Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty

A D Tagalakis, I R Graham, D R Riddell, J G Dickson, J S Owen

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)13226-30
Number of pages5
JournalJournal of Biological Chemistry
Volume276
Issue number16
DOIs
Publication statusPublished - 2001

Keywords

  • Amino Acid Substitution
  • Animals
  • Apolipoprotein E2
  • Apolipoprotein E3
  • Apolipoproteins E
  • Base Sequence
  • CHO Cells
  • Cricetinae
  • Crosses, Genetic
  • Female
  • Gene Therapy
  • Genomic Library
  • Genotype
  • Humans
  • Lymphocytes
  • Male
  • Mice
  • Mice, Transgenic
  • Oligodeoxyribonucleotides
  • Oligoribonucleotides
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • RNA, Messenger
  • Recombinant Fusion Proteins
  • Transfection

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