Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants

Magdalena Dory; Elizabeth  Hatzimasoura; Brigitta M.  Kállai; Szilvia K.  Nagy; Katalin  Jäger; Zsuzsanna  Darula; Tímea V.  Nádai; Tamás  Mészáros; Enrique Lopez Juez; Beáta  Barnabás; Klaus  Palme; Laszlo Bogre; Franck A.  Ditengou; Róbert  Dóczi

doi:10.1002/1873-3468.12929

Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants

Magdalena Dory, Elizabeth Hatzimasoura, Brigitta M. Kállai, Szilvia K. Nagy, Katalin Jäger, Zsuzsanna Darula, Tímea V. Nádai, Tamás Mészáros, Enrique Lopez Juez, Beáta Barnabás, Klaus Palme, Laszlo Bogre, Franck A. Ditengou, Róbert Dóczi

Research output: Contribution to journal › Letter › peer-review

Abstract

Plant growth flexibly adapts to environmental conditions, implying cross-talk between environmental signalling and developmental regulation. Here we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen-activated protein kinase (MAPK) sites, adjacent to the phosphorylation sites of the well-characterised AGC kinase, PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally-activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK-mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma-membrane localisation of PIN1. MAPK-mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth.

Original language	English
Pages (from-to)	89-102
Number of pages	14
Journal	FEBS Letters
Volume	592
Issue number	1
Early online date	2 Dec 2017
DOIs	https://doi.org/10.1002/1873-3468.12929
Publication status	Published - Jan 2018

Keywords

Arabidopsis, MAP kinase, PIN, protein phosphorylation, signalling

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10.1002/1873-3468.12929Licence: CC BY

Bilateral NSF/BIO-BBSRC - Translational landscape to link cell growth with proliferation in the root meristem
Bogre, L. (PI) & Paccanaro, A. (PI)
Biotechnology&BioSci Research BBSRC
1/07/15 → 30/06/18
Project: Research
MAP kinase signalling to the plant cell cycle: an integrated functional genomic approach
Bogre, L. (PI)
Biotechnology&BioSci Research BBSRC
7/06/04 → 6/12/07
Project: Research

Cite this

Dory, M., Hatzimasoura, E., Kállai, B. M., Nagy, S. K., Jäger, K., Darula, Z., Nádai, T. V., Mészáros, T., Lopez Juez, E., Barnabás, B., Palme, K., Bogre, L., Ditengou, F. A., & Dóczi, R. (2018). Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants. FEBS Letters, 592(1), 89-102. https://doi.org/10.1002/1873-3468.12929

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title = "Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants",

abstract = "Plant growth flexibly adapts to environmental conditions, implying cross-talk between environmental signalling and developmental regulation. Here we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen-activated protein kinase (MAPK) sites, adjacent to the phosphorylation sites of the well-characterised AGC kinase, PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally-activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK-mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma-membrane localisation of PIN1. MAPK-mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth.",

keywords = "Arabidopsis, MAP kinase, PIN, protein phosphorylation, signalling",

author = "Magdalena Dory and Elizabeth Hatzimasoura and K{\'a}llai, {Brigitta M.} and Nagy, {Szilvia K.} and Katalin J{\"a}ger and Zsuzsanna Darula and N{\'a}dai, {T{\'i}mea V.} and Tam{\'a}s M{\'e}sz{\'a}ros and {Lopez Juez}, Enrique and Be{\'a}ta Barnab{\'a}s and Klaus Palme and Laszlo Bogre and Ditengou, {Franck A.} and R{\'o}bert D{\'o}czi",

year = "2018",

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doi = "10.1002/1873-3468.12929",

language = "English",

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Dory, M, Hatzimasoura, E, Kállai, BM, Nagy, SK, Jäger, K, Darula, Z, Nádai, TV, Mészáros, T, Lopez Juez, E, Barnabás, B, Palme, K, Bogre, L, Ditengou, FA & Dóczi, R 2018, 'Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants', FEBS Letters, vol. 592, no. 1, pp. 89-102. https://doi.org/10.1002/1873-3468.12929

TY - JOUR

T1 - Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants

AU - Dory, Magdalena

AU - Hatzimasoura, Elizabeth

AU - Kállai, Brigitta M.

AU - Nagy, Szilvia K.

AU - Jäger, Katalin

AU - Darula, Zsuzsanna

AU - Nádai, Tímea V.

AU - Mészáros, Tamás

AU - Lopez Juez, Enrique

AU - Barnabás, Beáta

AU - Palme, Klaus

AU - Bogre, Laszlo

AU - Ditengou, Franck A.

AU - Dóczi, Róbert

PY - 2018/1

Y1 - 2018/1

N2 - Plant growth flexibly adapts to environmental conditions, implying cross-talk between environmental signalling and developmental regulation. Here we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen-activated protein kinase (MAPK) sites, adjacent to the phosphorylation sites of the well-characterised AGC kinase, PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally-activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK-mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma-membrane localisation of PIN1. MAPK-mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth.

AB - Plant growth flexibly adapts to environmental conditions, implying cross-talk between environmental signalling and developmental regulation. Here we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen-activated protein kinase (MAPK) sites, adjacent to the phosphorylation sites of the well-characterised AGC kinase, PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally-activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK-mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma-membrane localisation of PIN1. MAPK-mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth.

KW - Arabidopsis, MAP kinase, PIN, protein phosphorylation, signalling

U2 - 10.1002/1873-3468.12929

DO - 10.1002/1873-3468.12929

M3 - Letter

SN - 0014-5793

VL - 592

SP - 89

EP - 102

JO - FEBS Letters

JF - FEBS Letters

IS - 1

ER -

Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants

Abstract

Keywords

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Projects

Bilateral NSF/BIO-BBSRC - Translational landscape to link cell growth with proliferation in the root meristem

MAP kinase signalling to the plant cell cycle: an integrated functional genomic approach

Cite this