Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Virginie J M Verhoeven; Pirro G Hysi; Robert Wojciechowski; Qiao Fan; Jeremy A Guggenheim; René Höhn; Stuart MacGregor; Alex W Hewitt; Abhishek Nag; Ching-Yu Cheng; Ekaterina Yonova-Doing; Xin Zhou; M Kamran Ikram; Gabriëlle H S Buitendijk; George McMahon; John P Kemp; Beate St Pourcain; Claire L Simpson; Kari-Matti Mäkelä; Terho Lehtimäki; Mika Kähönen; Andrew D Paterson; S Mohsen Hosseini; Hoi Suen Wong; Liang Xu; Jost B Jonas; Olavi Pärssinen; Juho Wedenoja; Shea Ping Yip; Daniel W H Ho; Chi Pui Pang; Li Jia Chen; Kathryn P Burdon; Jamie E Craig; Barbara E K Klein; Ronald Klein; Toomas Haller; Andres Metspalu; Chiea-Chuen Khor; E-Shyong Tai; Tin Aung; Eranga Vithana; Wan-Ting Tay; Veluchamy A Barathi; Peng Chen; Ruoying Li; Jiemin Liao; Yingfeng Zheng; Rick T Ong; Ioana Cotlarciuc; Consortium for Refractive Error and Myopia (CREAM)

doi:10.1038/ng.2554

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Virginie J M Verhoeven
, Pirro G Hysi
, Robert Wojciechowski
, Qiao Fan
, Jeremy A Guggenheim
, René Höhn
, Stuart MacGregor
, Alex W Hewitt
, Abhishek Nag
, Ching-Yu Cheng
, Ekaterina Yonova-Doing
, Xin Zhou
, M Kamran Ikram
, Gabriëlle H S Buitendijk
, George McMahon
, John P Kemp
, Beate St Pourcain
, Claire L Simpson
, Kari-Matti Mäkelä
, Terho Lehtimäki

Mika Kähönen, Andrew D Paterson, S Mohsen Hosseini, Hoi Suen Wong, Liang Xu, Jost B Jonas, Olavi Pärssinen, Juho Wedenoja, Shea Ping Yip, Daniel W H Ho, Chi Pui Pang, Li Jia Chen, Kathryn P Burdon, Jamie E Craig, Barbara E K Klein, Ronald Klein, Toomas Haller, Andres Metspalu, Chiea-Chuen Khor, E-Shyong Tai, Tin Aung, Eranga Vithana, Wan-Ting Tay, Veluchamy A Barathi, Peng Chen, Ruoying Li, Jiemin Liao, Yingfeng Zheng, Rick T Ong, Ioana Cotlarciuc, Consortium for Refractive Error and Myopia (CREAM)

Biological Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	314-8
Number of pages	5
Journal	Nature Genetics
Volume	45
Issue number	3
DOIs	https://doi.org/10.1038/ng.2554
Publication status	Published - Mar 2013

Keywords

Alcohol Oxidoreductases
Asian Continental Ancestry Group
Bone Morphogenetic Protein 2
European Continental Ancestry Group
Genetic Predisposition to Disease
Genome-Wide Association Study
Homeodomain Proteins
Humans
KCNQ Potassium Channels
Laminin
Myopia
Receptors, AMPA
Refractive Errors
Risk Factors
Serine Proteases
Trans-Activators

Access to Document

10.1038/ng.2554

Cite this

Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Höhn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P., Pourcain, B. S., Simpson, C. L., Mäkelä, K.-M., ... Consortium for Refractive Error and Myopia (CREAM) (2013). Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nature Genetics, 45(3), 314-8. https://doi.org/10.1038/ng.2554

@article{cfd336dd8b14420ea4ac2bb773c71a03,

title = "Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia",

keywords = "Alcohol Oxidoreductases, Asian Continental Ancestry Group, Bone Morphogenetic Protein 2, European Continental Ancestry Group, Genetic Predisposition to Disease, Genome-Wide Association Study, Homeodomain Proteins, Humans, KCNQ Potassium Channels, Laminin, Myopia, Receptors, AMPA, Refractive Errors, Risk Factors, Serine Proteases, Trans-Activators",

author = "Verhoeven, \{Virginie J M\} and Hysi, \{Pirro G\} and Robert Wojciechowski and Qiao Fan and Guggenheim, \{Jeremy A\} and Ren{\'e} H{\"o}hn and Stuart MacGregor and Hewitt, \{Alex W\} and Abhishek Nag and Ching-Yu Cheng and Ekaterina Yonova-Doing and Xin Zhou and Ikram, \{M Kamran\} and Buitendijk, \{Gabri{\"e}lle H S\} and George McMahon and Kemp, \{John P\} and Pourcain, \{Beate St\} and Simpson, \{Claire L\} and Kari-Matti M{\"a}kel{\"a} and Terho Lehtim{\"a}ki and Mika K{\"a}h{\"o}nen and Paterson, \{Andrew D\} and Hosseini, \{S Mohsen\} and Wong, \{Hoi Suen\} and Liang Xu and Jonas, \{Jost B\} and Olavi P{\"a}rssinen and Juho Wedenoja and Yip, \{Shea Ping\} and Ho, \{Daniel W H\} and Pang, \{Chi Pui\} and Chen, \{Li Jia\} and Burdon, \{Kathryn P\} and Craig, \{Jamie E\} and Klein, \{Barbara E K\} and Ronald Klein and Toomas Haller and Andres Metspalu and Chiea-Chuen Khor and E-Shyong Tai and Tin Aung and Eranga Vithana and Wan-Ting Tay and Barathi, \{Veluchamy A\} and Peng Chen and Ruoying Li and Jiemin Liao and Yingfeng Zheng and Ong, \{Rick T\} and Ioana Cotlarciuc and \{Consortium for Refractive Error and Myopia (CREAM)\}",

year = "2013",

month = mar,

doi = "10.1038/ng.2554",

language = "English",

volume = "45",

pages = "314--8",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Research",

number = "3",

}

Verhoeven, VJM, Hysi, PG, Wojciechowski, R, Fan, Q, Guggenheim, JA, Höhn, R, MacGregor, S, Hewitt, AW, Nag, A, Cheng, C-Y, Yonova-Doing, E, Zhou, X, Ikram, MK, Buitendijk, GHS, McMahon, G, Kemp, JP, Pourcain, BS, Simpson, CL, Mäkelä, K-M, Lehtimäki, T, Kähönen, M, Paterson, AD, Hosseini, SM, Wong, HS, Xu, L, Jonas, JB, Pärssinen, O, Wedenoja, J, Yip, SP, Ho, DWH, Pang, CP, Chen, LJ, Burdon, KP, Craig, JE, Klein, BEK, Klein, R, Haller, T, Metspalu, A, Khor, C-C, Tai, E-S, Aung, T, Vithana, E, Tay, W-T, Barathi, VA, Chen, P, Li, R, Liao, J, Zheng, Y, Ong, RT, Cotlarciuc, I & Consortium for Refractive Error and Myopia (CREAM) 2013, 'Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia', Nature Genetics, vol. 45, no. 3, pp. 314-8. https://doi.org/10.1038/ng.2554

TY - JOUR

T1 - Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

AU - Verhoeven, Virginie J M

AU - Hysi, Pirro G

AU - Wojciechowski, Robert

AU - Fan, Qiao

AU - Guggenheim, Jeremy A

AU - Höhn, René

AU - MacGregor, Stuart

AU - Hewitt, Alex W

AU - Nag, Abhishek

AU - Cheng, Ching-Yu

AU - Yonova-Doing, Ekaterina

AU - Zhou, Xin

AU - Ikram, M Kamran

AU - Buitendijk, Gabriëlle H S

AU - McMahon, George

AU - Kemp, John P

AU - Pourcain, Beate St

AU - Simpson, Claire L

AU - Mäkelä, Kari-Matti

AU - Lehtimäki, Terho

AU - Kähönen, Mika

AU - Paterson, Andrew D

AU - Hosseini, S Mohsen

AU - Wong, Hoi Suen

AU - Xu, Liang

AU - Jonas, Jost B

AU - Pärssinen, Olavi

AU - Wedenoja, Juho

AU - Yip, Shea Ping

AU - Ho, Daniel W H

AU - Pang, Chi Pui

AU - Chen, Li Jia

AU - Burdon, Kathryn P

AU - Craig, Jamie E

AU - Klein, Barbara E K

AU - Klein, Ronald

AU - Haller, Toomas

AU - Metspalu, Andres

AU - Khor, Chiea-Chuen

AU - Tai, E-Shyong

AU - Aung, Tin

AU - Vithana, Eranga

AU - Tay, Wan-Ting

AU - Barathi, Veluchamy A

AU - Chen, Peng

AU - Li, Ruoying

AU - Liao, Jiemin

AU - Zheng, Yingfeng

AU - Ong, Rick T

AU - Cotlarciuc, Ioana

AU - Consortium for Refractive Error and Myopia (CREAM)

PY - 2013/3

Y1 - 2013/3

KW - Alcohol Oxidoreductases

KW - Asian Continental Ancestry Group

KW - Bone Morphogenetic Protein 2

KW - European Continental Ancestry Group

KW - Genetic Predisposition to Disease

KW - Genome-Wide Association Study

KW - Homeodomain Proteins

KW - Humans

KW - KCNQ Potassium Channels

KW - Laminin

KW - Myopia

KW - Receptors, AMPA

KW - Refractive Errors

KW - Risk Factors

KW - Serine Proteases

KW - Trans-Activators

U2 - 10.1038/ng.2554

DO - 10.1038/ng.2554

M3 - Article

C2 - 23396134

SN - 1061-4036

VL - 45

SP - 314

EP - 318

JO - Nature Genetics

JF - Nature Genetics

IS - 3

ER -