Personal profile
Research interests
The Director of the Institute is Professor Pankaj Sharma. In addition to being its director he is also a consultant neurologist at Imperial College Healthcare NHS Trust.
Professor Sharma holds a University of London Chair of Neurology at Royal Holloway. He is a former British Heart Foundation Clinician Scientist at Cambridge and a Fulbright Scholar at Harvard Medical School. He holds double doctorates from both the University of Cambridge and University of London. Most recently he led the internationally renowned Imperial College Cerebrovascular Research Unit at Imperial College London.
Professor Sharma’s research seeks to use genetics, genomics and proteomics to advance human understanding of cerebrovascular disease in three key areas: prediction, diagnosis and treatment of stroke at the molecular level. He has a particular interest in the genetics of stroke in ethnic minorities, particularly South Asians and Middle Eastern populations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Research output
- 123 Article
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Selective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor
Zhao, X., Yu, C., Adamson, A., Zhao, A., Zhou, H., Sharma, P. & Wang, T., 3 Apr 2026, In: Science Advances. 12, 14Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of mediators of seasonal variation in fatal strokes: a multicentre registry‐based cohort study
Fluck, A., Fry, C., Affley, B., Kakar, P., Sharma, P., Jones, G., Rees, J., Tudose, J., Jones, Y., Finch, J., Davison, J., Bull, E., Robin, J., Fluck, D. & Han, T., Aug 2025, In: Journal of Stroke & Cerebrovascular Diseases. 34, 8, 108360.Research output: Contribution to journal › Article › peer-review
Open Access -
Format of emergency department electronic health records in Europe. The 1 European initiative and the eCREAM proposal
Bertolini, G., Ghilardi, G., Pandolfini, C., Bacchiega, A., Catania, F., Magnini, B., Mitro, P., Notas, G., Prosen, G., Sharma, P., Górka, J. & Nattino, G., 14 Apr 2025, In: Frontiers in Disaster and Emergency Medicine . 3, 1558208.Research output: Contribution to journal › Article › peer-review
Open Access -
Ischemic heart disease among South Asians with ischaemic stroke in three countries across two continents: the BRAINS study
Ken-Dror, G., Sureshkumar, P., Han, T. S., Sharma, S. D., Sylaja , P. N., Khan, F. Y., Prasad, K., Sharma, P. & BRAINS collaborators, Mar 2025, In: Annals of Epidemiology. 103, p. 48-54 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mendelian randomization assessing causal relationship between fibrinogen levels and ischemic stroke
Ken-Dror, G., Khanna, T., Hills, E., Lepert, L., Mughal, S., Han, T. S. & Sharma, P., Feb 2025, In: Journal of Stroke & Cerebrovascular Diseases. 34, 2, 7 p., 108199.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 11 Finished
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BRAINS: Stroke in British Asians
Sharma, P. (PI)
Ashford and St Peter’s Hospitals NHS Foundation Trust
1/01/24 → 31/03/25
Project: Research
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BRAINS AF ANALYSIS ASPH SURREY
Sharma, P. (PI) & Sharma, S. (PI)
Ashford and St Peter’s Hospitals NHS Foundation Trust
1/08/18 → 31/07/21
Project: Research
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An investigation on the genetics of stroke
Sharma, P. (PI)
Ashford and St Peter’s Hospitals NHS Foundation Trust
3/01/17 → 2/01/20
Project: Research
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Understanding stroke caused by cerebral venous thrombosis
Sharma, P. (PI)
1/10/16 → 31/03/18
Project: Research
Activities
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Stroke
Sharma, P. (Participant)
5 Oct 2016Activity: Other › Public engagement, outreach and knowledge exchange - Participation in radio programme
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Educating the South Asian community on stroke and cardiovascular risk reduction
Sharma, P. (Interviewee)
9 May 2015Activity: Other › Public engagement, outreach and knowledge exchange - Participation in TV programme
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Life After Stroke
Sharma, P. (Participant)
11 Mar 2015Activity: Other › Public engagement, outreach and knowledge exchange - Participation in TV programme
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Life After Stroke
Sharma, P. (Participant)
10 Mar 2015Activity: Other › Public engagement, outreach and knowledge exchange - Participation in radio programme
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Life After Stroke
Sharma, P. (Interviewee)
5 Mar 2015Activity: Other › Public engagement, outreach and knowledge exchange - Participation in radio programme