Mohri, Z

AU - Hill, V

AU - Hassall, D G

AU - Owen, J S

AU - Dickson, G

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KW - DIRECTED GENE-TRANSFER

KW - COAGULATION FACTOR-IX

KW - SEVERE HYPERCHOLESTEROLEMIA

KW - INTRAMUSCULAR INJECTION

KW - VIRAL VECTORS

KW - CHOLESTEROL ACYLTRANSFERASE

KW - CARDIOVASCULAR-DISEASE

KW - TRANSGENE EXPRESSION

KW - PLATELET-AGGREGATION

U2 - 10.1038/sj.gt.3301615

DO - 10.1038/sj.gt.3301615

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