A Family of Cyclic Lipopeptides Found in Human Isolates of Bacillus Ameliorates Acute Colitis via Direct Agonism of Toll-Like Receptor 2 in a Murine Model of Inflammatory Bowel Disease

Edward Horwell; Maria Vittoria; Huynh A. Hong; Philip Bearn; Simon M. Cutting

doi:10.1007/s10620-024-08534-2

A Family of Cyclic Lipopeptides Found in Human Isolates of Bacillus Ameliorates Acute Colitis via Direct Agonism of Toll-Like Receptor 2 in a Murine Model of Inflammatory Bowel Disease

Edward Horwell
, Maria Vittoria
, Huynh A. Hong
, Philip Bearn
, Simon M. Cutting

Department of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3729-3741
Number of pages	13
Journal	Digestive Diseases and Sciences
Volume	69
Early online date	7 Aug 2024
DOIs	https://doi.org/10.1007/s10620-024-08534-2
Publication status	Published - Oct 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Animal models
Bacillus
Drug discovery
Inflammation
Inflammatory bowel disease
Lipopeptide
Toll-like receptors
Ulcerative colitis

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10.1007/s10620-024-08534-2Licence: CC BY-NC

Cite this

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title = "A Family of Cyclic Lipopeptides Found in Human Isolates of Bacillus Ameliorates Acute Colitis via Direct Agonism of Toll-Like Receptor 2 in a Murine Model of Inflammatory Bowel Disease",

keywords = "Animal models, Bacillus, Drug discovery, Inflammation, Inflammatory bowel disease, Lipopeptide, Toll-like receptors, Ulcerative colitis",

author = "Edward Horwell and Maria Vittoria and Hong, \{Huynh A.\} and Philip Bearn and Cutting, \{Simon M.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = oct,

doi = "10.1007/s10620-024-08534-2",

language = "English",

volume = "69",

pages = "3729--3741",

journal = "Digestive Diseases and Sciences",

issn = "0163-2116",

publisher = "Springer",

}

A Family of Cyclic Lipopeptides Found in Human Isolates of Bacillus Ameliorates Acute Colitis via Direct Agonism of Toll-Like Receptor 2 in a Murine Model of Inflammatory Bowel Disease. / Horwell, Edward; Vittoria, Maria; Hong, Huynh A. et al.
In: Digestive Diseases and Sciences, Vol. 69, 10.2024, p. 3729-3741.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A Family of Cyclic Lipopeptides Found in Human Isolates of Bacillus Ameliorates Acute Colitis via Direct Agonism of Toll-Like Receptor 2 in a Murine Model of Inflammatory Bowel Disease

AU - Horwell, Edward

AU - Vittoria, Maria

AU - Hong, Huynh A.

AU - Bearn, Philip

AU - Cutting, Simon M.

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/10

Y1 - 2024/10

KW - Animal models

KW - Bacillus

KW - Drug discovery

KW - Inflammation

KW - Inflammatory bowel disease

KW - Lipopeptide

KW - Toll-like receptors

KW - Ulcerative colitis

UR - https://www.scopus.com/pages/publications/85200605484

U2 - 10.1007/s10620-024-08534-2

DO - 10.1007/s10620-024-08534-2

M3 - Article

AN - SCOPUS:85200605484

SN - 0163-2116

VL - 69

SP - 3729

EP - 3741

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

ER -

A Family of Cyclic Lipopeptides Found in Human Isolates of Bacillus Ameliorates Acute Colitis via Direct Agonism of Toll-Like Receptor 2 in a Murine Model of Inflammatory Bowel Disease

UN SDGs

Keywords

Access to Document

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