Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeted exon skipping of NF1 exon 17 as a Therapeutic for Neurofibromatosis Type I
Leier, A., Moore, M., Liu, H., Daniel, M., Hyde, A. M., Messiaen, L., Korf, B. R., Selvakumaran, J., Ciszewski, L., Lambert, L., Foote, J., Wallace, M. R., Kesterson, R. A., Dickson, G., Popplewell, L. & Wallis, D., 15 Mar 2022, In: Molecular therapy. Nucleic acids.Research output: Contribution to journal › Article › peer-review
Open Access -
Restoration of Normal NF1 Function with Antisense Morpholino Treatment of Recurrent Pathogenic Patient-Specific Variant c.1466A>G; p.Y489C
Awad, E., Moore, M., Liu, H., Ciszewski, L., Lambert, L., Korf, B. R., Popplewell, L., Kesterson, R. & Wallis, D., 7 Dec 2021, In: Journal of Personalized Medicine. 11, 12, 1320.Research output: Contribution to journal › Article › peer-review
Open Access -
G-quadruplex ligands mediate downregulation of DUX4 expression
Ciszewski, L., Lu-Nguyen, N., Slater, A., Brennan, A., Williams, H. E. L., Dickson, G., Searle, M. S. & Popplewell, L., 17 Mar 2020, In: Nucleic Acids Research. 48, 8, p. 4179-4194 16 p., gkaa146.Research output: Contribution to journal › Article › peer-review
Open Access -
Antisense Oligonucleotide Targeting of 3'-UTR of mRNA for Expression Knockdown
Golshirazi, G., Ciszewski, L., Lu-Nguyen, N. & Popplewell, L., 1 Sept 2018, (E-pub ahead of print) In: Methods in Molecular Biology. 1828, p. 91-124 34 p.Research output: Contribution to journal › Article › peer-review
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G-Quadruplex Nucleic Acid Structures Influence DUX4 Expression in Facioscapulohumeral Muscular Dystrophy
Ciszewski, L., 28 Oct 2018, (Unpublished) 259 p.Research output: Thesis › Doctoral Thesis
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Projects
- 1 Finished
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Development of antisense oligonucleotide drugs to supress expression of the DUX4 protein as a therapy for Fascioscapulohumeral Muscular Dystrophy
Lu-Nguyen, N. (Researcher), Ciszewski, L. (Student), Popplewell, L. (CoPI) & Dickson, G. (PI)
1/08/14 → 31/07/18
Project: Research